Protein Alignment mus301 and MIP1

DIOPT Version :9

• Sequence 1: NP_648178.1
• Gene: mus301 / 38905
• FlyBaseID: FBgn0002899
• Length: 1051
• Species: Drosophila melanogaster
• Sequence 2: NP_014975.2
• Gene: MIP1 / 854508
• SGDID: S000005857
• Length: 1254
• Species: Saccharomyces cerevisiae
• Alignment Length: 831
• Identity: 159/831 - (19%)
• Similarity: 261/831 - (31%)
• Gaps: 277/831 - (33%)

  Fly   139 AEMEDIFH---GADDFSDPMVQNTQLFLDAMTFKKPKTPEKLLAPL---KDDSMSFIS---KSVI 194
            ||:|...|   ..:|:.||       :|:.......|...|....:   |.|...|.|   .::|
Yeast   277 AEVESEVHPEISIEDYDDP-------WLNVSALNSLKDVAKFHCKIDLDKTDRDFFASTDKSTII 334

  Fly   195 EGLVQGTQYVTCEELKNQSLLDPVNWETQAFADFEKNNQDIDKFPSKGEFYGLPDKVKKMILEHK 259
            |...:...|...:......:.|.:      |..|.|      |.|....|.|| ..:.|.||..|
Yeast   335 ENFQKLVNYCATDVTATSQVFDEI------FPVFLK------KCPHPVSFAGL-KSLSKCILPTK 386

  Fly   260 GINSLYEWQDECLNLPAIRQRKNLIYALPTSGGKTLVAEILMLRELLCRERNVLFILPYVSIVQE 324
                |.:|.|...:..::.|:..:              :|         |..::.|:..:.::::
Yeast   387 ----LNDWNDYLNSSESLYQQSKV--------------QI---------ESKIVQIIKDIVLLKD 424

  Fly   325 KVS--AMSPFAIDLDFIVEEYTAGK----GKCPPQPRRKR--RSLFIA--SIEKGAVLMDSLIDV 379
            |..  ...|:...||:..:.....|    .||...|....  |.||.:  ::|....:...:|.:
Yeast   425 KPDFYLKDPWLSQLDWTTKPLRLTKKGVPAKCQKLPGFPEWYRQLFPSKDTVEPKITIKSRIIPI 489

  Fly   380 ---------------------QRPHE-------IGLVVVDELHLIGEKGRGATLEAFLTKVMFL- 415
                                 ..|||       ...|:.|.:....|:.|...|....|.|:|.
Yeast   490 LFKLSWENSPVIWSKESGWCFNVPHEQVETYKAKNYVLADSVSQEEEEIRTHNLGLQCTGVLFKV 554

  Fly   416 -NANIQIVGMSATIGNLSEISSFLNADVYTRGFRPVELKEYIKCGPDLLEINSAGQTLEEIFVPS 479
             :.|    |.:....||...|       |...|....||...:.....|:|||:|.
Yeast   555 PHPN----GPTFNCTNLLTKS-------YNHFFEKGVLKSESELAHQALQINSSGS--------- 599

  Fly   480 RSVEYNYSEAVKRADPDHLAGLISECAPEHCCLVFCPSRKNCENVALLLSRIVPKHKFFEHRRSE 544
                                             .:..:|:..::     ..:||..||  ....:
Yeast   600 ---------------------------------YWMSARERIQS-----QFVVPSCKF--PNEFQ 624

  Fly   545 KLDLMDAL-DKMCGILSPVLAKTLPYGIAYHHSGLTTDERKYIETAYRFGVVTVICCTSTLAAGV 608
            .|....:| ::....|:.::.|.:|.|         |..|:.:|.|:             |.|.
Yeast   625 SLSAKSSLNNEKTNDLAIIIPKIVPMG---------TITRRAVENAW-------------LTAS- 666

  Fly   609 NLPAKRVIIRAPYVGQEFLTLCKYKQMVGRAGRAGLGE--AGESILIAQSKDNLLVGQMLFSPM- 670
            |..|.|       :|.|..|     |:....|...:|.  ..|.:.||.     |||..:|:..
Yeast   667 NAKANR-------IGSELKT-----QVKAPPGYCFVGADVDSEELWIAS-----LVGDSIFNVHG 714

  Fly   671 DKALSSL----DQNEAVGLQSLILSVVGLNLAECRRDLNRLVN------------STLLSVQAKS 719
            ..|:..:    .:||...|.:....::|     |.|:..::.|            |.||.....|
Yeast   715 GTAIGWMCLEGTKNEGTDLHTKTAQILG-----CSRNEAKIFNYGRIYGAGAKFASQLLKRFNPS 774

  Fly   720 LEVAVNEIVLRILREMFKNKVLQLAEPQAKSKI---NSSDIITSQDVSQANRPAGDRRLLIGQST 781
            |   .:|...:|..::::|...:....:...|.   .|..|:.::..|.|.           |.|
Yeast   775 L---TDEETKKIANKLYENTKGKTKRSKLFKKFWYGGSESILFNKLESIAE-----------QET 825

  Fly   782 PFKLTNIGRAAFKAGIDYK------RANAIHKELKQAQQQLILTNYLHLL-----YLVVCFNSNE 835
            | |...:|     .||.|.      |||:..........|....:|||||     |::..:|...
Yeast   826 P-KTPVLG-----CGITYSLMKKNLRANSFLPSRINWAIQSSGVDYLHLLCCSMEYIIKKYNLEA 884

  Fly   836 R---------------GDELFPADASILFGVYTSLPLDSQAMF-KQLGFTE 870
            |               .|:...|.|..:..::|      :||| :|:|..|
Yeast   885 RLCISIHDEIRFLVSEKDKYRAAMALQISNIWT------RAMFCQQMGINE 929

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mus301	NP_648178.1	BRR2	247..998	CDD:224125	134/714 (19%)
		DEXHc_POLQ-like	247..449	CDD:350784	43/241 (18%)
MIP1	NP_014975.2	DNApol_Exo	95..362	CDD:407968	19/97 (20%)
		DNA_pol_gammaA	581..960	CDD:176478	91/469 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0749
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900