DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mthl7 and adgrf11

DIOPT Version :9

Sequence 1:	NP_648181.2	Gene:	mthl7 / 38910	FlyBaseID:	FBgn0035847	Length:	491	Species:	Drosophila melanogaster
Sequence 2:	XP_005160858.1	Gene:	adgrf11 / 100537132	ZFINID:	ZDB-GENE-121214-165	Length:	691	Species:	Danio rerio

Alignment Length:	323	Identity:	65/323 - (20%)
Similarity:	121/323 - (37%)	Gaps:	75/323 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   188 EKQD--YCLYRHNFDSDFPKSMWIIRHRCTSHISPGSLEILIITM-ICFVLTIAVYLYIKK---- 245
            ||.|  .|...|........|.:.|..:...:|:...|.|.:::: |..::...|:..:.|
Zfish   345 EKIDKITCECNHTTSFSLLMSPFFIDDKALDYITYTGLGISVLSLVISLIIGAIVWTTVTKSNSA 409

  Fly   246 -LRNVTGKCIVCCIVSRFIQCLIMILDHLNLLNGICSPAG------YSSHFFRMASNLWLSV--- 300
             ||:|   |:|...||..:..:..|:....:..|..:|.|      :|.|.|.:|...|:.:
Zfish   410 YLRHV---CLVNTNVSLLVADVCFIIGASIVQPGQLAPVGPCTAVAFSMHLFFLAFFFWMLISAM 471

  Fly   301 -ISYHTWKVLTSLNRVD--PNYRFLRYNA------FVWSTAAIMTGSIYIVNQIWEN-DPSKWNW 355
             :.|.|..|.:.::|..  ....||.|.|      ..:...|.....|...:..|.| |.:|
Zfish   472 LLLYMTTMVYSQMSRAKMMAIAFFLGYGAPLLIVVITYGLTAREGKYILEADVCWLNFDETK--- 533

  Fly   356 LPLVGFIRCSVKDWHPSVWIYISGPSLALSTFNVAMFALTAIY----IRKVKGGINKFTN--EEE 414
                            ::.|::|..| :.:..|| :..:..:|    :||.:   ||.||  ...
Zfish   534 ----------------ALQIFVSLAS-SFTAVNV-LIIIVVLYKMLIVRKQQ---NKETNILPTV 577

  Fly   415 GRINCINFDSQTYLQFLRLSIVMGLTW---IFNVIPYSARLHIFWEWVGIISEYFHSAFGIVL 474
            .|:            .|.:|.:.|:||   |..::.....:|:.:..:..:...|:...|:::
Zfish   578 TRV------------VLIVSPLFGVTWGLGIGTMLSPDYGIHLVFTILNSLQGIFNLVSGLLV 628

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mthl7	NP_648181.2	Mth_Ecto	27..214	CDD:299804	7/27 (26%)
adgrf11	XP_005160858.1	GAIN	143..>227	CDD:293098
		GPS	318..363	CDD:280071	5/17 (29%)
		7tm_4	374..620	CDD:304433	56/284 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4193
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810