DRSC/TRiP Functional Genomics Resources

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Protein Alignment mthl7 and adgre15

DIOPT Version :9

Sequence 1:NP_648181.2 Gene:mthl7 / 38910 FlyBaseID:FBgn0035847 Length:491 Species:Drosophila melanogaster
Sequence 2:XP_021333205.1 Gene:adgre15 / 100536619 ZFINID:ZDB-GENE-121214-33 Length:543 Species:Danio rerio


Alignment Length:287 Identity:58/287 - (20%)
Similarity:104/287 - (36%) Gaps:77/287 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly   255 VCCIVSRFIQCLIMIL-------DHLNLLNGICSPAGYSSHFFRMA------------------S 294
            ||..|......|||..       |.|.||..:|...|..  ||.:|                  .
Zfish   247 VCSCVHLSTFALIMQTSSSPPPSDLLELLGLVCVIVGLV--FFSLALLSFALCQWSPGVNNVARI 309

  Fly   295 NLWLSVISYHTWKVLTS--LNRVDPN----------YRFLRYNAFVWS--TAAIMTGSIYIVNQI 345
            |:.:|::|.|...:||.  |:.:.|.          ..||..:||||.  .|.::...:..::||
Zfish   310 NICISLLSAHLLFLLTQQFLSLIRPQQVLCVAIAGLLHFLFLSAFVWMFIEAVLLFICVKNLSQI 374

  Fly   346 --WENDPSKWNWLPLVGFI--------------------RCSVKDWHPSVWIYISGPSLALSTFN 388
              .:.:.....:|.::|::                    .|.:|.....:|.:: ||...:...|
Zfish   375 SSKKREVLSSGFLCVIGYVLAMVVVCVSIGLVPEGYGSEHCWIKTDEGFIWSFL-GPVCVILALN 438

  Fly   389 VAMFALTAIYIRKVKGGINKFTNEEEGRINCINFDSQTYLQFLRLSIVMGLTWIFNVIPYSARLH 453
            :.:|....|.:......:|...::.: :...:.|  :|..||    :|:|..||.......:   
Zfish   439 LILFFKIVITLNSTLKNLNAEVSQMK-QTKVMVF--KTLGQF----VVLGCPWILGFFTNGS--- 493

  Fly   454 IFWEWVGIISEYFHSAFGIVLFVLLVL 480
               |.:.|:...|:|..|..:|::..|
Zfish   494 ---EVLEIVFLIFNSQQGTFIFLIYCL 517

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
mthl7NP_648181.2 Mth_Ecto 27..214 CDD:299804
adgre15XP_021333205.1 GPS 219..265 CDD:197639 6/17 (35%)
7tm_GPCRs 272..531 CDD:333717 51/262 (19%)
TM helix 1 272..296 CDD:320095 8/25 (32%)
TM helix 2 305..326 CDD:320095 5/20 (25%)
TM helix 3 340..362 CDD:320095 6/21 (29%)
TM helix 4 386..402 CDD:320095 2/15 (13%)
TM helix 5 420..443 CDD:320095 4/23 (17%)
TM helix 6 467..492 CDD:320095 8/30 (27%)
TM helix 7 494..519 CDD:320095 7/24 (29%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4193
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.810

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