Protein Alignment mus301 and polq

DIOPT Version :9

• Sequence 1: NP_648178.1
• Gene: mus301 / 38905
• FlyBaseID: FBgn0002899
• Length: 1051
• Species: Drosophila melanogaster
• Sequence 2: XP_021329106.1
• Gene: polq / 566079
• ZFINID: ZDB-GENE-040724-232
• Length: 2579
• Species: Danio rerio
• Alignment Length: 1172
• Identity: 305/1172 - (26%)
• Similarity: 514/1172 - (43%)
• Gaps: 241/1172 - (20%)

  Fly     4 KHNLCKKRSLDLSEESTSESHAKRQCTENLF---------------WPEGEDDDSFFSNAHLEDL 53
            :|.:.|.|.|.|::|...:......|.|::.               |..|  |.|...:..:...
Zfish    13 QHRIVKTRGLSLADEKPGQRQLSNLCQEDVSENRSCIAPKQIQSKQWMPG--DSSLAMDEEILQA 75

  Fly    54 LDGRKEELFGTQATTSTNKMTQSGSDDGLGLFADTSFPSAQSVPPNSASKPDEASAPTDKHQIDL 118
            :|....|:.      ...|:.:....:...|..:..||....:.....::....|:|::..:...
Zfish    76 IDELGPEVL------KFKKIEKIQQTEPAPLKKNCDFPKIPEIQKEQNTENISPSSPSEHKRTRT 134

  Fly   119 ADEENAD--KLFKKINLNDLSIAEMEDIFHGAD---DFSDPMVQNTQLFLDAM--TFKKPKTPEK 176
            ..::..|  .|.:|:..::....|:....|...   |:|.|     |..|::|  |.|..|:.:|
Zfish   135 QAKKEGDWKDLAQKLLFSETKKIEVGGRTHDLKQNRDYSSP-----QKILNSMKKTSKVAKSKQK 194

  Fly   177 L-----LAPLKDDSMSFISKSVIEGLVQGTQYVTCEE----------LKNQS---LLDPVNWETQ 223
            |     .:|  :||..:|       |...|.....:|          |||||   |..|...:..
Zfish   195 LNFREVTSP--NDSKDYI-------LFSPTHMAAAKERSVLQQQKRSLKNQSVSVLTPPPGLDLT 250

  Fly   224 AFADFEKNN-----------QDIDKFPSKGEFYGLPDKVKKMILE---HKGINSLYEWQDECLNL 274
            ...|...::           ..:||.....  :|||    |.:||   ..|::.::|||.|||.|
Zfish   251 VLGDATLSDAAQSIHMGRPADQLDKLLLSS--WGLP----KPVLEKYQSLGVHRMFEWQAECLTL 309

  Fly   275 PAIRQRKNLIYALPTSGGKTLVAEILMLRELLCRERNVLFILPYVSIVQEKVSAMSPFAIDLDFI 339
            ..:.:.:||:|:.|||.|||||:|:|:|:.:|...:..:||||:||:.:||:..:.....:....
Zfish   310 GKVLEGQNLVYSAPTSAGKTLVSELLILKRVLETRQKAMFILPFVSVAREKMFYLQNVFQEAGIR 374

  Fly   340 VEEY---TAGKGKCPPQPRRKRRSLFIASIEKGAVLMDSLIDVQRPHEIGLVVVDELHLIGEKGR 401
            ||.|   |:..|..      ....:.:.:|||...|::.||:..:...:|.|||||||::|:.||
Zfish   375 VEGYMGSTSAAGGF------SALDVAVCTIEKANGLVNRLIEEDKLDLLGTVVVDELHMVGDSGR 433

  Fly   402 GATLEAFLTKVMFL-------------NANIQIVGMSATIGNLSEISSFLNADVYTRGFRPVELK 453
            |..||..|||:.::             :..:||:|||||:.||..::.:|:|::|:..:|||.|.
Zfish   434 GYLLELLLTKIRYIAQKTATRNSGQSTSTGVQIIGMSATLPNLDLLARWLSAELYSTNYRPVPLM 498

  Fly   454 EYIKCGPDLLE--INSAGQTLEEIFVPSRSVEYNYSEAVKRADPDHLAGLISECAPE-HCCLVFC 515
            |::|.|.::.:  :|...|     |.|:..:         :.|.||:..|..|...: |..|:||
Zfish   499 EWVKIGTNIYDGSLNLVRQ-----FTPALPI---------KGDDDHIVSLCFETVQDGHSALLFC 549

  Fly   516 PSRKNCENVALLLSRIVPKHKFF--EHRRSEK--------------LDLMDALDKMCGILSPVLA 564
            ||:..||.:|..:.|     :|:  .|:..:.              ||::..|.:....|..||.
Zfish   550 PSKNWCEKLADSIGR-----EFYNLHHKEMQSGSGGQSIFLNQEGLLDVLAQLKRTPAGLDHVLQ 609

  Fly   565 KTLPYGIAYHHSGLTTDERKYIETAYRFGVVTVICCTSTLAAGVNLPAKRVIIRAPYVGQEFLTL 629
            :|:|:|:|:||:|||.|||..:|.|:|.|.:.|:..||||::||||||:|||||.|......|.:
Zfish   610 RTVPWGVAFHHAGLTFDERDILEGAFRQGYIRVLAATSTLSSGVNLPARRVIIRTPVFNGHLLDI 674

  Fly   630 CKYKQMVGRAGRAGLGEAGESILIAQSKDNLLVGQMLFSPMDKALSS-LDQNEAVG-----LQSL 688
            ..||||||||||.|:...|||:|:.:..:. ..|..|.....|.:|| |.:.|..|     |:::
Zfish   675 LTYKQMVGRAGRKGVDTIGESVLVCKEAER-AKGMSLIQGSLKPISSCLVKREGEGVTTSMLRAI 738

  Fly   689 ILSVVGLNLAECRRDLNRLVNSTLLSVQAKSLEVAVNEIVLRILREMFKNKVLQLAEPQAKSK-- 751
            :..:|| .:|...:|:......|||:....:.|...:.                 :|.:|::|
Zfish   739 LEIIVG-GVASSPQDVRMYAACTLLAASIAAEEAHQDG-----------------SESEARNKGA 785

  Fly   752 -------INSSDIITSQDVSQANRPAGDRRLLIGQSTPFKLTNIGRAAFKAGIDYKRANAIHKEL 809
                   :..::.|..|......|              :..|::|.|...:.:....|..|..:|
Zfish   786 IEACIEWLMDNEFIHIQKEGDVER--------------YCPTHLGSATLSSSLSPPEALGIFADL 836

  Fly   810 KQAQQQLILTNYLHLLYLVVCFNSNERGDELFPA-------DASILFGVYTSLPLDSQAMFKQLG 867
            ::|.:..:|.|.||:||            ::.|.       |....|.::..||...:.:.:.:|
Zfish   837 QRAMKGFVLENDLHILY------------QITPVYVDWTTIDWYQFFCLWEQLPSAMKRVAEMVG 889

  Fly   868 FTEAHAAR------LFKTQSVQGPLSLQLNRLYKVLILADILNLLPIPSVASKYNVERGTLQHLI 926
            ..|...||      :.||:..:..:::. .|.:..|:|.|:::..|:.:||.||...||.||.|.
Zfish   890 IQEGFLARSVGGKLIAKTEKQRRQMAIH-KRFFTTLVLLDLVSEEPLGAVAKKYGCSRGQLQSLQ 953

  Fly   927 SQSTAAASAIVRLCEELEEFWCYKPLF-----ERILHKMDRCGTFELEPLMELPAVKINRARQLY 986
            ..::..|..:...|..|.  |....|.     .|:...:.|    ||..|:.:..:...|||.||
Zfish   954 QSASTYAGMVTVFCNRLG--WHNLELLLSQFQSRLSFGVQR----ELCDLVRISLLTAQRARTLY 1012

  Fly   987 AAGFQTIGDIARVRPSHLVQSL-EHMPLRVATEIVSAAKIILMKKLDHLEEETENLKD--CLKTS 1048
            ::||.|:.::||...|.:.::| :.:|.:.:.:.|           |..|.|.:..|.  |:..|
Zfish  1013 SSGFVTVAELARADVSEVEKALRKAIPFKSSRQAV-----------DESEVEAQERKSMRCIWVS 1066

  Fly  1049 DK 1050
            .|
Zfish  1067 GK 1068

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mus301	NP_648178.1	BRR2	247..998	CDD:224125	238/821 (29%)
		DEXHc_POLQ-like	247..449	CDD:350784	76/220 (35%)
polq	XP_021329106.1	BRR2	264..1038	CDD:333051	245/856 (29%)
		DNA_pol_A_theta	2096..2574	CDD:176475

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0749
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D103838at33208
OrthoFinder	1	1.000	-	-		FOG0001214
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101025
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.720