Protein Alignment mus301 and Snrnp200

DIOPT Version :10

• Sequence 1: NP_648178.1
• Gene: mus301 / 38905
• FlyBaseID: FBgn0002899
• Length: 1051
• Species: Drosophila melanogaster
• Sequence 2: NP_001032855.2
• Gene: Snrnp200 / 296126
• RGDID: 1561120
• Length: 2136
• Species: Rattus norvegicus
• Alignment Length: 1011
• Identity: 229/1011 - (22%)
• Similarity: 379/1011 - (37%)
• Gaps: 268/1011 - (26%)

  Fly   107 ASAPTDKHQIDLADEENADKLFKKINLNDLSIAEMEDIFHGADDFSDPMVQNTQLFLDAMTFKKP 171
            |||.::..:..:..:..||....|. |..|...|.||:.. .:......|:.:::..|..|....
  Rat   335 ASAQSEAEKERIMGKMEADPELSKF-LYQLHETEKEDLIR-EERSRRERVRQSRMDTDLETMDLD 397

  Fly   172 KTPEKLLAPLKDDSMSFISKSV--IEGLV--QGTQYVTCEELKNQSLLDPVNWETQAFADFEKNN 232
            :..| .|||          :.|  :|.||  ||:.::.   .|...|.|      .:|....|..
  Rat   398 QGGE-ALAP----------RQVLDLEDLVFTQGSHFMA---NKRCQLPD------GSFRRQRKGY 442

  Fly   233 QDIDKFPSKGEFYG-----LP-DKVKKMI-LEHKGINSLYEWQDECLNLPAIRQRKNLIYALPTS 290
            :::.....|.:.:|     || :|:.|.. ...:|..:|...|.: |...|:...:||:...||.
  Rat   443 EEVHVPALKPKPFGSEEQLLPVEKLPKYAQAGFEGFKTLNRIQSK-LYRAALETDENLLLCAPTG 506

  Fly   291 GGKTLVAEILMLRE----------LLCRERNVLFILPYVSIVQEKVSAMSPFAIDLDFIVEEYTA 345
            .|||.||.:.||||          :...:..:::|.|..|:|||.|.:...........|.|.|.
  Rat   507 AGKTNVALMCMLREIGKHINMDGTINVDDFKIIYIAPMRSLVQEMVGSFGKRLATYGITVAELTG 571

  Fly   346 GKGKCPPQPRRKRRSLFIASIEKGAVLMDSLIDVQRPHEIGLVVVDELHLIGEKGRGATLEAFLT 410
            ....|  :.......:.:.:.||..::.....:......:.|:|:||:||:.: .||..|||.:.
  Rat   572 DHQLC--KEEISATQIIVCTPEKWDIITRKGGERTYTQLVRLIVLDEIHLLHD-DRGPVLEALVA 633

  Fly   411 K----VMFLNANIQIVGMSATIGNLSEISSFLNAD------VYTRGFRPVELKEYIKCGPDLLEI 465
            :    :.....:::::|:|||:.|..::::||..|      .:...||||.|:
  Rat   634 RAIRNIEMTQEDVRLIGLSATLPNYEDVATFLRVDPAKGLFYFDNSFRPVPLE------------ 686

  Fly   466 NSAGQTLEEIFVPSRSVEYNYSEAVKRADPDHLAGLISECAPEHC----CLVFCPSRKNCENVAL 526
                ||.         |.....:|:||.  ..:..::.|...||.    .|||..|||.....|.
  Rat   687 ----QTY---------VGITEKKAIKRF--QIMNEIVYEKIMEHAGKNQVLVFVHSRKETGKTAR 736

  Fly   527 LLSRIVPKHK---FFEHRRSEKLDLMDALDKMCGILSPVLAKTLPYGIAYHHSGLTTDERKYIET 588
            .:..:..:..   .|....|...:::....:.|..|.  |...||||.|.||:|:|..:|..:|.
  Rat   737 AIRDMCLEKDTLGLFLREGSASTEVLRTEAEQCKNLE--LKDLLPYGFAIHHAGMTRVDRTLVED 799

  Fly   589 AYRFGVVTVICCTSTLAAGVNLPAKRVIIR-----APYVGQ-EFLTLCKYKQMVGRAGRAGLGEA 647
            .:....:.|:..|:|||.||||||..|||:     :|..|: ..|......||:|||||......
  Rat   800 LFADKHIQVLVSTATLAWGVNLPAHTVIIKGTQVYSPEKGRWTELGALDILQMLGRAGRPQYDTK 864

  Fly   648 GESILIAQSKDNLLVGQMLFSPMDKALSSLDQNEAVGLQSLILSVVGLNLAECRRDLNRLVNSTL 712
            ||.|||...      |::.:     .||.|  |:.:.::|.::|           .|..::|:.:
  Rat   865 GEGILITSH------GELQY-----YLSLL--NQQLPIESQMVS-----------KLPDMLNAEI 905

  Fly   713 LSVQAKSLEVAVN-----EIVLRILRE---------------MFKNKVLQLAEPQAKSKINSSDI 757
            :....::.:.|||     .:.:|:||.               :...:.|.|....|.       :
  Rat   906 VLGNVQNAKDAVNWLGYAYLYIRMLRSPTLYGISHDDLKGDPLLDQRRLDLVHTAAL-------M 963

  Fly   758 ITSQDVSQANRPAGDRRLLIGQSTPFKLTNIGRAAFKAGIDYKRANAIHKELKQAQQQLILTNYL 822
            :...::.:.::..|:          |::|.:||.|    ..|...|    :..|...||
  Rat   964 LDKNNLVKYDKKTGN----------FQVTELGRIA----SHYYITN----DTVQTYNQL------ 1004

  Fly   823 HLLYLVVCFNSNERGDELFPADASI-LFGVYTSLPLDSQAMFKQLGFTEAHAARLFKTQSVQGPL 886
                             |.|..:.| ||.|::   |.|:                ||..:|:...
  Rat  1005 -----------------LKPTLSEIELFRVFS---LSSE----------------FKNITVREEE 1033

  Fly   887 SLQLNRLYKVLILADILNLLPIP------SVASKYNVERGTLQHLISQ--------------STA 931
            .|:|.:|         |..:|||      ..::|.||   .||..|||              .|.
  Rat  1034 KLELQKL---------LERVPIPVKESIEEPSAKINV---LLQAFISQLKLEGFALMADMVYVTQ 1086

  Fly   932 AASAIVRLCEE--LEEFWCY---------KPLFERILHKMDRCGTFELEPLMELPAVKINRA--- 982
            :|..::|...|  |...|..         |.:.:|:...|  |...:...|.|....||.:.
  Rat  1087 SAGRLMRAIFEIVLNRGWAQLTDKTLNLCKMIDKRMWQSM--CPLRQFRKLPEEVVKKIEKKNFP 1149

  Fly   983 -RQLYAAGFQTIGDIARV--------RPSHLVQSLE 1009
             .:||......||::.|:        :..||...||
  Rat  1150 FERLYDLNHNEIGELIRMPKMGKTIHKYVHLFPKLE 1185

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mus301	NP_648178.1	DEXHc_POLQ-like	247..449	CDD:350784	55/223 (25%)
		BRR2	255..828	CDD:440817	145/626 (23%)
Snrnp200	NP_001032855.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	39..80
		Helicase_PWI	254..363	CDD:436309	7/28 (25%)
		BRR2	462..1017	CDD:440817	154/659 (23%)
		DEXHc_Brr2_1	464..677	CDD:350777	52/216 (24%)
		DEAH box	615..618		2/2 (100%)
		Sec63	982..1285	CDD:460740	58/268 (22%)
		Interaction with TSSC4. /evidence=ECO:0000250|UniProtKB:O75643	1282..2136
		BRR2	1309..1849	CDD:440817
		DEXHc_Brr2_2	1325..1515	CDD:350779
		DEAH box	1454..1457
		SEC63	1809..2125	CDD:214744