Protein Alignment mthl7 and adgrl2b.1

DIOPT Version :10

• Sequence 1: NP_648181.2
• Gene: mthl7 / 38910
• FlyBaseID: FBgn0035847
• Length: 491
• Species: Drosophila melanogaster
• Sequence 2: XP_073767727.1
• Gene: adgrl2b.1 / 110437953
• ZFINID: ZDB-GENE-130116-4
• Length: 1467
• Species: Danio rerio
• Alignment Length: 406
• Identity: 85/406 - (20%)
• Similarity: 155/406 - (38%)
• Gaps: 94/406 - (23%)

  Fly   104 DDGLKEELARFKPYIYFTYMDLQ-ARVPLTDMAIIRDEFFDCDEMIYISDFNYFLEEVSIQIFNK 167
            |.||:........:|....::.: :||.:::..|...|..|.:        |||....|...:::
Zfish   738 DGGLRNHTLTVNSHILSASINKESSRVFVSEPVIFTLEHLDTE--------NYFNPNCSFWNYSE 794

  Fly   168 CGLIVWFQDGKFWVT--VDLFMEKQDY----CLYRHNFDSDFPKSMWIIRHRCTSHISPGSLEIL 226
            ..:      ..:|.|  ..|....:.:    |.:..||       ..::.|| .||...||:..|
Zfish   795 RSM------SGYWSTQGCKLLSTNKTHTTCSCSHLTNF-------AILMVHR-DSHAGEGSVHEL 845

  Fly   227 IIT----------MICFVLTIAVYLYIKKL---RNVTGKCIVCCIVSRFIQCLIMILDHLNLLNG 278
            ::|          ::|..::|..:.:.:.|   ||...|.:  || :.||..|:.::. :|:...
Zfish   846 LLTVITRLGIAVSLVCLAISIFTFCFFRGLQSDRNTIHKNL--CI-NLFIAELLFLVG-INMTEP 906

  Fly   279 --ICSPAGYSSHFFRMASNLWLSVISYHTWKVLTSLNRVDPNYRFLRYNA-------FVWSTAAI 334
              :||......|||.:|:..|:.:.....:.:|..:...:.:.|...|.:       .|..:|||
Zfish   907 PIVCSVIAGVLHFFFLAAFSWMCLEGVQLFLMLVEVFESEFSRRKYYYASGYLFPCVVVGISAAI 971

  Fly   335 MTGSIYIVNQIWENDPSKWNWLPLVGFIRCSVKDWHPSVWIYISGPSLALSTFNVAMFALTAIYI 399
            ...|.         ...|..||.:         |.| .:|.:| ||...:...|: :|.:..:|
Zfish   972 DYKSY---------GTKKACWLRV---------DNH-FIWSFI-GPVTFIILLNL-IFLVVTMY- 1014

  Fly   400 RKVKGGINKFTNEEEGRINCINFDSQTYLQFLRLSIVMGLTWIFNVIPYSARLHIFWEWVGIISE 464
            :.||..::  ...:..|:..|.  |..:..|..|.::. |||.|.:        :|.....:|..
Zfish  1015 KMVKHSMS--MKPDSSRLESIR--SWVFGAFALLCLLC-LTWSFGL--------LFLNDSSVIMA 1066

  Fly   465 YFHSAF----GIVLFV 476
            |..|.|    |:.:||
Zfish  1067 YLFSIFNTLQGMFIFV 1082

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mthl7	NP_648181.2	Mth_Ecto	27..214	CDD:448329	20/116 (17%)
		7tmB3_Methuselah-like	226..489	CDD:410632	60/277 (22%)
		TM helix 2	251..271	CDD:410632	6/19 (32%)
		TM helix 3	281..308	CDD:410632	6/26 (23%)
		TM helix 4	321..341	CDD:410632	6/26 (23%)
		TM helix 5	369..399	CDD:410632	7/29 (24%)
		TM helix 6	422..449	CDD:410632	7/26 (27%)
		TM helix 7	457..482	CDD:410632	7/24 (29%)
adgrl2b.1	XP_073767727.1	None