Protein Alignment mus301 and helq

DIOPT Version :10

• Sequence 1: NP_648178.1
• Gene: mus301 / 38905
• FlyBaseID: FBgn0002899
• Length: 1051
• Species: Drosophila melanogaster
• Sequence 2: XP_002939628.2
• Gene: helq / 100485183
• XenbaseID: XB-GENE-993428
• Length: 1000
• Species: Xenopus tropicalis
• Alignment Length: 1062
• Identity: 400/1062 - (37%)
• Similarity: 602/1062 - (56%)
• Gaps: 117/1062 - (11%)

  Fly     5 HNLC--KKRSLDLSEESTSESHAKRQCTENLFWPEGEDDDSFFSN----AHLEDLLDGRKEELFG 63
            |:|.  .|:.::..|:...:.|   :..|:||   || .|||..:    |.::||.:..|.|...
 Frog    23 HSLLTPTKKRMNSREDDNIKCH---ESDEDLF---GE-YDSFAEDLDLLAQVDDLENQEKLEQCN 80

  Fly    64 TQATTST-----------NKMTQSGSDDGLGLFADTSFPSAQSVPPNSASKPDEASAPTDKHQID 117
            |...:|:           :|:..|.|.:...||.......:..:......|..:........|:.
 Frog    81 TFPCSSSDQRPEDPNHNEDKIKHSTSGELSSLFQSGQTARSLRITNELKGKRKDFLDVIPCSQLP 145

  Fly   118 LADEENADKLFKKINLNDLSIAEMEDIFHGADDFSDPMVQNTQLFLDAMTFKKPKTPEKLLAPLK 182
            ..::.|....|..:..|            ||.|.|              ...|.|:       ||
 Frog   146 CNEDSNLRTGFPCVKAN------------GAQDIS--------------RMDKRKS-------LK 177

  Fly   183 DDSMSFISKSVIEGLVQGTQYVTCEELKNQSLLDPVNWETQAFADFEKNNQDIDKFPSKGEFYGL 247
            |...|.::   :...||..:....:|||...||:..:...|..    |.:.|:|    .|.||||
 Frog   178 DHLKSTLA---VNAKVQTPRISRTKELKKAILLEEFDVAQQTV----KTSCDLD----LGPFYGL 231

  Fly   248 PDKVKKMILEHKGINSLYEWQDECLNLPAIRQRKNLIYALPTSGGKTLVAEILMLRELLCRERNV 312
            |.:|:.:|.:.:.|..||:||..||.|.:|::||||||:||||||||||||||:|:|||||:::|
 Frog   232 PSRVRDLIYQFRRIKKLYDWQHTCLTLQSIKERKNLIYSLPTSGGKTLVAEILVLQELLCRQKDV 296

  Fly   313 LFILPYVSIVQEKVSAMSPFAIDLDFIVEEYTAGKGKCPPQPRRKRRSLFIASIEKGAVLMDSLI 377
            |.|||||:||||||..::.|.::|||:||||...:|:.||..||.::||:||:||||..|::|||
 Frog   297 LMILPYVAIVQEKVRGLASFGVELDFLVEEYAGSRGRFPPIKRRTKKSLYIATIEKGHSLINSLI 361

  Fly   378 DVQRPHEIGLVVVDELHLIGEKGRGATLEAFLTKVMFLNANIQIVGMSATIGNLSEISSFLNADV 442
            :..|.:::||:||||||::||..|||.||..|:|:::.:.:|||:|||||:.|::|:.:||.|:.
 Frog   362 ETGRINDLGLIVVDELHMLGEGSRGAILEMTLSKILYTSTSIQIIGMSATLNNVAELQNFLKAEY 426

  Fly   443 YTRGFRPVELKEYIKCGPDLLEINSAGQTLEEIFVPSRSVEYNYSEAVKRADPDHLAGLISECAP 507
            ||..||||||||::|....:.|::|   ..|.....||.:.|.||..:.:.||||:..|::|..|
 Frog   427 YTNNFRPVELKEFVKVRDCIYEVDS---NAENNLTFSRLLNYKYSNNMMKIDPDHVVALVTEVIP 488

  Fly   508 EHCCLVFCPSRKNCENVALLLSRIVPKHKFFEHRRSEKLDLMDALDKM-CGILSPVLAKTLPYGI 571
            .:.||||||::|||||||.::.:.:.| .:.|||.:||.:|:..|..: .|:|..||.:|:|:||
 Frog   489 ANSCLVFCPTKKNCENVAEMICKYLNK-LYVEHREAEKKNLIADLKNIGNGVLCSVLKRTIPFGI 552

  Fly   572 AYHHSGLTTDERKYIETAYRFGVVTVICCTSTLAAGVNLPAKRVIIRAPYVGQEFLTLCKYKQMV 636
            ||||||||:||||.||.||..||:.::.|||||||||||||:|||:|||||..:||...:|||||
 Frog   553 AYHHSGLTSDERKLIEEAYSAGVLCLLACTSTLAAGVNLPARRVILRAPYVANDFLKRAQYKQMV 617

  Fly   637 GRAGRAGLGEAGESILIAQSKDNLLVGQMLFSPMDKALSSLDQNEAVGLQSLILSVVGLNLAECR 701
            |||||||:..|||||||.|.||..||.:::..||:...|:|..|.....|||:||::||.:.:..
 Frog   618 GRAGRAGIDSAGESILIIQEKDKELVQELISKPMENCYSNLMHNSGKDFQSLLLSLIGLKITKTA 682

  Fly   702 RDLNRLVNSTLLSVQAKSLEVAVNEIVLRILREMFKNKVLQLAEPQAKSKINSSDIITSQDVSQA 766
            .::...|:.||.|||...|..|.|  :|.:.:|..:..|
 Frog   683 EEIYSFVSCTLFSVQQSVLCKAKN--LLDVTKESLECLV-------------------------- 719

  Fly   767 NRPAGDRRLLIGQSTP------FKLTNIGRAAFKAGIDYKRANAIHKELKQAQQQLILTNYLHLL 825
                 |:.|:.|::..      |:::.:|.|.:|..||....:.::.:|.:..:.|:|.::||||
 Frog   720 -----DKGLICGKTCSETEQYIFQVSKLGHATYKGCIDLACYDLLYSDLNRGLEGLVLESFLHLL 779

  Fly   826 YLVVCFNSNERGDELFPADASILFGVYTSLPLDSQAMFKQLGFTEAHAARLFKTQSVQ-GPLSLQ 889
            |||:.::...:    |..|..|.|..|.||....|.:...:|..|:..||....|:|: ...::.
 Frog   780 YLVIPYDLVGK----FNPDWMIYFRQYNSLSPVEQKVAASVGIPESFLARKASGQTVKTSANNMV 840

  Fly   890 LNRLYKVLILADILNLLPIPSVASKYNVERGTLQHLISQSTAAASAIVRLCEELEEFWCYKPLFE 954
            :||||...||..:|....|..|::|:::.|||||:|:|.|.:.:|:::..||||:|||.||.|.:
 Frog   841 VNRLYLSFILYTLLKETDIWRVSAKFSIPRGTLQNLLSSSASFSSSVLHFCEELDEFWAYKSLLQ 905

  Fly   955 RILHKMDRCGTFELEPLMELPAVKINRARQLYAAGFQTIGDIARVRPSHLVQSLEHMPLRVATEI 1019
            .:..|:..|...||.||||:..|...||:|||.||:.::..:|...|..:|:.:||:....|.:|
 Frog   906 ELTKKLTYCVKSELIPLMEVAGVMEARAKQLYNAGYTSLAHLANADPEVMVKKIEHLSRHQAKQI 970

  Fly  1020 VSAAKIILMKKLDHLEEETENL 1041
            |.:||:::.:|.:.|:||.:.|
 Frog   971 VFSAKMLVNEKAEALQEEVDEL 992

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mus301	NP_648178.1	DEXHc_POLQ-like	247..449	CDD:350784	111/201 (55%)
		BRR2	255..828	CDD:440817	266/579 (46%)
helq	XP_002939628.2	DEXHc_POLQ-like	231..433	CDD:350784	111/201 (55%)
		BRR2	245..796	CDD:440817	269/591 (46%)
		COG2251	<921..>1000	CDD:441852	27/72 (38%)