Protein Alignment mus301 and Polq

DIOPT Version :10

• Sequence 1: NP_648178.1
• Gene: mus301 / 38905
• FlyBaseID: FBgn0002899
• Length: 1051
• Species: Drosophila melanogaster
• Sequence 2: NP_001099348.1
• Gene: Polq / 288079
• RGDID: 1309795
• Length: 2547
• Species: Rattus norvegicus
• Alignment Length: 976
• Identity: 287/976 - (29%)
• Similarity: 441/976 - (45%)
• Gaps: 221/976 - (22%)

  Fly   147 GADDFS-----DPMVQNTQLFLDAMTFKKPKTPEKLLAPLKDDSMSFISKSVIEGLVQGTQYV-- 204
            |:|.||     |..|                :|:.|..|:         .|...||.:|.:..
  Rat    16 GSDSFSFSGDGDSCV----------------SPQLLCRPV---------LSPPPGLGRGRRLAGT 55

  Fly   205 -TCEELKNQSLLDPV---NWETQAFADFEKNNQDIDKFPSKGEFYGLPDKVKKMILE--HK-GIN 262
             ||::..:...:|.:   ||                         |||    |.:||  |. |:.
  Rat    56 GTCKQRVSDDQIDQLLLANW-------------------------GLP----KAVLEKYHNFGVK 91

  Fly   263 SLYEWQDECLNLPAIRQRKNLIYALPTSGGKTLVAEILMLRELLCRERNVLFILPYVSIVQEKVS 327
            .::|||.|||.|..:.:.|||:|:.|||.|||||||:|:|:.:|...:..|||||:||:.:||..
  Rat    92 KMFEWQAECLLLGQVLEGKNLVYSAPTSAGKTLVAELLILKRVLETRKKALFILPFVSVAKEKKY 156

  Fly   328 AMSPFAIDLDFIVEEYTAGKGKCPPQPRRKRRSLFIASIEKGAVLMDSLIDVQRPHEIGLVVVDE 392
            .:.....::...|:.|   .|...|..|.....:.:.:||:...|::.||:..:...:|.|||||
  Rat   157 YLQSLFQEVGIKVDGY---MGSTSPTGRFSSLDVAVCTIERANGLINRLIEENKMDLLGTVVVDE 218

  Fly   393 LHLIGEKGRGATLEAFLTKVMF---------------LNANIQIVGMSATIGNLSEISSFLNADV 442
            ||::|:..||..||..||||.|               |...:||||||||:.||..::|:|||::
  Rat   219 LHMLGDSHRGYLLELLLTKVCFVTRKSASCQADSASALACAVQIVGMSATLPNLQLVASWLNAEL 283

  Fly   443 YTRGFRPVELKEYIKCGPDLLEINSAGQTLEEIFVPSRSVEYNYSEAVKRADPDHLAGLISECAP 507
            |...||||.|.|.||.|..:.:   :...|...|.|...|         :.|.||:..|..|...
  Rat   284 YHTDFRPVPLLESIKVGNSIYD---SSMKLVREFQPLLQV---------KGDEDHIVSLCYETVR 336

  Fly   508 E-HCCLVFCPSRKNCENVALLLSRIVPKHKFFE-HRRSE-----------------KLDLMDALD 553
            : |..||||||:|.||.||.:::|     :|:. |.:.|                 .|:::|.|.
  Rat   337 DNHSVLVFCPSKKWCEKVADIIAR-----EFYNLHHQPEGLVKSSEFPPVILDQKSLLEVIDQLK 396

  Fly   554 KMCGILSPVLAKTLPYGIAYHHSGLTTDERKYIETAYRFGVVTVICCTSTLAAGVNLPAKRVIIR 618
            :....|..||..|:|:|:|:||:|||.:||..||.|:|.|::.|:..||||::||||||:|||||
  Rat   397 RSPSGLDSVLKNTVPWGVAFHHAGLTFEERDIIEGAFRQGLIRVLAATSTLSSGVNLPARRVIIR 461

  Fly   619 APYVGQEFLTLCKYKQMVGRAGRAGLGEAGESILIAQSKDN-----LLVGQMLFSPMDKALSSLD 678
            .|..|.:.|.:..||||||||||.|:...|||||:.::.:.     ||.|.:  .|:...|.|..
  Rat   462 TPVFGGQPLDILTYKQMVGRAGRKGVDTMGESILVCKNSEKSKGIALLQGSL--EPVHSCLQSQG 524

  Fly   679 QNEAVGLQSLILSVVGLNLAECRRDLNRLVNSTLLSVQAKS------------LEVAVNEIVLRI 731
            :..:..::: ||.::...:|...:|:......|.|:...|.            ...||:..|..:
  Rat   525 EVTSTMIRA-ILEIIVSGVASTSQDMQTYAACTFLAADVKEGKQGIQRNRDDVQRGAVDACVTWL 588

  Fly   732 LREMFKNKVLQLAEPQAKSKINSSDIITSQDVSQANRPAGDRRLLIGQSTPFKL---TNIGRAAF 793
            |    :|:.:|.|||        ||                       .|..|:   |::|.|..
  Rat   589 L----ENEFIQAAEP--------SD-----------------------GTGGKVYHPTHLGSATL 618

  Fly   794 KAGIDYKRANAIHKELKQAQQQLILTNYLHLLYLVVCFNSNERGDELFPADASI----LFGVYTS 854
            .:.:.......|..:|::|.:..:|.|.||::|||.         .:|....||    .|.::..
  Rat   619 SSSLSPTDTLDIFADLQRAMKGFVLENDLHIVYLVT---------PVFEDWTSIDWYRFFCLWEK 674

  Fly   855 LPLDSQAMFKQLGFTEAHAARLFK------TQSVQGPLSLQLNRLYKVLILADILNLLPIPSVAS 913
            ||...:.:.:.:|..|...||..|      |:.....:::. .|.:..|:|.|:::.:|:..:..
  Rat   675 LPTSMKRVAELVGVEEGFLARCVKGKVVARTERQHRQMAIH-KRFFTSLVLLDLISEIPLKEINQ 738

  Fly   914 KYNVERGTLQHLISQSTAAASAIVRLCEELEEFWCYKPLFERILHKMDRCGTF----ELEPLMEL 974
            ||...||.:|.|...:...|..|......|.  |   ...|.:|.:..:..||    ||..|:.:
  Rat   739 KYGCNRGQIQSLQQSAAVYAGMITVFSNRLG--W---HNMELLLSQFQKRLTFGIQRELCDLIRV 798

  Fly   975 PAVKINRARQLYAAGFQTIGDIARVRPSHLVQSL-EHMPLRVATEIVSAAKIILMKKLDHLEEET 1038
            .::...|||.|||:||.|:.|:||.....:..:| :.:|.:.|           .|.:|..||..
  Rat   799 SSLNAQRARFLYASGFLTVADLARADTVEVEAALKDALPFKSA-----------RKAVDEEEEAA 852

  Fly  1039 E 1039
            |
  Rat   853 E 853

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mus301	NP_648178.1	DEXHc_POLQ-like	247..449	CDD:350784	85/219 (39%)
		BRR2	255..828	CDD:440817	209/629 (33%)
Polq	NP_001099348.1	BRR2	77..660	CDD:440817	215/653 (33%)
		DnaQ_like_exo	1844..2044	CDD:447876
		DNA_pol_A_theta	2050..2542	CDD:176475