DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG13676 and CG13643

DIOPT Version :9

Sequence 1:	NP_648179.3	Gene:	CG13676 / 38906	FlyBaseID:	FBgn0035844	Length:	883	Species:	Drosophila melanogaster
Sequence 2:	NP_001262937.1	Gene:	CG13643 / 50074	FlyBaseID:	FBgn0040601	Length:	819	Species:	Drosophila melanogaster

Alignment Length:	817	Identity:	166/817 - (20%)
Similarity:	260/817 - (31%)	Gaps:	278/817 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   123 MDEIHFKCEGLHD----GFYASIEYKCQIYHHCV----YGIRH-------------DFLCANFTA 166
            |.:..|.|   ||    |:||..|.:||::|.||    .|:.|             .|||.|.||
  Fly    49 MPKTQFTC---HDKILGGYYADPETQCQMFHVCVKLPGVGLLHRRANPFVQQVQDYRFLCPNTTA 110

  Fly   167 FDQRTFICHFASDVDCEGSQKYWNRN--DELYMATTTTSTSTTTTPAPPTLPPAP---------- 219
            |||...||....||||:.:..:::..  ::|| .....|.|.....|...|..|.
  Fly   111 FDQELQICANWLDVDCDKATSFYDNGHLNDLY-RNGDESKSANEEEATFHLQRAETGDIRRSKEN 174

  Fly   220 ---------RRRPQRPQRPLRRPY--------------------NRRPIDDYY------------ 243
                     |...|:|:.  |..|                    .:|||..||
  Fly   175 HNNNNINNNRGADQKPRH--RHNYAQTGGSSSSSSSPKLEITQSTKRPISTYYTPTTLGSTTTST 237

  Fly   244 YEDQDQYEDDYYEERPVRRPKPRPRQRKPQVEPEYDDEY---DDKRTEAKKPIRRNRNRYRDEEE 305
            .......|..||..                   .|::.|   ||.:.:.....:.:.:.:.....
  Fly   238 TSTTTTTERSYYNN-------------------NYNNNYSNNDDSKQDLDDIFKGSHSSHFFSNR 283

  Fly   306 ALDEDYDERPSK-RP----------------RG--KPTAGTAG---------------RKI---- 332
            ....:|||.||: :|                ||  :||:|::.               :||
  Fly   284 HGGREYDEEPSRPKPNDFSDYQRKTTRVTPTRGVQRPTSGSSSPIPSSTAAPSTTKSLKKITLHA 348

  Fly   333 ----------------------SPRKPGRVEERRSFNEDRPLGRRRSE-------------KERT 362
                                  :||....:..|.||..:....:.|.:             |..:
  Fly   349 TFNTDFLDSSSHTKSPSYSAVTTPRPSSSITSRFSFGSNDFSTQERIQPTTYNPNNGAYRFKTTS 413

  Fly   363 TPSSA-------LDDLDEYEKPYNSA--------------------DQVEAAEEQTPQK---VKT 397
            .|:|:       :.|.::..||.::|                    |..::.:.|.||.   .:|
  Fly   414 PPASSTKVTGKGVQDFEKRSKPTSAAVRKQKLGPQESNFINQNEFVDLSKSTKLQQPQPFQVAQT 478

  Fly   398 TPKPLTEFITPKAAAASVYARPRAPPRIARPVPINEKKKFSYPVQKITATTQAPSNSAQEEEDYP 462
            .|..|...          |.|.:  |::.| |...|...||.|..|..:.|   |..:...:...
  Fly   479 KPNQLEPH----------YQRHK--PQVTR-VGGQEPAPFSAPSSKPRSFT---SRGSITYKATT 527

  Fly   463 EEQVEEDYEQPPARNTPRRRTPASRAEQKPTRTTLRKPVTDKKPVDEEYDEPAEPEPLRKRKRPL 527
            |..|:::...|...:|       :||::..|.||.| |.|.|||.::.|.......|.:...:..
  Fly   528 ERYVDQELYYPTTSST-------TRAKEAYTPTTFR-PTTYKKPYEQSYQSQQTHRPTQAATKKA 584

  Fly   528 A-------PRSRVPAADVDFEDEEYE----ESPAPVSTAAPLRNQRLRAKT-TTRKPTAPPRPRK 580
            |       |.:..|.|:||.:|.:|.    |:..|.:....|||:...:.| ||..|....|...
  Fly   585 AHSVTSAPPTTTNPHANVDEDDGQYHPELYENDFPRNRIRFLRNRSTSSTTSTTSAPVVSSRQPH 649

  Fly   581 PIVEDEEELEHPVEAV---EDEAPAPRSRANSLSGR----------NAGAGFSQRPSSVRVVKRP 632
            ...:....|:...::|   |.|....|.|.:.||..          |.||. |.......:.|..
  Fly   650 GFQQAHHHLKSQQQSVYQKERERERERERESDLSDEDELFKTAQSLNFGAA-SINKLRADIYKAE 713

  Fly   633 FLPSRGGSPYLPRGLQPVGVALKPLPTTDSTPIDMGSTISGVRLLEHGAPLLRGNPDSGEDDEED 697
            ....:..|.|.|:.......:.....:|.:|.....:|.:..|
  Fly   714 KTSQQYNSQYSPQLASSPQASSSSSSSTSTTSTTTSTTTTTTR---------------------- 756

  Fly   698 APPSPSPPRTTLPPRSALPA-TPKRVEPQRPKLNLDE 733
            .||:.....||....||.|. |.|.|:.::.:..|::
  Fly   757 RPPTTVRTTTTTFTTSAPPVETKKSVKSKKEQQQLEK 793

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13676	NP_648179.3	CBM_14	130..182	CDD:279884	27/72 (38%)
CG13643	NP_001262937.1	CBM_14	63..126	CDD:279884	24/62 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR22933
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010