Protein Alignment mthl7 and adgre15

DIOPT Version :10

• Sequence 1: NP_648181.2
• Gene: mthl7 / 38910
• FlyBaseID: FBgn0035847
• Length: 491
• Species: Drosophila melanogaster
• Sequence 2: XP_021333205.2
• Gene: adgre15 / 100536619
• ZFINID: ZDB-GENE-121214-33
• Length: 857
• Species: Danio rerio
• Alignment Length: 287
• Identity: 58/287 - (20%)
• Similarity: 104/287 - (36%)
• Gaps: 77/287 - (26%)

  Fly   255 VCCIVSRFIQCLIMIL-------DHLNLLNGICSPAGYSSHFFRMA------------------S 294
            ||..|......|||..       |.|.||..:|...|..  ||.:|                  .
Zfish   561 VCSCVHLSTFALIMQTSSSPPPSDLLELLGLVCVIVGLV--FFSLALLSFALCQWSPGVNNVARI 623

  Fly   295 NLWLSVISYHTWKVLTS--LNRVDPN----------YRFLRYNAFVWS--TAAIMTGSIYIVNQI 345
            |:.:|::|.|...:||.  |:.:.|.          ..||..:||||.  .|.::...:..::||
Zfish   624 NICISLLSAHLLFLLTQQFLSLIRPQQVLCVAIAGLLHFLFLSAFVWMFIEAVLLFICVKNLSQI 688

  Fly   346 --WENDPSKWNWLPLVGFI--------------------RCSVKDWHPSVWIYISGPSLALSTFN 388
              .:.:.....:|.::|::                    .|.:|.....:|.:: ||...:...|
Zfish   689 SSKKREVLSSGFLCVIGYVLAMVVVCVSIGLVPEGYGSEHCWIKTDEGFIWSFL-GPVCVILALN 752

  Fly   389 VAMFALTAIYIRKVKGGINKFTNEEEGRINCINFDSQTYLQFLRLSIVMGLTWIFNVIPYSARLH 453
            :.:|....|.:......:|...::.: :...:.|  :|..||    :|:|..||.......:
Zfish   753 LILFFKIVITLNSTLKNLNAEVSQMK-QTKVMVF--KTLGQF----VVLGCPWILGFFTNGS--- 807

  Fly   454 IFWEWVGIISEYFHSAFGIVLFVLLVL 480
               |.:.|:...|:|..|..:|::..|
Zfish   808 ---EVLEIVFLIFNSQQGTFIFLIYCL 831

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mthl7	NP_648181.2	Mth_Ecto	27..214	CDD:448329
		7tmB3_Methuselah-like	226..489	CDD:410632	58/287 (20%)
		TM helix 2	251..271	CDD:410632	6/22 (27%)
		TM helix 3	281..308	CDD:410632	8/44 (18%)
		TM helix 4	321..341	CDD:410632	7/21 (33%)
		TM helix 5	369..399	CDD:410632	6/29 (21%)
		TM helix 6	422..449	CDD:410632	8/26 (31%)
		TM helix 7	457..482	CDD:410632	7/24 (29%)
adgre15	XP_021333205.2	None