DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7504 and emb2411

DIOPT Version :9

Sequence 1:	NP_001137907.1	Gene:	CG7504 / 38904	FlyBaseID:	FBgn0035842	Length:	1676	Species:	Drosophila melanogaster
Sequence 2:	NP_001322072.1	Gene:	emb2411 / 837406	AraportID:	AT1G08840	Length:	1331	Species:	Arabidopsis thaliana

Alignment Length:	1583	Identity:	309/1583 - (19%)
Similarity:	519/1583 - (32%)	Gaps:	598/1583 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly   402 KQKGRRSKSKSPNDHVVRQADSTTPDLPAVRKLSVSSIDSVYENKQTKLNSKLKSCLKSP----- 461
            |....:|..:|..:|      |:.|....:::|.:..|    :|.|:..||...:.  .|
plant     8 KSSALKSNKQSSANH------SSQPSTFGIQQLFLRHI----QNSQSTSNSHTSTA--DPVDQQN 60

  Fly   462 -----TKTSVDNMENMTETKSCSNRQREQIVASRNEPTNICPQKIETNKTSTRKRF----VSTTS 517
                 :.|:|...:|...|   ||.:.::......:.|...| ||..|    .|||    :...|
plant    61 VNGLASDTAVLTPQNPLGT---SNEKPDESKDMDQQLTEASP-KISKN----LKRFSPGMLIKQS 117

  Fly   518 RDE--------LSTTSKEIKDAPKNNVEPPKKM-LRSRS---KSCYIDRPVELDEHITKNEVPLK 570
            :|:        :|..::.::.|.||   .||.| |...|   ||..| ||..|::.:.| :.|..
plant   118 QDDCGGEITWKISPVNERLRAAAKN---IPKMMDLTENSLGVKSSTI-RPCSLNKLVQK-QCPTS 177

  Fly   571 KKYESVDNSKEELIVTLEAPAMLTTPTKSKTQCVKKKATQTRGRRKTIHSRDEIRSLTAEAEENK 635
            .             :|.:....|::|:        |||::              |...|.....:
plant   178 G-------------ITSKVEQWLSSPS--------KKASK--------------RPAFATNRVME 207

  Fly   636 KISPAKQTNEEIPIPT----KSPLKRNARLLNRSKSCYMDRLVISETEDPA---------KKV-- 685
            :::|:.....|| :.|    .||.:....|     ||..::|..:.|...|         ||.
plant   208 RVNPSPDAEFEI-VNTSSSGNSPFQTPPSL-----SCPHNKLPCTVTCSGACGSMGAGQHKKALL 266

  Fly   686 -----IKDISPTKSDTTDNV--------------LNFVDVRQTRGPSVIEAPSLPKNRGKLR--- 728
                 ::|:......|||:|              .:.||.....||     .||||.:..:.
plant   267 ELLDQVEDVIAVDDKTTDDVGIVMPQARVKDDIISSVVDCAVDEGP-----VSLPKMQNSINPDS 326

  Fly   729 -------------GVSAEVKVKDKVLDRQRFIDYQAEMNAK---WKQ------KPKDK------- 764
                         |.|::.:...|||   |.:|....:...   |.:      .|.|.
plant   327 YFLVLEVSEKRGSGSSSKGQCPYKVL---RLLDEHTGVECALYLWDEWFYSTVSPGDSINVIGEF 388

  Fly   765 ----KKEDEKLKE--------------------CRREALKKLSEKPKENSHRSTTNKRKNPTSVP 805
                |.:.::...                    |.|..:  |.|:.:.|.|.:.       ..:.
plant   389 DGDGKCDVDRQNNFLIVHPDTLVAGTRVAASFGCPRRTV--LDERLRSNEHATV-------ALLG 444

  Fly   806 TVQNTNRGGFLTK---GVDGPAPKLAKTDNAKPPPKKPVPKQPPAIETFSQQLQAADKAVLHPQP 867
            |:|:......|::   .||| ..:.|.|                .||...:.|.|
plant   445 TLQHQVFQAGLSQESPSVDG-LQEYAST----------------VIEKSIESLYA---------- 482

  Fly   868 QCSRPVERKEAELARNQRTCNKVTFAEMELYHQKAEDSKKLQKKLRKVHFNDDVKVHCIERVKGA 932
             |.  |...:......:.....:.:.|...|.:.:|.|        ||.|...:
plant   483 -CG--VHEGDVRSTLFKAIPKMLNWIEHFRYSKDSEVS--------KVDFGSTI----------- 525

  Fly   933 SSKVQGRKECIKLRLSSYRERREWIRRENKPVNDIRQHSRSILKWANQWLKHGSVDA----VAEQ 993
                  .|:.:|:                ..|.||.:     :.||.::...|.:||    :.|.
plant   526 ------GKKAVKV----------------SEVIDIEE-----MSWAPKYGLKGMIDASVRVIVES 563

  Fly   994 DV------LMPI-------PPEFDSFKNYREI--FVPLMKLELLSTIERD--YKINNKNTFSVS- 1040
            |:      :||:       |....|.::..::  :..||....|..|:..  |.:.:..|..:|
plant   564 DMNTVNEKIMPLEFKSGKAPSGQSSIEHSAQVILYTLLMSERYLKHIDNGLLYYLQSDQTQGISV 628

  Fly  1041 -------------------LINVETQ------------------DMC--YRLVTRVNSKPFGKFV 1066
                               |:...||                  |:|  |......|::..|...
plant   629 QRSDLVGLIIRRNELANDILVASTTQQLPPMLRNPNICRNCRHLDVCTIYHKADGGNTESSGLGD 693

  Fly  1067 LYTLYCCGMLKETF------ANLLELK------------------------FVSGNVFDLT---- 1097
            ::..:...:....|      ..|::|:                        ::|..|.|:|
plant   694 VFDTHVSHLSTLHFNFLRHWDRLIDLEGREMQLLRKDIAHPHGSKGSHSASYLSSMVLDVTNGFQ 758

  Fly  1098 -----------FEILKQDISEE----------------------KLKNIKQLTARPVVDSLRVEL 1129
                       :..::|..||.                      ||:...::..|..|..|.|..
plant   759 HHNSHKETRFIYRFVRQKSSESRERVTSEDMIRTGNLATDDLDCKLRTGDRVILRTEVSHLTVAN 823

  Fly  1130 GALSAVHQLR-SSPLCRRILKP-TQTVNEVS--------LPKQPF-TFKGCHKLNEHQ---ENIV 1180
            |.::.:.:.. |..|.:|:..| ::..:|||        :.|..| |.....:.|..|   :|
plant   824 GIIADISRTHISVSLSKRLRLPWSEPSSEVSNLSHELWRIYKDEFMTSFSVMRFNLMQLFVQN-- 886

  Fly  1181 LHTYQRIIDDLQP---------------------------------------SLTLIQGPPGTGK 1206
            .|..:::|.||:|                                       ...||.|.|||||
plant   887 GHNIRKMIVDLEPPRFDNGSILSQDPAISYIWSEKSLNNDQRQAILKILTAKDYALILGMPGTGK 951

  Fly  1207 SRVISELCLQTLYGNAAKTL---DRKILICAHSNTAVDHIVGLLGSVLRVMNRDQFHLLRFGMHE 1268
            :..:.         :|.|.|   ...||:.:::|:|||::       |..:.......||.|..
plant   952 TSTMV---------HAVKALLIRGSSILLASYTNSAVDNL-------LIKLKAQGIEFLRIGRD- 999

  Fly  1269 KMSHYSRPFSLEAHFNKAKEQKLQRVSKENAEILKKQHNDLKDEIQQLKEKTNLTSTYLLQQLQQ 1333
                       ||...:.:|.....::..:.|       |:|.::.|:|.   :.||.|
plant  1000 -----------EAVHEEVRESCFSAMNMCSVE-------DIKKKLDQVKV---VASTCL------ 1037

  Fly  1334 KEKKLQLISNQLSPPLTQREEFEISHMCVTRANIICTTLSSCVKLANYVDFFDICIVDEATQCTE 1398
                     ...||.|..|.                               ||:||:|||.|...
plant  1038 ---------GINSPLLVNRR-------------------------------FDVCIIDEAGQIAL 1062

  Fly  1399 PWTLLPMRFGLTHMVLVGDMQQLPAVVLSKKAIDFGLSNSMFDRIQRSLQTQLDKPGSYHLMHTK 1463
            |.::.|:.|..| .|||||..|||.:|.|.:|.:.|:..|:|.|:..:              |.:
plant  1063 PVSIGPLLFAST-FVLVGDHYQLPPLVQSTEARENGMGISLFRRLSEA--------------HPQ 1112

  Fly  1464 LFK-LSTQYRMHPEICRWPNQYFYEDQLI--NAE--------CTARFASPLIPYCV--------I 1509
            ... |..||||...|....|...|.|:|.  :||        .|:...||.:...:        :
plant  1113 AISVLQNQYRMCRGIMELSNALIYGDRLCCGSAEVADATLVLSTSSSTSPWLKKVLEPTRTVVFV 1177

  Fly  1510 NLKYTCDSNGAQNKSISNNEEARFVAKLLTEM-DKHMPSKRFSYGLISPYQNQCYALSQVIPSHM 1573
            |.............:|:|..||..:|:::.|: :..:.||  ..|:|:||.:|...:...||:
plant  1178 NTDMLRAFEARDQNAINNPVEASIIAEIVEELVNNGVDSK--DIGIITPYNSQASLIQHAIPT-- 1238

  Fly  1574 NITP---QTVDSYQGLEKDVIIISNARTR------GCGFLTNYQRLNVALTRPRRCLVICGNFED 1629
              ||   .|:|.|||.:||.|::|..|:|      ....|.::.|:||||||.::.|::.|:...
plant  1239 --TPVEIHTIDKYQGRDKDCILVSFVRSREKPRSSASSLLGDWHRINVALTRAKKKLIMVGSQRT 1301

  Fly  1630 LKSVEMWRNLLDDARKRKVYFNL 1652
            |..|.:...||:..:::....||
plant  1302 LSRVPLLMLLLNKVKEQSGILNL 1324

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7504	NP_001137907.1	FHA	4..96	CDD:238017
		FHA	<10..101	CDD:224630
		AAA_11	1171..1428	CDD:289831	65/301 (22%)
		AAA_19	1194..1251	CDD:289986	17/59 (29%)
		YtxH	<1293..1347	CDD:295162	8/53 (15%)
		AAA_12	1435..1626	CDD:289832	57/219 (26%)
emb2411	NP_001322072.1	Dna2	356..559	CDD:370071	42/287 (15%)
		Cas4_I-A_I-B_I-C_I-D_II-B	506..676	CDD:382125	34/215 (16%)
		TIGR00376	801..1317	CDD:273041	147/622 (24%)
		DEXXQc_DNA2	922..1122	CDD:350799	66/298 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1112
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810