Protein Alignment mus301 and snrp-200

DIOPT Version :10

• Sequence 1: NP_648178.1
• Gene: mus301 / 38905
• FlyBaseID: FBgn0002899
• Length: 1051
• Species: Drosophila melanogaster
• Sequence 2: NP_001366952.1
• Gene: snrp-200 / 174901
• WormBaseID: WBGene00012896
• Length: 2145
• Species: Caenorhabditis elegans
• Alignment Length: 1203
• Identity: 257/1203 - (21%)
• Similarity: 445/1203 - (36%)
• Gaps: 363/1203 - (30%)

  Fly     6 NLCKKRSLDLSEESTSESHAKRQCTENLFWPEGEDDDSFFSNAHLEDLLDGRKEELFGTQAT-TS 69
            ||.||.| |.|.|..::             |||:.|  .:.|..:....|..:||..|.... ..
 Worm   169 NLSKKIS-DFSIEEENK-------------PEGDGD--IYENEGVNVQFDSDEEEDDGGMVNEIK 217

  Fly    70 TNKMTQSGSDDGLGLFADTSFPSAQSVPPNSASKPDEASA-------PTDKHQIDLADEENADKL 127
            .:...:|..::|:    ||.:.:  ::..:.....||..|       ..|.|.|    :.:..|.
 Worm   218 GDSEEESEEEEGV----DTDYTA--TLKGDGHLTEDEQKARGILHPRDIDAHWI----QRSLAKY 272

  Fly   128 FKKINLNDLSIAEMED------IFHGADD-----------------FSDPMVQNTQLFLDAMTFK 169
            ||     |..||:.:.      :.:.|||                 |...:.||..:.|.....:
 Worm   273 FK-----DPLIAQQKQTEVIGILKNAADDRDAENQLVLLLGFDQFEFIKCLRQNRLMILYCTLLR 332

  Fly   170 KPKTPEKLLAPLKDDSMSFISKSVIEGLVQGTQYVTCEELKNQSLLDPVNWETQAFADFEKNNQD 234
            :....|:|  .::||..|......|..|:|.|                   :..:....||:.:|
 Worm   333 QANEKERL--QIEDDMRSRPELHPILALLQET-------------------DEGSVVQVEKSKRD 376

  Fly   235 IDKFP----------SKGEFYG-------------------------LPD----KVKKMILE-H- 258
            .:|..          |.|::..                         |||    :.||...| |
 Worm   377 AEKSKKAATAANEAISAGQWQAGRKMLDLNDLTFSQGSHLMSNKRCELPDGSYRRQKKSYEEIHV 441

  Fly   259 --------------KGINSLYEWQD------ECLNL-------PAIRQRKNLIYALPTSGGKTLV 296
                          ..::.|.:|..      :.||.       .|:|.:::|:...||..|||.|
 Worm   442 PALKPRPFAEGEKLVSVSELPKWAQPAFDGYKSLNRIQSRLCDSALRSKEHLLLCAPTGAGKTNV 506

  Fly   297 AEILMLREL----------LCRERNVLFILPYVSIVQEKVSAMS----PFAI-------DLDFIV 340
            |.:.||:|:          ...|..:::|.|..|:|||.|.:.|    ||.|       |.....
 Worm   507 ALLTMLQEIGNHLAEDGSVKLDEFKIVYIAPMKSLVQEMVGSFSKRLAPFGITVGEMTGDAQMSK 571

  Fly   341 EEYTAGKG-KCPPQPRRKRRSLFIASIEKGAVLMDSLIDVQRPHE--IGLVVVDELHLIGEKGRG 402
            |::.|.:. .|.|:.       :.....||.         :|.:.  :.|:::||:||:.: .||
 Worm   572 EQFMATQVIVCTPEK-------YDVVTRKGG---------ERAYNQMVRLLIIDEIHLLHD-DRG 619

  Fly   403 ATLEAFLTK-VMFLNAN---IQIVGMSATIGNLSEISSFL-----NADVYTRGFRPVEL------ 452
            ..||:.:.: :..:..|   .::||:|||:.|..::::||     :...:...:|||.|
 Worm   620 PVLESIVVRTIRQMEQNHDECRLVGLSATLPNYQDVATFLRVKPEHLHFFDNSYRPVPLEQQYIG 684

  Fly   453 ---KEYIKCGPDLLEI------NSAGQTLEEIFVPSRSVEYNYSEAVKRA--DPDHLAGLISECA 506
               |:.:|....:.|:      ..||::...:||.||......::|::.|  :.|.|:..:
 Worm   685 VTEKKALKRFQAMNEVVYDKIMEHAGKSQVLVFVHSRKETAKTAKAIRDACLEKDTLSAFM---- 745

  Fly   507 PEHCCLVFCPSRKNCENVALLLSRIVPKHKFFEHRRSEKLDLMDALDKMCGILSPVLAKTLPYGI 571
                       |:...:..:|.:         |..:::.|||.|               .||||.
 Worm   746 -----------REGSASTEILRT---------EAEQAKNLDLKD---------------LLPYGF 775

  Fly   572 AYHHSGLTTDERKYIETAYRFGVVTVICCTSTLAAGVNLPAKRVIIRA-----PYVGQ-EFLTLC 630
            |.||:|:...:|..:|..:....:.|:..|:|||.||||||..|||:.     |..|: ..|...
 Worm   776 AIHHAGMNRVDRTLVEDLFADRHIQVLFSTATLAWGVNLPAHTVIIKGTQIYNPEKGRWTELGAL 840

  Fly   631 KYKQMVGRAGRAGLGEAGESILIAQSKDNLLVGQMLFSPMDKALSSLDQNEAVGLQSLILSVVGL 695
            ...||:|||||....:.||.|||..           .|.:...||.:  |:.:.::|.::|
 Worm   841 DIMQMLGRAGRPQYDDRGEGILITN-----------HSELQYYLSLM--NQQLPVESQMVS---- 888

  Fly   696 NLAECRRDLNRLVNSTLLSVQAKSLEVAVNEIVLRIL-REMFKNKVLQ-LAEPQAKS----KINS 754
                   .|..::|:.::.....|:..|.|.:....| ..|.||..|. :...||::    :...
 Worm   889 -------RLTDMLNAEVVLGTVSSVSEATNWLGYTFLFVRMLKNPTLYGITHEQARADPLLEQRR 946

  Fly   755 SDIITSQDV--SQANRPAGDRRLLIGQSTPFKLTNIGRAAFK-------------------AGID 798
            :|:|.:..|  .:|.....|:|..|.|:     |.:||.|..                   :.||
 Worm   947 ADLIHTACVLLDKAGLIKYDKRSGIIQA-----TELGRIASHFYCTYESMQTYNKLLVETCSDID 1006

  Fly   799 YKRANAIHKELK----QAQQQLILTNYLHLLYLVVCFNSNERGDELFPADASILFGVYTS-LPLD 858
            ..|..::..|.|    :.:::|.|........:.:..|.:|..     |..::|...|.| |.|:
 Worm  1007 LFRIFSMSSEFKLLSVRDEEKLELQKMAEHAPIPIKENLDEAS-----AKTNVLLQAYISQLKLE 1066

  Fly   859 SQAMFKQLGFTEAHAARLFKTQSVQGPLSLQLNRLYKVLILADILNLLPIPSVASKYNVER--GT 921
            ..|:...:.|....|.|||:.             |:::::......|........|...:|  |:
 Worm  1067 GFALQADMVFVAQSAGRLFRA-------------LFEIVLWRGWAGLAQKVLTLCKMVTQRQWGS 1118

  Fly   922 LQHLISQSTAAASAIVRLCEELEEFWCYKPLFERILHKMDRCGTFELEPLMELPAVKINRARQLY 986
            |..| .|.....|.:||..::..    |.  |:| |:.:|:   .:|..|:::|.:    .:.|
 Worm  1119 LNPL-HQFKKIPSEVVRSIDKKN----YS--FDR-LYDLDQ---HQLGDLIKMPKM----GKPL- 1167

  Fly   987 AAGFQTIGDIARVRPSHLVQSLEHMPLRVATEI 1019
               |:.|....::..:.|:|.:....:|:...|
 Worm  1168 ---FKFIRQFPKLEMTTLIQPITRTTMRIELTI 1197

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mus301	NP_648178.1	DEXHc_POLQ-like	247..449	CDD:350784	62/267 (23%)
		BRR2	255..828	CDD:440817	157/688 (23%)
snrp-200	NP_001366952.1	Helicase_PWI	254..359	CDD:436309	22/115 (19%)
		BRR2	458..1010	CDD:440817	150/636 (24%)
		DEXHc_Brr2_1	458..670	CDD:350777	55/228 (24%)
		Sec63	974..1278	CDD:460740	51/266 (19%)
		BRR2	1313..1848	CDD:440817
		DEXHc_Brr2_2	1319..1509	CDD:350779
		SEC63	1808..2127	CDD:214744