Protein Alignment mus301 and AT2G42270

DIOPT Version :10

• Sequence 1: NP_648178.1
• Gene: mus301 / 38905
• FlyBaseID: FBgn0002899
• Length: 1051
• Species: Drosophila melanogaster
• Sequence 2: NP_181756.1
• Gene: AT2G42270 / 818828
• AraportID: AT2G42270
• Length: 2172
• Species: Arabidopsis thaliana
• Alignment Length: 1104
• Identity: 239/1104 - (21%)
• Similarity: 433/1104 - (39%)
• Gaps: 246/1104 - (22%)

  Fly    10 KRSLDLSEESTSESHAKRQCTENL--FWPEGEDDD---------SFFSNAHLEDLLDGRKEELFG 63
            :|.:....|...::...::..|.|  ...||.|.|         .|...:.::.||..|.:.::.
plant   280 QRKISQEYEQKIDAQECQELAEELLKILAEGNDRDVEIKLLEHLQFEKFSLVKFLLQNRLKVVWC 344

  Fly    64 TQATTSTNKMTQSG-SDDGLGLFADTSFPSAQSVPPNSASKPDEASAPTD-----KHQIDLADEE 122
            |:.....::..::. .::.|||.::.:....:.....:.:|..|.....|     :|.:|  |:.
plant   345 TRLARGRDQEERNQIEEEMLGLGSELAAIVKELHAKRATAKEREEKREKDIKEEAQHLMD--DDS 407

  Fly   123 NADKLFKKINLNDLSIAEMEDIFHGADDFSDPMV--QNTQLFLDAMTFKKPK-TPEKLLAPLKDD 184
            ..|        .|..:.:::|:     |..:..:  |...:.|:::.|.:.. |.|.....|.|.
plant   408 GVD--------GDRGMRDVDDL-----DLENGWLKGQRQVMDLESLAFNQGGFTRENNKCELPDR 459

  Fly   185 SMSFISKSVIEGLVQGTQYVTCEELKNQSLL---DPVNWETQAFADFEKNNQDIDKFPSKGEFYG 246
            |.....|...|..|   .:|:.:...|:.|:   |...|...||    :..|.:::..||  .||
plant   460 SFRIRGKEFDEVHV---PWVSKKFDSNEKLVKISDLPEWAQPAF----RGMQQLNRVQSK--VYG 515

  Fly   247 LPDKVKKMILEHKGINSLYEWQDECLNLPAIRQRKNLIYALPTSGGKTLVAEILMLRELLCR--- 308
                                        .|:.:..|::...||..|||.||.:.:|.:|...
plant   516 ----------------------------TALFKADNILLCAPTGAGKTNVAVLTILHQLGLNMNP 552

  Fly   309 -------ERNVLFILPYVSIVQEKVSAMSPFAIDLDFIVEEYTAGKGKCPPQPRRKRRSLFIASI 366
                   ...::::.|..::|.|.|.::|....|....|:|.:..:.....:  .|...:.:.:.
plant   553 GGTFNHGNYKIVYVAPMKALVAEVVDSLSQRLKDFGVTVKELSGDQSLTGQE--IKETQIIVTTP 615

  Fly   367 EKGAVLMDSLIDVQRPHEIGLVVVDELHLIGEKGRGATLEAF----LTKVMFLNANIQIVGMSAT 427
            ||..::.....|......:.|:::||:||: :..||..||:.    |.::.....:|::||:|||
plant   616 EKWDIITRKSGDRTYTQLVRLLIIDEIHLL-DDNRGPVLESIVARTLRQIESTKEHIRLVGLSAT 679

  Fly   428 IGNLSEISSFLNAD------VYTRGFRPVEL-KEYIKCGPDLLEINSAGQTLEEIFVPSRSVEYN 485
            :.|..:::|||..|      ::.|.:|||.| ::||  |.::.:.....|.:.:|.
plant   680 LPNCDDVASFLRVDLKNGLFIFDRSYRPVPLGQQYI--GINVKKPLRRFQLMNDIC--------- 733

  Fly   486 YSEAVKRADPDHLAGLISECAPEHCCLVFCPSRKNCENVALLLSRIVPKHKFFEHRRSEKLDLMD 550
            |.:.|.      :||       :|..|:|..|||.....|..:......:........|.....:
plant   734 YQKVVA------VAG-------KHQVLIFVHSRKETAKTARAIRDTAMANDTLSRFLKEDSQSRE 785

  Fly   551 ALDKMCGIL-SPVLAKTLPYGIAYHHSGLTTDERKYIETAYRFGVVTVICCTSTLAAGVNLPAKR 614
            .|..:.|:| :..|.:.||||.|.||:|||..:|:.:|..:|:|.:.|:..|:|||.||||||..
plant   786 ILKCLAGLLKNNDLKELLPYGFAIHHAGLTRTDREIVENQFRWGNLQVLISTATLAWGVNLPAHT 850

  Fly   615 VIIRAPYVGQ----EFLTL--CKYKQMVGRAGRAGLGEAGESILIAQSKDNLLVGQMLFSPMDKA 673
            |||:...|..    |::.|  ....||:|||||....:.||.|:|..           :|.:...
plant   851 VIIKGTQVYNPERGEWMELSPLDVMQMIGRAGRPQYDQQGEGIIITG-----------YSKLQYY 904

  Fly   674 LSSLDQNEAVGLQSLILSVVGLNLAECRRDLN-RLVNSTLLSVQAKSLEVAVNEIVLRILREMFK 737
            |..:  ||.:.::|..:|    .||:   .|| .:|..|:.:.:.....:....:.:|::|
plant   905 LRLM--NEQLPIESQFIS----KLAD---QLNAEIVLGTIQNAREACHWLGYTYLYVRMVR---- 956

  Fly   738 NKVLQLAEPQAKSKINSSDIITSQ---DVSQANRPAGDRRLLI---GQSTPFKLTNIGRAAFKAG 796
            |..|....|.|.:|    |::..:   |:..:.....|:..||   .:|..|::|::||.|....
plant   957 NPTLYGVSPDALAK----DLLLEERRADLIHSAATILDKNNLIKYDRKSGHFQVTDLGRIASYYY 1017

  Fly   797 IDYKRANAIHKELKQAQQQLILTNYLHL----LYLVVCFNSNERGDELF---------------- 841
            |.:....|.::.||.....:.|.....|    .|:.|      |.||..
plant  1018 ISHGTIAAYNENLKPTMNDIELCRLFSLSEEFKYVTV------RQDEKMELAKLLDRVPIPVKET 1076

  Fly   842 ----PADASILFGVYTS-LPLDSQAMFKQLGFTEAHAARLFKTQSVQGPLSLQLNRLYKVLILAD 901
                .|..::|..||.| |.|:..::...:.:....|.||             |..::::::
plant  1077 LEDPSAKINVLLQVYISKLKLEGLSLTSDMVYITQSAGRL-------------LRAIFEIVL--- 1125

  Fly   902 ILNLLPIPSVASKYNVERGTLQHLISQSTAAASAIV--RLCEELEEFWCYKPLFERILHKMDR-- 962
                            :||..|  :||.....|.:|  |:.......|.:..:.:.||.|:::
plant  1126 ----------------KRGWAQ--LSQKALNLSKMVGKRMWSVQTPLWQFPGIPKEILMKLEKND 1172

  Fly   963 --------CGTFELEPLMELPAVKINRARQLYAAGFQTIGDIARVRPSHLVQSLEHMPLRVATE 1018
                    ..:.||..|:..|  |:.|....|...|..:...|.|:|  :.:|:..:.|.|..:
plant  1173 LVWERYYDLSSQELGELICNP--KMGRPLHKYIHQFPKLKLAAHVQP--ISRSVLQVELTVTPD 1232

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mus301	NP_648178.1	DEXHc_POLQ-like	247..449	CDD:350784	45/221 (20%)
		BRR2	255..828	CDD:440817	149/611 (24%)
AT2G42270	NP_181756.1	Helicase_PWI	265..377	CDD:436309	16/96 (17%)
		BRR2	488..1019	CDD:440817	151/619 (24%)
		DEXHc_Brr2_1	489..702	CDD:350777	53/249 (21%)
		Sec63	1007..1310	CDD:460740	52/270 (19%)
		BRR2	1349..1877	CDD:440817
		DEXHc_Brr2_2	1349..1540	CDD:350779
		SEC63	1837..2160	CDD:214744