Protein Alignment mus301 and Polg

DIOPT Version :10

• Sequence 1: NP_648178.1
• Gene: mus301 / 38905
• FlyBaseID: FBgn0002899
• Length: 1051
• Species: Drosophila melanogaster
• Sequence 2: XP_008757783.1
• Gene: Polg / 85472
• RGDID: 620057
• Length: 1223
• Species: Rattus norvegicus
• Alignment Length: 679
• Identity: 132/679 - (19%)
• Similarity: 213/679 - (31%)
• Gaps: 232/679 - (34%)

  Fly   468 AGQTLEEIFVPSRSVEYNYSEAVKRADPDHLAGLISECAPEHCCLVF----CPSRKNCENVALLL 528
            |..:|.|..:|.:..::.::|...|..|:..|..::  .||...|||    |.:...|..:|:.:
  Rat   136 AAASLSEAQLPPQPRKWVWAEGWTRYGPEGEAEPVA--IPEERALVFDVEVCLAEGTCPTLAVAI 198

  Fly   529 SRIVP-------KHKFFEHRRSEKLDLMDALDKMCGILSPVLAKTLPYGIAYHHSGLTTDERKYI 586
            |   |       ..:..|.|.|           ....|||  |..:|.|::...|..|..:.:
  Rat   199 S---PSAWYSWCSRRLVEERYS-----------WTSQLSP--ADLIPLGVSASASSSTQQDWQ-- 245

  Fly   587 ETAYRFGVVTVICCTSTLAAGVNLPAKRVIIRAPYVGQ----EFLT----------LCKYKQMVG 637
                           ..|..|.|:...|..||..|:.|    .||.          |..:::.:.
  Rat   246 ---------------EQLVVGHNVSFDRAHIREQYLIQGSRMRFLDTMSMHMAISGLSSFQRSLW 295

  Fly   638 RAGRAGLGEAGESILIAQSKDNLLVGQMLFSPMDKALSSLDQNEAVGLQSLILSVVGLNLAECRR 702
            ...:.|..:........|.......|        .|:||.|..:.....         |||:..
  Rat   296 MGAKQGKHKTQHPTKRGQKSQKNANG--------PAISSWDWMDISSAN---------NLADVH- 342

  Fly   703 DLNRLVNSTLLSVQAKSLEVAVNEIVLRILREMFKNKVLQLAEPQAKSKINSSDIITSQDVSQAN 767
              |..|....|:.:.:.|.|..:   :|.:||.|::    |.|..|:      |:..:.:|.|..
  Rat   343 --NLYVGGPRLAKEPRELFVKGS---MRDIRENFQD----LMEYCAR------DVWATFEVFQQQ 392

  Fly   768 RPAGDRRLLIGQSTPFKLTNIGRAAFKAGIDYKRAN---------------AIHKELKQAQQQLI 817
            .|      |..:..|..:|..|  ..:.|:.|...|               .:.:|:|::..:|
  Rat   393 LP------LFLERCPHPVTLAG--MLEMGVSYLPVNQNWERYLTEAQSTYEELQREMKKSLMEL- 448

  Fly   818 LTNYLHLLYLVVCFNSNERGDELFPADASILFGVYT--------SLPLDSQAMFKQLGFTEAHAA 874
                           :|:....|  :..|::..:|.        .|..|.|.      |.:..|.
  Rat   449 ---------------ANDACQLL--SGESLVDWLYRYKEDPWLWDLEWDLQE------FKQKKAK 490

  Fly   875 RLFKTQSVQ-------------------GPLS----LQLN-----RLYKVLILADILNLLP--IP 909
            ::.||.|..                   ||.|    ||.|     ||.::....|:|...|  :|
  Rat   491 KVKKTASASKLPIEGAGPFGDPMDQEDPGPPSEEEELQQNIMAHTRLQQLKSTTDLLPKRPQHLP 555

  Fly   910 SVASKYNVERGTLQHLISQSTAAASAIVRLCEELEE-FWCYKP----LFERI------------- 956
            .....|.                     :||..|:: .|...|    |..|:
  Rat   556 GHPGWYR---------------------KLCPRLDDPAWTPGPSLLSLQMRVTPKLMALTWDGFP 599

  Fly   957 LHKMDRCGTFELEP-----LMELPAVKINRARQLYAAGFQTIGDIARVRPSHLV----QSLEHMP 1012
            ||..|..|...|.|     |.||| |............::.|..:.|   .|.:    |.||...
  Rat   600 LHYSDSHGWGYLVPGRRDNLTELP-VSPTEESAAVTCPYRAIESLYR---RHCLDQGKQQLETQE 660

  Fly  1013 LRVATE--IVSAAKIILMKKLDHLEEETE 1039
            ..:|.|  :..:|....:::|..|:.|.|
  Rat   661 TDLAEEFLLTDSAMWQTVEELGCLDVEAE 689

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mus301	NP_648178.1	DEXHc_POLQ-like	247..449	CDD:350784
		BRR2	255..828	CDD:440817	76/399 (19%)
Polg	XP_008757783.1	DNApol_Exo	104..396	CDD:465664	66/333 (20%)
		DNA_pol_A	413..>455	CDD:470638	7/57 (12%)
		DNA_pol_gammaA	772..1187	CDD:176478