Protein Alignment mus301 and helq

DIOPT Version :9

• Sequence 1: NP_648178.1
• Gene: mus301 / 38905
• FlyBaseID: FBgn0002899
• Length: 1051
• Species: Drosophila melanogaster
• Sequence 2: XP_002939628.2
• Gene: helq / 100485183
• XenbaseID: XB-GENE-993428
• Length: 1000
• Species: Xenopus tropicalis
• Alignment Length: 1062
• Identity: 400/1062 - (37%)
• Similarity: 602/1062 - (56%)
• Gaps: 117/1062 - (11%)

  Fly     5 HNLC--KKRSLDLSEESTSESHAKRQCTENLFWPEGEDDDSFFSN----AHLEDLLDGRKEELFG 63
            |:|.  .|:.::..|:...:.|   :..|:||   || .|||..:    |.::||.:..|.|...
 Frog    23 HSLLTPTKKRMNSREDDNIKCH---ESDEDLF---GE-YDSFAEDLDLLAQVDDLENQEKLEQCN 80

  Fly    64 TQATTST-----------NKMTQSGSDDGLGLFADTSFPSAQSVPPNSASKPDEASAPTDKHQID 117
            |...:|:           :|:..|.|.:...||.......:..:......|..:........|:.
 Frog    81 TFPCSSSDQRPEDPNHNEDKIKHSTSGELSSLFQSGQTARSLRITNELKGKRKDFLDVIPCSQLP 145

  Fly   118 LADEENADKLFKKINLNDLSIAEMEDIFHGADDFSDPMVQNTQLFLDAMTFKKPKTPEKLLAPLK 182
            ..::.|....|..:..|            ||.|.|              ...|.|:       ||
 Frog   146 CNEDSNLRTGFPCVKAN------------GAQDIS--------------RMDKRKS-------LK 177

  Fly   183 DDSMSFISKSVIEGLVQGTQYVTCEELKNQSLLDPVNWETQAFADFEKNNQDIDKFPSKGEFYGL 247
            |...|.::   :...||..:....:|||...||:..:...|..    |.:.|:|    .|.||||
 Frog   178 DHLKSTLA---VNAKVQTPRISRTKELKKAILLEEFDVAQQTV----KTSCDLD----LGPFYGL 231

  Fly   248 PDKVKKMILEHKGINSLYEWQDECLNLPAIRQRKNLIYALPTSGGKTLVAEILMLRELLCRERNV 312
            |.:|:.:|.:.:.|..||:||..||.|.:|::||||||:||||||||||||||:|:|||||:::|
 Frog   232 PSRVRDLIYQFRRIKKLYDWQHTCLTLQSIKERKNLIYSLPTSGGKTLVAEILVLQELLCRQKDV 296

  Fly   313 LFILPYVSIVQEKVSAMSPFAIDLDFIVEEYTAGKGKCPPQPRRKRRSLFIASIEKGAVLMDSLI 377
            |.|||||:||||||..::.|.::|||:||||...:|:.||..||.::||:||:||||..|::|||
 Frog   297 LMILPYVAIVQEKVRGLASFGVELDFLVEEYAGSRGRFPPIKRRTKKSLYIATIEKGHSLINSLI 361

  Fly   378 DVQRPHEIGLVVVDELHLIGEKGRGATLEAFLTKVMFLNANIQIVGMSATIGNLSEISSFLNADV 442
            :..|.:::||:||||||::||..|||.||..|:|:::.:.:|||:|||||:.|::|:.:||.|:.
 Frog   362 ETGRINDLGLIVVDELHMLGEGSRGAILEMTLSKILYTSTSIQIIGMSATLNNVAELQNFLKAEY 426

  Fly   443 YTRGFRPVELKEYIKCGPDLLEINSAGQTLEEIFVPSRSVEYNYSEAVKRADPDHLAGLISECAP 507
            ||..||||||||::|....:.|::|   ..|.....||.:.|.||..:.:.||||:..|::|..|
 Frog   427 YTNNFRPVELKEFVKVRDCIYEVDS---NAENNLTFSRLLNYKYSNNMMKIDPDHVVALVTEVIP 488

  Fly   508 EHCCLVFCPSRKNCENVALLLSRIVPKHKFFEHRRSEKLDLMDALDKM-CGILSPVLAKTLPYGI 571
            .:.||||||::|||||||.::.:.:.| .:.|||.:||.:|:..|..: .|:|..||.:|:|:||
 Frog   489 ANSCLVFCPTKKNCENVAEMICKYLNK-LYVEHREAEKKNLIADLKNIGNGVLCSVLKRTIPFGI 552

  Fly   572 AYHHSGLTTDERKYIETAYRFGVVTVICCTSTLAAGVNLPAKRVIIRAPYVGQEFLTLCKYKQMV 636
            ||||||||:||||.||.||..||:.::.|||||||||||||:|||:|||||..:||...:|||||
 Frog   553 AYHHSGLTSDERKLIEEAYSAGVLCLLACTSTLAAGVNLPARRVILRAPYVANDFLKRAQYKQMV 617

  Fly   637 GRAGRAGLGEAGESILIAQSKDNLLVGQMLFSPMDKALSSLDQNEAVGLQSLILSVVGLNLAECR 701
            |||||||:..|||||||.|.||..||.:::..||:...|:|..|.....|||:||::||.:.:..
 Frog   618 GRAGRAGIDSAGESILIIQEKDKELVQELISKPMENCYSNLMHNSGKDFQSLLLSLIGLKITKTA 682

  Fly   702 RDLNRLVNSTLLSVQAKSLEVAVNEIVLRILREMFKNKVLQLAEPQAKSKINSSDIITSQDVSQA 766
            .::...|:.||.|||...|..|.|  :|.:.:|..:..|
 Frog   683 EEIYSFVSCTLFSVQQSVLCKAKN--LLDVTKESLECLV-------------------------- 719

  Fly   767 NRPAGDRRLLIGQSTP------FKLTNIGRAAFKAGIDYKRANAIHKELKQAQQQLILTNYLHLL 825
                 |:.|:.|::..      |:::.:|.|.:|..||....:.::.:|.:..:.|:|.::||||
 Frog   720 -----DKGLICGKTCSETEQYIFQVSKLGHATYKGCIDLACYDLLYSDLNRGLEGLVLESFLHLL 779

  Fly   826 YLVVCFNSNERGDELFPADASILFGVYTSLPLDSQAMFKQLGFTEAHAARLFKTQSVQ-GPLSLQ 889
            |||:.::...:    |..|..|.|..|.||....|.:...:|..|:..||....|:|: ...::.
 Frog   780 YLVIPYDLVGK----FNPDWMIYFRQYNSLSPVEQKVAASVGIPESFLARKASGQTVKTSANNMV 840

  Fly   890 LNRLYKVLILADILNLLPIPSVASKYNVERGTLQHLISQSTAAASAIVRLCEELEEFWCYKPLFE 954
            :||||...||..:|....|..|::|:::.|||||:|:|.|.:.:|:::..||||:|||.||.|.:
 Frog   841 VNRLYLSFILYTLLKETDIWRVSAKFSIPRGTLQNLLSSSASFSSSVLHFCEELDEFWAYKSLLQ 905

  Fly   955 RILHKMDRCGTFELEPLMELPAVKINRARQLYAAGFQTIGDIARVRPSHLVQSLEHMPLRVATEI 1019
            .:..|:..|...||.||||:..|...||:|||.||:.::..:|...|..:|:.:||:....|.:|
 Frog   906 ELTKKLTYCVKSELIPLMEVAGVMEARAKQLYNAGYTSLAHLANADPEVMVKKIEHLSRHQAKQI 970

  Fly  1020 VSAAKIILMKKLDHLEEETENL 1041
            |.:||:::.:|.:.|:||.:.|
 Frog   971 VFSAKMLVNEKAEALQEEVDEL 992

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mus301	NP_648178.1	BRR2	247..998	CDD:224125	330/758 (44%)
		DEXHc_POLQ-like	247..449	CDD:350784	111/201 (55%)
helq	XP_002939628.2	PRK02362	231..957	CDD:235032	332/766 (43%)
		DEXHc_POLQ-like	231..433	CDD:350784	111/201 (55%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	198	1.000	Domainoid score	I3036
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H14667
Inparanoid	1	1.050	653	1.000	Inparanoid score	I780
OMA	1	1.010	-	-		QHG56135
OrthoDB	1	1.010	-	-		D103838at33208
OrthoFinder	1	1.000	-	-		FOG0001214
OrthoInspector	1	1.000	-	-		oto105197
Panther	1	1.100	-	-	LDO	PTHR24031
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3974
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	11.080