DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG13676 and CG14880

DIOPT Version :9

Sequence 1:	NP_648179.3	Gene:	CG13676 / 38906	FlyBaseID:	FBgn0035844	Length:	883	Species:	Drosophila melanogaster
Sequence 2:	NP_650538.1	Gene:	CG14880 / 41986	FlyBaseID:	FBgn0038422	Length:	637	Species:	Drosophila melanogaster

Alignment Length:	791	Identity:	161/791 - (20%)
Similarity:	234/791 - (29%)	Gaps:	302/791 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly   128 FKCEGLHDGFYASIEYKCQIYHHC-VYGIRHDFLCANFTAFDQRTFICHFASDVDCEGSQKYWNR 191
            |.|.|...|:||.:|..||:||.| ..|.:..:.|.|.|.|.||..||.....|:|..::..:..
  Fly    49 FSCAGRPAGYYADVETGCQVYHMCDGLGRQFSYTCPNTTLFQQRMLICDHWYMVNCSKAESNYAA 113

  Fly   192 N------DELYMATTTTSTSTTTTPAPPTLPPAPRRRPQRPQ---RPLRRPYNRRPIDDYYYEDQ 247
            |      |:.::   ....::..||.|..|.     ||..|.   ...|..|.:      :..:|
  Fly   114 NLLIGQRDKPFV---NDEENSLRTPRPDLLD-----RPYAPDYSGESFRSQYKQ------FTSNQ 164

  Fly   248 DQYEDDYYEERPVRRPKPR--------PRQRKPQVEPEYDDEYDDKRTEAKKP----IRRNRNRY 300
            :|..|:..:.....:..|:        |...:..:.|.|:.:.:....::.||    |.......
  Fly   165 NQIRDESVKGAGAGKSDPQISQTRWRIPPPSRTILPPAYEPQIELPSAQSAKPRIPIITSTTTTT 229

  Fly   301 RDEEEALDEDYDERPSKRPRGKPTAGTAGRKISPRKPGRVEERRSFNEDRPLGRRRSEKERTTPS 365
            |.....       ||:...|...|..|     :.|.|.....:.:.:..||..:...
  Fly   230 RATTTT-------RPTTTTRATTTTTT-----TRRPPVTARPKEALHNRRPNFQEHD-------- 274

  Fly   366 SALDDL-DEYEKPYNSADQVEAAEEQTPQKVKTTPKPLTEFITPKAAAASVYARPRAPPRIARPV 429
              :||| ..:...||::....:||... ::.|.:...||:||.|             |.:|..|
  Fly   275 --MDDLGTSHSTRYNTSADFNSAESPL-RETKQSSTKLTKFIKP-------------PSKIYEP- 322

  Fly   430 PINEKKKFSYPVQKI---------TATTQAPSNSAQEEEDYPEEQVEEDYEQPPARNTPRRRTPA 485
                  .|.||:..:         .|||...|.:|........::|.....:|.:|.|.....|.
  Fly   323 ------PFVYPIYNLEESQTQNAAVATTLRTSTAAPFSPVPSRKEVSTTTPRPLSRPTTLAGVPF 381

  Fly   486 SRAEQKPTRTTLRKPVTDKKPVDEEYDEPAEPEPLRKRKRPLAPRS--RVPAADVDFEDEEYEES 548
            |.|....|.||:..|                            |||  |.||....|      ..
  Fly   382 SSATHPTTVTTVGVP----------------------------PRSDNRTPAPAQSF------RL 412

  Fly   549 PAPVSTAAPLRNQRLRAKTTTRKPTAPPRPRKPIVEDEEELEHPVEAVEDEAPAPRSRANSLSGR 613
            ..|.|||||                 |.||
  Fly   413 ATPTSTAAP-----------------PSRP----------------------------------- 425

  Fly   614 NAGAGFSQRPSSVRVVKRPFLPSRGGSPYLPRGLQPVGVALKPLPTTDSTPIDMGSTISGVRLLE 678
                           .:.||      :..||             |..|..|.|:.:|
  Fly   426 ---------------AQLPF------NDLLP-------------PFVDFVPHDIATT-------- 448

  Fly   679 HGAPLLR--GNPDSGEDDEEDAPPSPSPPRTTLPPRSALPATPKRVEPQRPKLNLDELYENDYDV 741
            .|.|:..  ..|.:|.:     ||...||          .....|..|:.         ..||.|
  Fly   449 QGPPIYYEWKVPSNGLE-----PPKLDPP----------IGVDGREYPET---------TGDYGV 489

  Fly   742 T---------LNDALDPTLKPL---SPQHPHPHSHQLPYQQQQQQSQRQYASAYNPFAYQPAYQS 794
            |         |||......||:   ||......||:|...:..:..:.|
  Fly   490 TSKQDVFNTRLNDIGSHQKKPVQITSPLQQSSTSHRLAISRSIKPKEEQ---------------- 538

  Fly   795 PTSASASAPASASQAASYHSDSYFSSTDI---RRRAIVPAQTARPHRLEYA----AAGGAAGGPS 852
                         ::|...||...|||||   |::.::|         |||    ..|....||.
  Fly   539 -------------ESAQRRSDVVASSTDISHLRKQFLIP---------EYAFPLETIGRTGYGPG 581

  Fly   853 SGGAVSGSGVS 863
            :|.|..|||.|
  Fly   582 AGAAAGGSGSS 592

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13676	NP_648179.3	CBM_14	130..182	CDD:279884	21/52 (40%)
CG14880	NP_650538.1	CBM_14	51..104	CDD:279884	21/52 (40%)
CG14880	NP_650538.1	COG3979	336..>457	CDD:226487	43/248 (17%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR22933
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010