Protein Alignment mus301 and polg

DIOPT Version :10

• Sequence 1: NP_648178.1
• Gene: mus301 / 38905
• FlyBaseID: FBgn0002899
• Length: 1051
• Species: Drosophila melanogaster
• Sequence 2: XP_001921130.3
• Gene: polg / 100150924
• ZFINID: ZDB-GENE-060303-1
• Length: 1206
• Species: Danio rerio
• Alignment Length: 901
• Identity: 154/901 - (17%)
• Similarity: 256/901 - (28%)
• Gaps: 381/901 - (42%)

  Fly     9 KKRSLDLSE--ESTSESHAKRQCTENLFWPEG-------EDDDSFFSNAHLEDLLDGRKEELFGT 64
            ||::...:|  |:.::|.|       :.|||.       |:.||           |.|:|.|...
Zfish   473 KKKAKQEAEATEAANDSEA-------IDWPEDPGPPLEEEEGDS-----------DPRRELLQRL 519

  Fly    65 QATTST---------------NKMTQSGSDDGLGLFADTSFPSAQSVPPNSASKPDEASAPTDKH 114
            :.|.|.               .|:....|:      |:...|.|..:.......|.......|..
Zfish   520 KETVSCLPKRRQHLPAHPSWYRKLCVKMSE------AEDWSPGASLISLQMRITPKLMGLTWDGF 578

  Fly   115 QIDLADEENADKLF--KKINLNDLSIAEMEDIFHGADDFSDPMVQNTQL------FLDAMTFKKP 171
            .:...|:.....|.  ::.|| |:|           :|..:|:.....:      :.:....::|
Zfish   579 PLHYTDQHGWGYLVPGRRDNL-DIS-----------EDNEEPVCPYRAIESVYKEYCEQKGKEQP 631

  Fly   172 KTPEKLLAPLKDDSMSFISKSVIEGLVQGTQYVTCEELKNQSLLDPVNWETQAFADFEKNNQDID 236
            |.|:   :|:.|:.|          |.....:.|.||:....:.|.....|.|
Zfish   632 KYPD---SPVSDELM----------LTDTAVWQTVEEVSRLEMFDDEALSTAA------------ 671

  Fly   237 KFPSKGEFYGLPDKVKKMILEHKGINSLYE-WQDEC-----------LNLPAIRQRKNLIYALPT 289
              |||        ::.|.      :||::: ...||           :|:|..     ..:.||.
Zfish   672 --PSK--------RITKK------VNSVFKSLNGECPYHHGNGPYNDVNIPGC-----WFFKLPH 715

  Fly   290 SGGKTLVAEILMLRELLCRERNVLFILPYVSIVQEKVSAMSPFAIDLDFIVEEYTAGKGKCPPQP 354
            ..|               .|.||                .|||:.|
Zfish   716 KDG---------------NENNV----------------GSPFSKD------------------- 730

  Fly   355 RRKRRSLFIASIEKGAVLMDSLIDVQRPHEIGLVVVDELHLIGEKGRGATLEAFLTKVMFLNANI 419
                   |::.:|.|.:                       ..|.:|..||....:.|::....|.
Zfish   731 -------FLSKMESGTL-----------------------QAGREGTNATRALEINKMISFWRNA 765

  Fly   420 QIVGMSATIGNLSEISSFLNADVYTRGFRPVELKEYIKCGPDLLEINSAGQTLEEIF----VPSR 480
            |           ..|||.:     ....|..||...::...|..|....|..|.::.    |..|
Zfish   766 Q-----------KRISSQM-----VVWLRRAELPRSVRLHQDYDEEGQYGAILPQVIPAGTVTRR 814

  Fly   481 SVEYNY---SEAVK--------------------RADPDH----LAGLISEC--APEHCCLVFCP 516
            :||..:   |.|.|                    .||.|.    :|.::.|.  |..|.|..|
Zfish   815 AVEPTWLTASNARKDRVGSELKAMVQVPPAYHLVGADVDSQELWIAAMLGEAHFAGMHGCTAF-- 877

  Fly   517 SRKNCENVALLLSRIVPKHKFFEHRRSEKLDLMDALDKMCGILSPVLAKTLPYGIAYHHSGLTTD 581
                             .....:.::|:..||........|| |...||...||..| .:|....
Zfish   878 -----------------GWMTLQGKKSQGTDLHSRTADAVGI-SREHAKVFNYGRIY-GAGQPFA 923

  Fly   582 ERKYIETAYRFGVVTVICCTSTLAAGVNLPAKRVIIRAPYVGQEFLTLCKYKQMVGRA---GRAG 643
            ||..::..:|.        :...|||                       |.:||....   .|..
Zfish   924 ERLLMQFNHRL--------SQQEAAG-----------------------KARQMYALTKGLRRYH 957

  Fly   644 LGEAGESILIAQSKDNLLVGQMLFSPMDKALSSLDQNEAVGLQSLILSVVGLNLAECRRDLNRLV 708
            |.|.||.:|           |.|...:::|     ::.::.||.|             |.::::.
Zfish   958 LSEEGEWLL-----------QKLNVNVERA-----EDGSISLQDL-------------RKISKVA 993

  Fly   709 NSTLLSVQAKSLEVAVNEIVLRILREMFKNKVLQLAEPQAKSKINSSDIITSQDVSQANRPAGDR 773
            ..:......|...:....:..........||:                    :.::|::|||
Zfish   994 TQSTTRGSKKKWNLTAGRVWTDGTESYMFNKL--------------------ESIAQSDRPA--- 1035

  Fly   774 RLLIGQSTPFKLTNIGRAAFKAGIDYKRANAIHKELKQAQQQLIL----TNYLHLL 825
                   ||.....|.||.        ..:|:.:|...::...::    .:||||:
Zfish  1036 -------TPVLNCRISRAL--------EPSAVQEEFITSRVNWVVQSSAVDYLHLM 1076

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mus301	NP_648178.1	DEXHc_POLQ-like	247..449	CDD:350784	30/213 (14%)
		BRR2	255..828	CDD:440817	104/623 (17%)
polg	XP_001921130.3	DNApol_Exo	90..383	CDD:465664
		DNA_pol_A	400..>442	CDD:470638
		DNA_pol_gammaA	741..1167	CDD:176478	85/471 (18%)