Protein Alignment mus301 and PolQ

DIOPT Version :10

• Sequence 1: NP_648178.1
• Gene: mus301 / 38905
• FlyBaseID: FBgn0002899
• Length: 1051
• Species: Drosophila melanogaster
• Sequence 2: NP_524333.1
• Gene: PolQ / 41571
• FlyBaseID: FBgn0002905
• Length: 2059
• Species: Drosophila melanogaster
• Alignment Length: 983
• Identity: 273/983 - (27%)
• Similarity: 453/983 - (46%)
• Gaps: 165/983 - (16%)

  Fly    99 NSASKPDEAS----APTDKHQIDLADEENADKLFKKINLNDLSIAEMEDIFHGADDFSDPMVQNT 159
            |.|.||.|.|    :...:|...::::::.|: .:...|||....:..  |.|.|..:|.::.
  Fly    66 NQAHKPAEQSVVNVSQVQQHMAVVSNQDSEDQ-SRSSALNDQICTQSS--FEGEDAGADAVLD-- 125

  Fly   160 QLFLDAMTFKKPKTPEKLLAPLKDDSMSFISKSVIEGLVQGTQYVTCEELKNQSLLDPVNWETQA 224
            |..||..:|..|...|:....||:|.:.  |.||               |..|.....::..||.
  Fly   126 QPNLDENSFLCPAQDEEASEQLKEDILH--SHSV---------------LAKQEFYQEISQVTQN 173

  Fly   225 FADFEKNNQDI--------DKFPSKGEF------------YGLPDKVKKMILEHKGINSLYEWQD 269
            .:....|...:        :..|.:...            :.||..::.. .:.||:..:::||.
  Fly   174 LSSMSPNQLRVSPNSSRIREAMPERPAMPLDLNTLRSISAWNLPMSIQAE-YKKKGVVDMFDWQV 237

  Fly   270 ECLNLPAIR-QRKNLIYALPTSGGKTLVAEILMLRELLCRERNVLFILPYVSIVQEKVSAMSPFA 333
            |||:.|.:. :..||:|:.|||.|||||:|||||:.:|.|.:.||.|||::|:|:||:..|....
  Fly   238 ECLSKPRLLFEHCNLVYSAPTSAGKTLVSEILMLKTVLERGKKVLLILPFISVVREKMFYMQDLL 302

  Fly   334 IDLDFIVEEYTAGKGKCPPQPRRKRRSLFIA--SIEKGAVLMDSLIDVQRPHEIGLVVVDELHLI 396
            ....:.||.:..|.     .|.....||.:|  :|||...:::.|::..:...||:|||||:|||
  Fly   303 TPAGYRVEGFYGGY-----TPPGGFESLHVAICTIEKANSIVNKLMEQGKLETIGMVVVDEVHLI 362

  Fly   397 GEKGRGATLEAFLTKVMFLN----ANIQIVGMSATIGNLSEISSFLNADVYTRGFRPVELKEYIK 457
            .:||||..||..|.|:::::    ..||::.||||:.|:..:.|:|:|::|...:|||.|||.||
  Fly   363 SDKGRGYILELLLAKILYMSRRNGLQIQVITMSATLENVQLLQSWLDAELYITNYRPVALKEMIK 427

  Fly   458 CGPDLLEINSAGQTLEEIFVPSRSVEYNYSEAVKR-------------ADPDHLAGLISECAPEH 509
            .|                     :|.|::...:.|             .|.|.:|.|..|...|.
  Fly   428 VG---------------------TVIYDHRLKLVRDVAKQKVLLKGLENDSDDVALLCIETLLEG 471

  Fly   510 C-CLVFCPSRKNCENVALLLSRIVPKHKFFEHRRSEKL-----------------DLMDALDKMC 556
            | .:|||||:..|||:|:.|:..:......|....::|                 |:...||
  Fly   472 CSVIVFCPSKDWCENLAVQLATAIHVQIKSETVLGQRLRTNLNPRAIAEVKQQLRDIPTGLD--- 533

  Fly   557 GILSPVLAKTLPYGIAYHHSGLTTDERKYIETAYRFGVVTVICCTSTLAAGVNLPAKRVIIRAPY 621
            |::|    |.:.|..|:||:||||:||..||.:::.|.:.|:..||||::||||||:||:||:|.
  Fly   534 GVMS----KAITYACAFHHAGLTTEERDIIEASFKAGALKVLVATSTLSSGVNLPARRVLIRSPL 594

  Fly   622 VGQEFLTLCKYKQMVGRAGRAGLGEAGESILIAQSKDNLLVGQMLFSPMDKALSSLDQNEAVGLQ 686
            .|.:.::...|:||:|||||.|....||||||....:..:...::.|.:....|.||.:.:..|:
  Fly   595 FGGKQMSSLTYRQMIGRAGRMGKDTLGESILICNEINARMGRDLVVSELQPITSCLDMDGSTHLK 659

  Fly   687 SLILSVVGLNLAECRRDLNRLVNSTLLSVQAKSLEVAVNEIVLRILREMFKNKVLQLAEPQAKSK 751
            ..:|.|:...:|..:.|::..||.||||.|                 :.|..|.....|....:.
  Fly   660 RALLEVISSGVANTKEDIDFFVNCTLLSAQ-----------------KAFHAKEKPPDEESDANY 707

  Fly   752 INSS-DIITSQDVSQANRPAGDRRLLIGQSTPFKLTNIGRAAFKAGIDYKRANAIHKELKQAQQQ 815
            ||.: |.:...:..:..|  .:.|    ::..:..|.:|.|...:.:.......:..||:::::.
  Fly   708 INDALDFLVEYEFVRLQR--NEER----ETAVYVATRLGAACLASSMPPTDGLILFAELQKSRRS 766

  Fly   816 LILTNYLHLLYLV----VCFNSNERGDELFPADASILFGVYTSLPLDSQAMFKQLGFTEAHAARL 876
            .:|.:.||.:|||    ||:       :|...|..:...::..|....:.:.:.:|..:|...:.
  Fly   767 FVLESELHAVYLVTPYSVCY-------QLQDIDWLLYVHMWEKLSSPMKKVGELVGVRDAFLYKA 824

  Fly   877 FKTQSVQGPLSLQLN-RLYKVLILADILNLLPIPSVASKYNVERGTLQHLISQSTAAASAIVRLC 940
            .:.|:......:|:: |.|..|.|.:::|..||..|..||...||.||.|...::..|..:...|
  Fly   825 LRGQTKLDYKQMQIHKRFYIALALEELVNETPINVVVHKYKCHRGMLQSLQQMASTFAGIVTAFC 889

  Fly   941 EELEEFWCYKPLF-----ERILHKMDRCGTFELEPLMELPAVKINRARQLYAAGFQTIGDIARVR 1000
            ..|:  |....|.     :|:...:.|    :|..||.:|.:...|||.|:.||..::.::|...
  Fly   890 NSLQ--WSTLALIVSQFKDRLFFGIHR----DLIDLMRIPDLSQKRARALFDAGITSLVELAGAD 948

  Fly  1001 PSHLVQSL 1008
            |..|.:.|
  Fly   949 PVELEKVL 956

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mus301	NP_648178.1	DEXHc_POLQ-like	247..449	CDD:350784	78/208 (38%)
		BRR2	255..828	CDD:440817	191/611 (31%)
PolQ	NP_524333.1	BRR2	216..779	CDD:440817	193/619 (31%)
		DNA_pol_A_theta	1668..2053	CDD:176475