DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13676 and Y56A3A.6

DIOPT Version :9

Sequence 1:	NP_648179.3	Gene:	CG13676 / 38906	FlyBaseID:	FBgn0035844	Length:	883	Species:	Drosophila melanogaster
Sequence 2:	NP_499539.1	Gene:	Y56A3A.6 / 176618	WormBaseID:	WBGene00013227	Length:	798	Species:	Caenorhabditis elegans

Alignment Length:	803	Identity:	186/803 - (23%)
Similarity:	279/803 - (34%)	Gaps:	236/803 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 SIAKTPVSTSSTTSTTTEAPAVEEEEVEEEQPVPTADSSDGSKSDNGTLLKNSKLTGIPQIDYIW 98
            |:..||||...      |:|.|:::..:...|.|....:..:.:.     .:.|....||
Worm   109 SVISTPVSQYD------ESPIVQKQRTKRAAPPPPPPPAAAAAAP-----ISPKAAPTPQ----- 157

  Fly    99 DPNLPRELRGY-NLSTYPFLSTVPPMDEIHFKCE-GL-HDGFYASIEYKCQIYHHCVY----GIR 156
            .| .|..:..| ..||....||:||....|.|.| |: ::..|.|:..|...::....    .||
Worm   158 SP-APNRVPHYRQTSTASVSSTIPPPPPPHRKQENGIDYEAMYKSLLTKFDEWNQMKLADGGSIR 221

  Fly   157 HDFLCANFTAFDQRTFIC---HFASDVDCEGSQKYWNRNDELYMATTTTSTSTTTTPAPPTLPPA 218
            .:.:.|......:|..:.   ...||:...||            |::.:|:|:...      ...
Worm   222 EERMKAEVLKEHERLKMLLDNQITSDLPKTGS------------ASSQSSSSSGNN------NHN 268

  Fly   219 PRRRPQRPQRPLRRPYNRRPIDDYYYEDQDQYEDDYYEERPVRRPKPRPRQRKPQVEPE------ 277
            ......:.|.||:.|               ||.:.|      .:|....:.|.|.|.|:
Worm   269 NNNNNVKKQLPLKIP---------------QYGNFY------SQPSQPAQNRSPPVAPQAAPGGT 312

  Fly   278 -YDDEYDDKRTEAKK-----PIRRNRNRYRDEEEALDEDYDER-----PSKRPRGKPTAGTAGRK 331
             |      |||..:|     |: .|.|       .:....||.     .|..|:..|:..|..
Worm   313 VY------KRTSREKLSPKSPV-PNGN-------IISPKTDENRNIVVTSASPKNPPSQNTVA-- 361

  Fly   332 ISPRKPGRVEERRSFNEDRPLGRRRSEKERTTPSSALDDLDEYEKPYNSADQVEAAEEQTPQKVK 396
             ..|....|||           :|:.|||          :.:|..|       .|.|.|...: |
Worm   362 -VDRLRREVEE-----------QRQREKE----------VKQYRNP-------RALESQASPR-K 396

  Fly   397 TTPKP-LTEFITPKAAAA---SVYARPRAPPRIARPVPINEKKKFSYPVQKITATTQAPSNSAQE 457
            ::|.| :.|:...|:...   .||      ..||.|:|.|...|.| ..:|...|..||...:..
Worm   397 SSPGPRMVEYKAMKSPGLEPDGVY------EEIAPPIPKNPPPKLS-DYRKEQQTVVAPRMPSVP 454

  Fly   458 EEDYPEEQVEEDYEQP----PARNTPRRRTPASRAEQKPTRTTLRKPVTDKK-----PVDEE--- 510
            ...|...|:......|    |.:.:|   ||.:..|...:...|||.....|     ||.||
Worm   455 TNGYVRLQMNGKKPAPVTPHPVKLSP---TPYTGPEYSSSPKLLRKTPEPAKIYSSVPVKEEKKV 516

  Fly   511 YDEP-AEPEPLRKRKRPLAPRSRVPAADVDFEDEEYEES------PAPVS--------------- 553
            |::| |.|:        :|| ..|.||.||.....|:.|      |.|||
Worm   517 YEKPQAHPQ--------IAP-PMVRAASVDQNGNNYQRSKPVEVKPRPVSSPLMIRAASVDQNPM 572

  Fly   554 TAAP--LRNQRLRA---KTTTRK--PTAPPRPRKPIVEDE-------EELEHPVEAVEDEAPAPR 604
            ||:|  :|..::.|   ..:.||  ||:|...|:|:...|       .::..||:.|...|| |.
Worm   573 TASPSVIRKSQVTATQSPVSYRKIPPTSPTPQRRPLNNTEVPSPVTYRKISAPVQKVTSPAP-PA 636

  Fly   605 SRANSL-----SGRNAGAGFSQRPSSVRVVKRPFLPSRGGSPYLPRG-LQPVGVALKP------- 656
            :|:.|.     :.|.:..|.....||...|.   :.|....|| |:| :.|..:::||
Worm   637 ARSVSTDQPPPANRRSQVGILSATSSKATVT---VTSATSPPY-PKGSVGPTVISIKPAPVQQAP 697

  Fly   657 -----LPTTDSTPIDMGSTISGVRLLEHGAPLLRGNPDSGEDDE---------EDAPPSPSPPRT 707
                 .||...|..|:...:.|.:|.:.|.|..:.....|:..|         ...||.|.||
Worm   698 MAPRAAPTKVDTSFDISDVLKGPKLRKVGMPAEKSGISLGKVVESVEASGNRPSSTPPPPPPP-- 760

  Fly   708 TLPPRSALPATPKRVEPQRPKLN 730
              ||.:|.|..||..:.:...:|
Worm   761 --PPLAAAPPQPKNPDLRDSLMN 781

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13676	NP_648179.3	CBM_14	130..182	CDD:279884	11/60 (18%)
Y56A3A.6	NP_499539.1	PHA03247	<448..704	CDD:223021	68/272 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22933
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100