Protein Alignment mus301 and mus301

DIOPT Version :10

• Sequence 1: NP_648178.1
• Gene: mus301 / 38905
• FlyBaseID: FBgn0002899
• Length: 1051
• Species: Drosophila melanogaster
• Sequence 2: XP_551895.4
• Gene: mus301 / 1280395
• VectorBaseID: AGAMI1_008774
• Length: 1210
• Species: Anopheles gambiae
• Alignment Length: 1125
• Identity: 404/1125 - (35%)
• Similarity: 619/1125 - (55%)
• Gaps: 184/1125 - (16%)

  Fly    14 DLSEESTSESHAKRQ-CTE---NLFWPEGEDDDSF------------------------FSNAH- 49
            |.:..:.|.|..|.. |:|   |..:.:.||:|..                        .||.|
Mosquito   163 DANGSAASRSPTKDSGCSERRTNTGFEDDEDEDYLLDVVIPCGQQETSTDHFIRDKMRRLSNVHT 227

  Fly    50 -----LEDLLDGRKEELFGTQATTST-NKMTQSGSDDGLGLFADTSFPSAQSVPP--------NS 100
                 |..:|:....|:|...|..|. .::.||..|:           :::.:.|        |.
Mosquito   228 ASQVALGQMLEDDAFEVFTNHAICSQYMRLDQSVVDE-----------ASEKIDPILGSQIGRNG 281

  Fly   101 ASKPDEASAPTDKHQIDLADEENADKLFKKINLNDLSIAEMEDIFHGADDFSDPMVQNTQLFLDA 165
            ..:|...:.|..    |:.|.:.          :.|.::|::.||...:          :..||.
Mosquito   282 VGRPSSPNTPAR----DVTDSQQ----------HRLQVSEVQRIFENCE----------RTLLDL 322

  Fly   166 MTFKKPKTPEKLLAPLKDDSMSFISKSVIEGLVQGTQYVTCEELKNQSLLDPVNWETQAFADFEK 230
            ..          :||....|...||.|                      |..:||:
Mosquito   323 TN----------IAPDGGGSQPRISSS----------------------LAAINWD--------- 346

  Fly   231 NNQDI-------------------------DKFPSKGEFYGLPDKVKKMILEHKGINSLYEWQDE 270
              ::|                         ..|..||.|:|||:.|::::.:.:||:.||:||.|
Mosquito   347 --EEIHHTTALLPVAVGMGPPPGNGAPRVSSLFLEKGPFFGLPNTVRRILRDFRGIDDLYDWQRE 409

  Fly   271 CLNLPAIRQRKNLIYALPTSGGKTLVAEILMLRELLCRERNVLFILPYVSIVQEKVSAMSPFAID 335
            ||.||||::|:|||||||||||||||||||||||::||.|||:||:||||:.|||:.|:||||::
Mosquito   410 CLALPAIQERRNLIYALPTSGGKTLVAEILMLREIICRLRNVIFIVPYVSLAQEKMIALSPFALE 474

  Fly   336 LDFIVEEYTAGKGKCPPQPRRKRRSLFIASIEKGAVLMDSLIDVQRPHEIGLVVVDELHLIGEKG 400
            |.|::|||:.|||:|||:.|||:.::|:.:|||..:|:|||::|.|.:||||:|:||||:|||:.
Mosquito   475 LQFLLEEYSGGKGQCPPRKRRKKNTIFVCTIEKALLLLDSLVEVGRANEIGLIVIDELHMIGEQR 539

  Fly   401 RGATLEAFLTKVMFLNANIQIVGMSATIGNLSEISSFLNADVYTRGFRPVELKEYIKCGPDLLEI 465
            |||.||..:|||..|.|.|||||||||||||:|::.|:.||||:|.||||||||::|||.||..:
Mosquito   540 RGACLEMMITKVQVLRAGIQIVGMSATIGNLTEVARFMLADVYSRDFRPVELKEFVKCGDDLYAV 604

  Fly   466 NSAGQ----TLEEIFVPSRSVEY-NYSEAVKRADPDHLAGLISECAPEHCCLVFCPSRKNCENVA 525
            .|.||    :.|.:|...|::|: :.||.::|.|.||:..||.|..||..||||||::..||::.
Mosquito   605 RSKGQADGGSAENVFGEKRALEFADCSEELRRLDTDHVVRLILEVIPESSCLVFCPTKSKCESLC 669

  Fly   526 LLLSRIVPKHKFFEHRRSEKLDLMDALDKMCGILSPVLAKTLPYGIAYHHSGLTTDERKYIETAY 590
            .||:..:|. :..|||..||..::.:| |..|.::|||.:....|:||||:|||.|||:.||.||
Mosquito   670 ALLANHLPA-RLAEHRAEEKEQIIRSL-KEDGSIAPVLPQAFRVGVAYHHAGLTQDERRTIEDAY 732

  Fly   591 RFGVVTVICCTSTLAAGVNLPAKRVIIRAPYVGQEFLTLCKYKQMVGRAGRAGLGEAGESILIAQ 655
            |.|::::|.|||||||||||||||||||:||:|..||:|.:||||||||||||.||.||||||..
Mosquito   733 RAGILSLIVCTSTLAAGVNLPAKRVIIRSPYIGNSFLSLSRYKQMVGRAGRAGFGETGESILICA 797

  Fly   656 SKDNLLVGQMLFSPMDKALSSLDQNEAVGLQSLILSVVGLNLAECRRDLNRLVNSTLLSVQAKSL 720
            .:|...|.:||.:|||.|.|:|..::....:|||||.:||:|.|.|..|..||..|||:.||:..
Mosquito   798 QRDIPQVCEMLCAPMDIAESALIADDRAYFKSLILSAIGLDLCESRDALQALVRCTLLAQQAERR 862

  Fly   721 EVAVNEIVLRILREMFKNKVLQ--------------------LAEPQAKSKINSSDII------T 759
            .:.:..:....:.::::...::                    :.|.::.:|..||...      |
Mosquito   863 SIDLAAVTDETIVQLYQGNAIKARHDSCLRNPPNMLVEIGTAVEEDRSPTKTGSSAPYDGAAGPT 927

  Fly   760 SQDVSQANRPAGDRRLLIGQSTPFKLTNIGRAAFKAGIDYKRANAIHKELKQAQQQLILTNYLHL 824
            ...|.:|....|.....|.:::|.::..:|:||.:||.:.::|...:.|:|...::|.:.:...|
Mosquito   928 FVRVHKAAAHPGKVIKTIQRTSPLEVNRLGKAAIRAGFNMEKAVRFYDEMKVLGERLCVLDEYDL 992

  Fly   825 LYLVVCFNSNERGDELFPADASILFGVYTSLPLDSQAMFKQLGFTEAHAARLFKTQSVQGPLSLQ 889
            |:|::..:..|  .:|.|.|..:|....|:   :...:.::.|......|::...:...|.:..:
Mosquito   993 LHLILLEDGRE--VQLKPDDFIVLVNQLTN---EQLKIAERYGINNGLIAKILTRRVASGDMVSK 1052

  Fly   890 LNRLYKVLILADILNLLPIPSVASKYNVERGTLQHLISQSTAAASAIVRLCEELEEFWCYKPLFE 954
            :.|..:|||:.::....|:..|||:|:|..|:||.|::.:...|.:::|:|||:.|.|.:|.|..
Mosquito  1053 MMRFVRVLIVHELWKQTPLAEVASRYHVNAGSLQTLMTSTAGTAFSLLRMCEEIPELWAFKHLLT 1117

  Fly   955 RILHKMDRCGTFELEPLMELPAVKINRARQLYAAGFQTIGDIARVRPSHLVQSLEHMPLRVATEI 1019
            .:..::......||.||:.||:||:.|||||:.||:.|:..|||.....||:::||:..|.|:::
Mosquito  1118 GMTERLTHYCKLELLPLLTLPSVKLGRARQLFRAGYTTLASIARATSRELVETIEHLNYRAASQL 1182

  Fly  1020 VSAAKIILMKKLDHLEEETE 1039
            :.:||..|::::|.|.|:.|
Mosquito  1183 ILSAKAKLLEEVDALREQAE 1202

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mus301	NP_648178.1	DEXHc_POLQ-like	247..449	CDD:350784	126/201 (63%)
		BRR2	255..828	CDD:440817	287/603 (48%)
mus301	XP_551895.4	None