Protein Alignment mus301 and hrq1

DIOPT Version :10

• Sequence 1: NP_648178.1
• Gene: mus301 / 38905
• FlyBaseID: FBgn0002899
• Length: 1051
• Species: Drosophila melanogaster
• Sequence 2: NP_594448.2
• Gene: hrq1 / 2542036
• PomBaseID: SPAC23A1.19C
• Length: 1063
• Species: Schizosaccharomyces pombe
• Alignment Length: 1004
• Identity: 204/1004 - (20%)
• Similarity: 354/1004 - (35%)
• Gaps: 326/1004 - (32%)

  Fly   101 ASKPDEASAPTDKHQIDLADEENADKLFKKINLNDLSIA---EMEDIFHGADDF--------SDP 154
            :||......||.|..|..          :|::.|:|..|   ..:....|..::        .||
pombe   164 SSKRRRREGPTMKANIQR----------QKLDFNNLKKAIELRNQKFLQGIKEYIKKCQLTELDP 218

  Fly   155 MVQNTQLFLDAMTFKKPKTPEKLLAPLKDDSMSFISKSVIEGLVQGTQYVTCEELKNQSLLDPVN 219
                ||..|         |..:...|:..||.| |....||.....|:..:.|||.|: :....:
pombe   219 ----TQQLL---------TQSRKNQPVPPDSPS-IPNDSIENCNLNTKACSIEELLNE-IASESS 268

  Fly   220 WETQAFADFEKNNQDIDKFPSKGEFYG-----LPDKVKKMILEHKGINSLYEWQDECLNLPAIRQ 279
            :|.|..      .:.:..:|:....||     |..::...:...:.|...|:.|.:.:|  .:..
pombe   269 YEGQIV------QEALHTYPAVEAQYGALSRPLSQELINALYTSRNIEKTYKHQADAIN--HLWN 325

  Fly   280 RKNLIYALPTSGGKTLVAEILMLRELL-CRERNVLFILPYVSIVQEKVSAMSPFAIDL------- 336
            ..::|.:..||.||:|:.:|.:|:.|| ..:....|:.|..|:.|::..::    ||:
pombe   326 GFHVIVSTSTSSGKSLIYQIPILQSLLEDNQSTAFFVFPTKSLAQDQKKSL----IDILSYMPTL 386

  Fly   337 -DFIVEEYTAGKGKCPPQPRRKRRSLFIASIEKGAVLM----DSLIDVQRPH---------EIGL 387
             :..|:.:   .|..|.:.|.        ||.:.|.::    |.|.....|:         .:.|
pombe   387 KNIRVDTF---DGDTPLESRE--------SIIRSANIIFTNPDMLHQTILPNANRWYYFFKNLKL 440

  Fly   388 VVVDELHLIGEKGRGATLEAFLTKVM------FLNANIQIVGMSATIGN-LSEISSFLNAD---- 441
            .|:||.|:.  .|......||:.:.|      |.|:..:.|..||||.: |..:......|
pombe   441 FVLDEAHVY--NGIFGVHVAFVLRRMRRIAEYFGNSQYRFVSCSATIEDPLQHMKKIFGVDNIKL 503

  Fly   442 -VYTRGFRPVELKEYIKCGPDLLEINSAGQTLEEIFVPSRSVEYNYSEAVKRADPDHLAGLISEC 505
             .||..  |...|:::...|..::...          |....:...|||.|         |:.:.
pombe   504 INYTSS--PSGSKKFVMWNPPYVDPKH----------PDDGKKSAISEASK---------LLIKF 547

  Fly   506 APEHC-CLVFCPSRKNCENVALLLSRIVPKHKFFEHRRSEKLDLMDALDKMCGILSPVLAKTLPY 569
            |.:.. .:|||..||.||:    |.|:|.:    |.:..:|.||:..:..
pombe   548 AEKRVRTIVFCRVRKTCES----LMRLVRQ----ELKTKQKGDLLSKIQS--------------- 589

  Fly   570 GIAYHHSGLTTDERKYIETAYRFGVVTVICCTSTLAAGVNLPAKRVIIRA--PYVGQEFLTLCKY 632
                :.:|.|..||:.||:....|.:..|..|:.|..|:::.:...:|..  ||      :|...
pombe   590 ----YRAGYTVQERRKIESEMFNGKLYGIIATNALELGIDIGSLDAVITIGFPY------SLSNL 644

  Fly   633 KQMVGRAGRAGLGEAGESILIAQSKDNLLVGQMLFSPMDKALSSLDQNEAVGLQSLILSVVGLNL 697
            :|..|||||             ::|.:|.|..:...|:|:..          |:..||.....|
pombe   645 RQQFGRAGR-------------RNKSSLAVYIVETFPVDQFY----------LKHPILIHTQPN- 685

  Fly   698 AECRRDLNRLVNSTLLS--VQAKSLEVAVNEIVLRILREMFKNKVLQLAE--------------- 745
            ||...|   |.|..||:  :|..:.|:.:|   :|...:.|.|::..:.|
pombe   686 AELTLD---LTNEVLLASHLQCAAYELPIN---IRSDEKFFGNQIQDICEANLEMVEESYRPHPK 744

  Fly   746 ----PQAKSKIN--SSDIITSQDVSQANRPAGDRRLLIGQSTPFKLTNIGRAAFKAGIDYKRANA 804
                |.::.:|.  |.|:.|..||:      .|:.:::....||      |.|..|   |:.|..
pombe   745 YLPFPASQVRIRSVSEDMFTLVDVT------NDKNVILELLEPF------RVALTA---YEGAVY 794

  Fly   805 IHKELKQAQQQLILTNYLHLLYLVVCFNSNERGDELFPADASILFGVYTSLPLDSQAMFKQLGFT 869
            :               |....:::...|.|:|              :.|:..:|.:....|..||
pombe   795 V---------------YQGKTFIIRLLNINKR--------------IITAHQVDVEWSTLQRDFT 830

  Fly   870 EAHAARLFKTQSVQGPLSLQLNRL---------YKVLILADILNLLPIPSVASKYNVE---RGTL 922
            :....|....:::.|..::....:         :||....|||:::.|    :.:.||   ||
pombe   831 DVDPVRSLMKKTMHGSTNIYFGAVKATLHVFGYFKVNKQKDILDVVDI----TDHPVEIDSRG-- 889

  Fly   923 QHLISQSTAAASAIVRLCEELEEFWCYKPLFERILHKMDRCGTFELEPLMELPAVKINRARQLYA 987
                                   ||...|              :.:..::.|.  |||.|..::|
pombe   890 -----------------------FWIDVP--------------WHIIEVLSLK--KINGAASIHA 915

  Fly   988 AGFQTIGDIARVRPSHLVQSLEHMPLRVA 1016
            |             .|.:.||  ||:.::
pombe   916 A-------------QHALLSL--MPIFIS 929

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mus301	NP_648178.1	DEXHc_POLQ-like	247..449	CDD:350784	51/235 (22%)
		BRR2	255..828	CDD:440817	134/632 (21%)
hrq1	NP_594448.2	CDT1	51..222	CDD:215014	15/71 (21%)
		YprA	255..1035	CDD:440818	179/889 (20%)