Protein Alignment mus301 and ascc3

DIOPT Version :10

• Sequence 1: NP_648178.1
• Gene: mus301 / 38905
• FlyBaseID: FBgn0002899
• Length: 1051
• Species: Drosophila melanogaster
• Sequence 2: NP_001361664.2
• Gene: ascc3 / 448036
• XenbaseID: XB-GENE-6095530
• Length: 2206
• Species: Xenopus tropicalis
• Alignment Length: 1098
• Identity: 227/1098 - (20%)
• Similarity: 398/1098 - (36%)
• Gaps: 312/1098 - (28%)

  Fly     9 KKRSLDL---------SEESTSESHAKRQCTENLFWPEGEDDDSFF----------------SNA 48
            |..|||.         :.:.||...|:...|.     |.|||.||.                ...
 Frog   192 KDISLDFRKFHSDHIETPDGTSGGQARHNRTY-----ETEDDSSFLYDEVKKYVMHNLQSSSGGP 251

  Fly    49 HLEDLLDGRKEELFGTQATTSTNKMTQSGSDDGLG----LFADTSFPSAQSVPPNSASKPD---- 105
            .:.||.    ..||...|:|.:|...|:...:.||    .|.:......|.:...|.:..:
 Frog   252 TVNDLC----STLFEMLASTKSNDELQNELFELLGPEGLTFIEMLLQQRQKIVERSLNYDNKMYT 312

  Fly   106 ----------EASAPTDKHQIDLADEENADKLFKKINLNDLSIAEMEDIFHGADDFS-------D 153
                      |.:.|....|:.:..|:. .:|.|:....:...|:.|.......|.|       |
 Frog   313 SQEQRMRNYGENTKPNYGCQVTVQSEQE-KQLMKQYRREEKRNAKREKRLGDDGDISGEGLVGFD 376

  Fly   154 P---MVQNTQLFLDAMTF----KKPKTPEKLLAPLKDDSMSFISKSVIEGLVQGTQYVTCEELKN 211
            |   .:|......:|.|.    |:....|::..|...||.:...|:  ...:.|.:.:..|.::.
 Frog   377 PRELRMQREHALSNARTMPILGKERDYWERIKYPHVYDSHAEAMKT--SAFIGGAKLLLPEGIQR 439

  Fly   212 QSLLDPVNWETQAFADFEKNNQDIDK------------FPSKGEFYGLPDKVKKMILEHKGINSL 264
            :                  ||:..::            |..|..:....|:|.:::.  ||:..|
 Frog   440 E------------------NNKIFEEVKIPVSEPMPIGFEEKPVYIKDLDEVGQLVF--KGVKRL 484

  Fly   265 YEWQDECLNLPAIRQRKNLIYALPTSGGKTLVAEILMLRELLCRERN------------VLFILP 317
            ...|..... .|....:|::...||..|||.:|.:.:|.|:   .:|            ::::.|
 Frog   485 NRIQSIVFE-TAYNTNENMLICAPTGAGKTNIAMLTVLHEI---HQNIEQGVIKKDAFKIVYVAP 545

  Fly   318 YVSIVQEKVSAMS----PFAIDLDFIVEEYTAGKGKCPPQPRRKRRSLFIASIEK-GAVLMDSLI 377
            ..::..|..:..|    |..|.:..:..:....||:.      .|..:.:.:.|| ..|...|:.
 Frog   546 MKALAAEMTNYFSKRLEPLGISVKELTGDMQLSKGEI------LRTQMLVTTPEKWDVVTRKSVG 604

  Fly   378 DVQRPHEIGLVVVDELHLIGEKGRGATLEAF----LTKVMFLNANIQIVGMSATIGNLSEISSFL 438
            ||.....:.|:::||:||:.| .||..||:.    |.:|....:.|:|:|:|||:.|..:::|||
 Frog   605 DVALSQLVRLLILDEVHLLHE-DRGPVLESLVARTLRQVESTQSMIRILGLSATLPNYLDVASFL 668

  Fly   439 NAD------VYTRGFRPVELKEYIKCGPDLLEINSAGQT-----LEEIFVPSRSVEYNYSEAVKR 492
            :.:      .:...||||.|      |...:.|.|..:|     :||:.         |...:|
 Frog   669 HVNPFIGLFFFDGRFRPVPL------GQTFIGIKSTNKTQQLHDVEEVC---------YENVLK- 717

  Fly   493 ADPDHLAGLISECAPEHCCLVFCPSRKNCENVALLLSRIVPKHK---FF------EHRRSEKLDL 548
                       |.......:||..:|.:....|:.|..:...:.   :|      |:.::|| .:
 Frog   718 -----------EIKAGRQVMVFVHARNSTVRTAMALRELAKNNGHICYFLPNQGPEYGQAEK-QV 770

  Fly   549 MDALDKMCGILSPVLAKTLPYGIAYHHSGLTTDERKYIETAYRFGVVTVICCTSTLAAGVNLPAK 613
            ..:.:|.       |.:..|.|.:.||:|:...:|..:|..:..|.:.|:.||:|||.||||||.
 Frog   771 QRSRNKQ-------LRELFPDGFSIHHAGMLRQDRSLVENLFSQGHIKVLVCTATLAWGVNLPAH 828

  Fly   614 RVII---------RAPYVGQEFLTLCKYKQMVGRAGRAGLGEAGESILIAQ-----------SKD 658
            .|||         |..:|.   |.:....|:.|||||....:.||..:|..           ::.
 Frog   829 AVIIKGTQIYDAKRGSFVD---LGILDVMQIFGRAGRPQFDKFGEGTIITTHDKLSHYLTLLTQQ 890

  Fly   659 NLLVGQMLFSPMDKALSSLDQNEAVGLQSLILSVVGLNLAECRRDLNRLVNSTLLSVQAKSLEVA 723
            |.:..|.|.|..|    :|:...|:|..:.:...|            :.::.|.|.|:.::
 Frog   891 NPIESQFLESLAD----NLNAEVALGTVTNVEEAV------------KWLSYTYLYVRMRA---- 935

  Fly   724 VNEIVLRILREMFKNKVLQLAEPQAKSKINSSDIITSQDVSQANRPAGDRRLLIGQSTP--FKLT 786
             |.:|..|     .:||.|:.....|.:        .|.|.:|.|.....|::..:...  |..|
 Frog   936 -NPLVYGI-----SHKVYQMDPALEKHR--------EQLVIEAGRKLDKARMIRFEERTGFFSST 986

  Fly   787 NIGRAAFKAGIDYKRANAI------HK----------------ELKQAQQQL-----ILTNY--L 822
            ::||.:....|.|......      ||                ::|...:::     ::.||  |
 Frog   987 DLGRTSSHFYIKYNTIETFNELFDAHKTEGDIVAIVSKAEEFEQIKVRDEEIEELEHLIHNYCEL 1051

  Fly   823 HLLYLVVCFNSNERGDELFPADASILFGVYTSL-PLDSQAMFKQLGFTEAHAARLFKTQSVQGPL 886
            |:          ..|.|......:||...|... .:|:.::.....:...:|||:     |:...
 Frog  1052 HV----------AGGVENSYGKINILLQTYIGRGEIDNFSLISDSAYVAQNAARI-----VRALF 1101

  Fly   887 SLQLNR-----LYKVLILADIL--------------NLLPIPSVASKYNVERGTLQHL 925
            .:.|.:     .|::|.|:.::              ::|| |||.||...::.|:..|
 Frog  1102 EIALRKRWPAMTYRLLNLSKVIDKRLWGWASPLRQFSVLP-PSVLSKLEEKKLTIDKL 1158

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mus301	NP_648178.1	DEXHc_POLQ-like	247..449	CDD:350784	54/228 (24%)
		BRR2	255..828	CDD:440817	148/664 (22%)
ascc3	NP_001361664.2	None