Protein Alignment mthl7 and adgre14

DIOPT Version :10

• Sequence 1: NP_648181.2
• Gene: mthl7 / 38910
• FlyBaseID: FBgn0035847
• Length: 491
• Species: Drosophila melanogaster
• Sequence 2: XP_021330419.2
• Gene: adgre14 / 108182849
• ZFINID: ZDB-GENE-131120-49
• Length: 688
• Species: Danio rerio
• Alignment Length: 294
• Identity: 55/294 - (18%)
• Similarity: 103/294 - (35%)
• Gaps: 92/294 - (31%)

  Fly   203 FPKSMWIIRHRCTSHISPGSLEILIITMICFVLTIAVYLYI---KKLRNVTGKCIVCCIVS---- 260
            |.:..|          |||...:..|. ||..|.:|..|::   :.|..:..:.::|.::|
Zfish   422 FTRCQW----------SPGVNNVARIN-ICISLLLAHLLFLLTQQFLSLIRRQKVLCMLISGLLH 475

  Fly   261 ---------RFIQCLIMILDHLNLLNGICSPAGYSSHFFRMASNLWLSVISYHTWKVLTSLNRVD 316
                     .||:.:::.:...||       :..||....:..|..|.||.|....|:.|:
Zfish   476 FLFLSGFVWMFIEAVLLFICVKNL-------SQISSQMKNVLRNKLLCVIGYAVALVVVSI---- 529

  Fly   317 PNYRFLRYNAFVWSTAAIMTGSIYIVNQIWENDPSKWNWLPLVGFIRCSVKDWHPSVWIYISGPS 381
                         |.|.:..|                     .|..:|.::.....:|.:: ||.
Zfish   530 -------------SAAVVPNG---------------------YGSEKCWIQMHKGFIWSFL-GPV 559

  Fly   382 LALSTFNVAMFALTAIYIRKVKGGINKFTNEEEGRIN---CINFDSQTYLQFLRLSIVMGLTWIF 443
            ..:...||.:|.....   .:|....|. |.:..::|   .:.|  :|..||    :|:|.:||.
Zfish   560 TIIIALNVILFISIGF---SLKSAFKKL-NADVSQLNQTKIVMF--KTLAQF----VVLGCSWIL 614

  Fly   444 NVIPYSARLHIFWEWVGIISEYFHSAFGIVLFVL 477
            .....|:::      :.|:....:|..|..:|::
Zfish   615 GFFTNSSKV------LEILFLILNSQQGTFIFLI 642

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mthl7	NP_648181.2	Mth_Ecto	27..214	CDD:448329	2/10 (20%)
		7tmB3_Methuselah-like	226..489	CDD:410632	50/271 (18%)
		TM helix 2	251..271	CDD:410632	4/32 (13%)
		TM helix 3	281..308	CDD:410632	7/26 (27%)
		TM helix 4	321..341	CDD:410632	3/19 (16%)
		TM helix 5	369..399	CDD:410632	6/29 (21%)
		TM helix 6	422..449	CDD:410632	8/26 (31%)
		TM helix 7	457..482	CDD:410632	4/21 (19%)
adgre14	XP_021330419.2	None