DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Nmt and NMT1

DIOPT Version :9

Sequence 1:	NP_523969.1	Gene:	Nmt / 38909	FlyBaseID:	FBgn0020392	Length:	472	Species:	Drosophila melanogaster
Sequence 2:	NP_568846.1	Gene:	NMT1 / 835805	AraportID:	AT5G57020	Length:	434	Species:	Arabidopsis thaliana

Alignment Length:	441	Identity:	211/441 - (47%)
Similarity:	300/441 - (68%)	Gaps:	28/441 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 DAEQPDGA---KNEASVSAN------ASKQALLQAVSDAMASTRQMAKKFAFWSTQPV------- 99
            |...|.|:   |.:..|.||      .|.:.:::...|:|:.    ||...||.||||
plant     3 DNNSPPGSVEQKADQIVEANPLVKDDTSLETIVRRFQDSMSE----AKTHKFWETQPVGQFKDIG 63

  Fly   100 -TKLDEQVTTNECIEPNKEISEIRALPYTLPGGFKWVTLDLNDANDLKELYTLLNENYVEDDDAM 163
             |.|.|..     |||...:||::..||.||..::|.|.|:|..:...|:|.||..||||||:.|
plant    64 DTSLPEGP-----IEPATPLSEVKQEPYNLPSVYEWTTCDMNSDDMCSEVYNLLKNNYVEDDENM 123

  Fly   164 FRFDYQPEFLKWSLQPPGWKRDWHVGVRVEKSGKLVGFISAIPSKLKSYDKVLKVVDINFLCVHK 228
            |||:|..|||:|:|:|||:.:.||:|||.:.|.|||.|||.:|::::..|:|:|:.:||||||||
plant   124 FRFNYSKEFLRWALRPPGYYQSWHIGVRAKTSKKLVAFISGVPARIRVRDEVVKMAEINFLCVHK 188

  Fly   229 KLRSKRVAPVLIREITRRVNLTGIFQAAYTAGVVLPTPVATCRYWHRSLNPKKLVDVRFSHLARN 293
            ||||||:|||:|:|:||||:|..|:||||||||:||||:.||:|||||||||||:||.||.|...
plant   189 KLRSKRLAPVMIKEVTRRVHLENIWQAAYTAGVILPTPITTCQYWHRSLNPKKLIDVGFSRLGAR 253

  Fly   294 MTMQRTMKLYKLPDQPKTKGYRRITAKDMDKAHKLLEDYLKRFQLSPVFSKEEFRHWFTPKEGII 358
            |||.||:|||||||.|.|.|:|::..:|:....:||.:||.:|.::..|.:.:..||..|:|.::
plant   254 MTMSRTIKLYKLPDAPITPGFRKMEPRDVPAVTRLLRNYLSQFGVATDFDENDVEHWLLPREDVV 318

  Fly   359 DCFVV-ADEKGNITDLTSYYCLPSSVMHHPVHKTVRAAYSFYNVSTKTPWLDLMNDALISARNVQ 422
            |.::| :.|..::||..|:|.|||:::.:|.:.|::||||:|||:|:|.:|.|||||||.::...
plant   319 DSYLVESPETHDVTDFCSFYTLPSTILGNPNYTTLKAAYSYYNVATQTSFLQLMNDALIVSKQKG 383

  Fly   423 MDVYNALDLMENKKYFAPLKFGAGDGNLQYYLYNWRCPS-MQPEEIALILM 472
            .||:||||:|.|:.:...||||.|||.|.|||||:|..| ::|.|:.|:|:
plant   384 FDVFNALDVMHNESFLKELKFGPGDGQLHYYLYNYRLKSALKPAELGLVLL 434

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nmt	NP_523969.1	NMT	112..268	CDD:279562	89/155 (57%)
Nmt	NP_523969.1	NMT_C	284..459	CDD:280893	82/175 (47%)
NMT1	NP_568846.1	NMT1	24..421	CDD:227423	199/405 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	208	1.000	Domainoid score	I811
eggNOG	1	0.900	-	-		E1_COG5092
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H69027
Inparanoid	1	1.050	429	1.000	Inparanoid score	I418
OMA	1	1.010	-	-		QHG53825
OrthoDB	1	1.010	-	-		D1025421at2759
OrthoFinder	1	1.000	-	-		FOG0002110
OrthoInspector	1	1.000	-	-		otm2870
orthoMCL	1	0.900	-	-		OOG6_101234
Panther	1	1.100	-	-	LDO	PTHR11377
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1227
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.930