Protein Alignment mus301 and Helq

DIOPT Version :10

• Sequence 1: NP_648178.1
• Gene: mus301 / 38905
• FlyBaseID: FBgn0002899
• Length: 1051
• Species: Drosophila melanogaster
• Sequence 2: XP_006534885.1
• Gene: Helq / 191578
• MGIID: 2176740
• Length: 1141
• Species: Mus musculus
• Alignment Length: 1058
• Identity: 392/1058 - (37%)
• Similarity: 573/1058 - (54%)
• Gaps: 151/1058 - (14%)

  Fly     4 KHNLCKKRSLDLSEESTSESHAKRQCTENLFWPEGEDDDSF---------FSNAHLEDLLDGRKE 59
            |:||.....::|::..|||...|:...:....||...|.||         |.|..       ...
Mouse   187 KNNLRVTTVINLTDPETSEHGQKQSHLDVPAEPEPGSDLSFDVPSSQILYFENPQ-------NSP 244

  Fly    60 ELFGTQATTSTNKMTQSGSDDGLGLFADTSFPSAQSVPPNSASKPDEASAPTDKHQIDLADEENA 124
            |..|...|..||...|..|.:.|     .|..:.|..|.|            |...:..|.|.:.
Mouse   245 EALGDPCTKKTNGDPQKSSHEEL-----VSSHTEQPEPNN------------DFSNVRAASESSR 292

  Fly   125 DKLFKKINLNDLSIAEMEDIFHGADDFSDPMVQNTQLFLDAMTFKKPKTPEKLLAPLKDDSMSFI 189
            .|..|                   |.....|..|.:    |.|...|:: :.|...|..:.:|..
Mouse   293 RKSLK-------------------DHLKSTMAGNAR----AQTPAFPRS-KHLREALLSEEISVA 333

  Fly   190 SKSVIEGLVQGTQYVTCEELKNQSLLDPVNWETQAFADFEKNNQDIDKFPSKGEFYGLPDKVKKM 254
            .|::                                   |..:.|:      |.||.||.||:.:
Mouse   334 KKAI-----------------------------------ESPSDDL------GPFYSLPSKVRDL 357

  Fly   255 ILEHKGINSLYEWQDECLNLPAIRQRKNLIYALPTSGGKTLVAEILMLRELLCRERNVLFILPYV 319
            .::.|||..||:||..||.|.::::||||||:||||||||||||||||:|||||:::||.|||||
Mouse   358 YVQLKGIKKLYDWQHTCLTLRSVQERKNLIYSLPTSGGKTLVAEILMLQELLCRQKDVLMILPYV 422

  Fly   320 SIVQEKVSAMSPFAIDLDFIVEEYTAGKGKCPPQPRRKRRSLFIASIEKGAVLMDSLIDVQRPHE 384
            :|||||:|::|.|.|:|.|.||||...||:.||..||:::||:||:|||...|:::||:..|...
Mouse   423 AIVQEKISSLSSFGIELGFFVEEYAGSKGRFPPIKRREKKSLYIATIEKAHSLVNALIETSRLST 487

  Fly   385 IGLVVVDELHLIGEKGRGATLEAFLTKVMFLNANIQIVGMSATIGNLSEISSFLNADVYTRGFRP 449
            :|||||||||:|||..|||.||..|.||::.:...||:|||||:.|:.::.:||.|:.||..|||
Mouse   488 LGLVVVDELHMIGEGSRGAILEMTLAKVLYTSKTTQIIGMSATLNNVEDLQAFLKAEYYTSQFRP 552

  Fly   450 VELKEYIKCGPDLLEINSA---GQTLEEIFVPSRSVEYNYSEAVKRADPDHLAGLISECAPEHCC 511
            |||||::|....:.|::|.   |.|.      ||.:.|.||||:|:.|||.|..|::|..|.:.|
Mouse   553 VELKEFLKVNDTIYEVDSQAADGMTF------SRLLSYKYSEALKKMDPDRLVALVTEVIPNYSC 611

  Fly   512 LVFCPSRKNCENVALLLSRIVPKHKFFEHRRSEKLDLMDAL-----DKMCGILSPVLAKTLPYGI 571
            ||||||:|||||||.:|.:.:.| .:..||..||.:::.:|     .|:|    |||.:|:|:||
Mouse   612 LVFCPSKKNCENVAEMLCKFLSK-DYLNHREKEKCEVIKSLRNIGNGKVC----PVLKRTVPFGI 671

  Fly   572 AYHHSGLTTDERKYIETAYRFGVVTVICCTSTLAAGVNLPAKRVIIRAPYVGQEFLTLCKYKQMV 636
            ||||||||::|||.:|.||..||:.::.|||||||||||||:|||:|||||...||...:|||||
Mouse   672 AYHHSGLTSEERKLLEEAYSTGVLCLLTCTSTLAAGVNLPARRVILRAPYVANTFLKRNQYKQMV 736

  Fly   637 GRAGRAGLGEAGESILIAQSKDNLLVGQMLFSPMDKALSSLDQNEAVGLQSLILSVVGLNLAECR 701
            |||||||:..||||||:.|.||...|.:::..|::...|.|.:....|:|:|.||::||.:|...
Mouse   737 GRAGRAGIDTAGESILLLQEKDKQQVLELISGPLETCCSHLVEEFTKGIQALFLSLIGLKIAASL 801

  Fly   702 RDLNRLVNSTLLSVQAKSL--EVAVNEIVLRILREMFKNKVLQLAEPQAKSKINSSDIITSQDVS 764
            .|:.:.::.|...||.|.|  |.::.||.:..|..:.:..:||
Mouse   802 GDIYQFMSGTFFGVQQKILLKEKSLWEITVDALEHLTEKGLLQ---------------------- 844

  Fly   765 QANRPAGDRRLLIGQSTPFKLTNIGRAAFKAGIDYKRANAIHKELKQAQQQLILTNYLHLLYLVV 829
              ....||..   |....|::|.:|:|:||..||....:.::::||:..:.|:|.:.|||:||..
Mouse   845 --KDSCGDNE---GLECHFRITKLGQASFKGAIDLAYCDTLYRDLKKGLEGLVLESLLHLIYLTT 904

  Fly   830 CFNSNERGDELFPADASILFGVYTSLPLDSQAMFKQLGFTEAHAARLFKTQSVQGPLSLQ-LNRL 893
            .::...:.:    .|..:.|..:..|....|.:...||.:|:...:....|:|:..:... :|||
Mouse   905 PYDLAAQSE----PDWMVYFKQFGQLSPTEQNVAALLGVSESFIGKKAAGQAVRKKVDKNVVNRL 965

  Fly   894 YKVLILADILNLLPIPSVASKYNVERGTLQHLISQSTAAASAIVRLCEELEEFWCYKPLFERILH 958
            |...:|..:|....:.||:.|:|:.||.:|:|:..:.:.:|.::..||||||||.||.|...:..
Mouse   966 YLSFVLYSLLKETNVWSVSEKFNLPRGYIQNLLMGAASFSSCVLHFCEELEEFWVYKALLVELTK 1030

  Fly   959 KMDRCGTFELEPLMELPAVKINRARQLYAAGFQTIGDIARVRPSHLVQSLEHMPLRVATEIVSAA 1023
            |:..|...||.||||:..|...||:|||.||:::|..:|...|..||::::|:..|.|.:|||:|
Mouse  1031 KLTYCVKAELIPLMEVTGVLEGRAKQLYNAGYRSIMHLANANPEVLVKTIDHLSRRQARQIVSSA 1095

  Fly  1024 KIILMKKLDHLEEETENL 1041
            |::|.:|.:.|:.|.|.|
Mouse  1096 KMLLHEKAEALQGEAEEL 1113

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mus301	NP_648178.1	DEXHc_POLQ-like	247..449	CDD:350784	114/201 (57%)
		BRR2	255..828	CDD:440817	270/582 (46%)
Helq	XP_006534885.1	PHA03307	35..>327	CDD:223039	40/187 (21%)
		BRR2	350..917	CDD:440817	276/608 (45%)
		DEXHc_POLQ-like	350..552	CDD:350784	114/201 (57%)
		HHH_5	1043..1096	CDD:434010	22/52 (42%)