DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mus301 and Poln

DIOPT Version :9

Sequence 1:	NP_648178.1	Gene:	mus301 / 38905	FlyBaseID:	FBgn0002899	Length:	1051	Species:	Drosophila melanogaster
Sequence 2:	NP_862905.1	Gene:	Poln / 272158	MGIID:	2675617	Length:	866	Species:	Mus musculus

Alignment Length:	328	Identity:	59/328 - (17%)
Similarity:	121/328 - (36%)	Gaps:	68/328 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 DLLDGRKEELFGTQATTSTNKMTQSGSDDGLGLFADTSFPSAQSVPPNSASKPDEASAPTDKHQI 116
            |.:|.|.|     ..:|:|:|:.:..|.. ..:.|:  ....||:   ....|:.....|.:..|
Mouse    34 DFMDSRNE-----GESTNTSKVAKKSSVH-YSVLAE--HEETQSL---GTKNPESLITQTPRGSI 87

  Fly   117 DLADEENADKLFKKINLNDL--SIAEMEDIFHGADDFSDPMVQNTQLFLDAMTFKKPKTPEKLLA 179
            :|..:.:..||..:::...:  ||:.:     |...:..|........|..|..|:....::.:.
Mouse    88 ELCPQPSITKLTCQLSAGQVQNSISSL-----GLSSYLIPQCDQEASVLPNMEHKRQHFLKENIG 147

  Fly   180 PLKDDSMSFISKSVIEGLVQGTQYVTCEELKNQSLLDPVNWETQAFADFEKNNQDIDKFPSKGEF 244
            ....|:.|...|           |:||.:...::         ......||:....:.:|:..:.
Mouse   148 KEDKDNSSLKRK-----------YITCSKSSEKA---------SKHTALEKDTDGTESWPNSRDT 192

  Fly   245 YGLPDKVKKMILEHKGINSLYEWQDECLNLPAIRQRKNLIYALPTSGGKTLVAEILMLRELLCRE 309
            ..|.::    :.:.:.:..|.:.|    .:.|::|...|:..|....|.|   ::.....|.|..
Mouse   193 RALGER----LCDVRYLGDLAKAQ----LMDALKQAAALVVTLMYKDGST---QLSAKEALTCTV 246

  Fly   310 RNVLFILPYVSIVQEKVSAMSPF--AIDLDFIVEEYTAGKGKC-------PP--QPRRKRRSLFI 363
            :.::.:|.  |.|......:...  |::.|||.|::      |       .|  .|:::..|||:
Mouse   247 KGIVVLLK--SHVGNSTLTLPAHGGALEKDFISEDH------CVYIHTEHSPFWDPKQEAHSLFV 303

  Fly   364 ASI 366
            .:|
Mouse   304 RNI 306

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mus301	NP_648178.1	BRR2	247..998	CDD:224125	26/131 (20%)
mus301	NP_648178.1	DEXHc_POLQ-like	247..449	CDD:350784	26/131 (20%)
Poln	NP_862905.1	PolA	261..854	CDD:223820	12/52 (23%)
		DnaQ_like_exo	<314..437	CDD:299142
		DNA_pol_A_theta	444..856	CDD:176475
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0749
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900