DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7504 and SDE3

DIOPT Version :9

Sequence 1:	NP_001137907.1	Gene:	CG7504 / 38904	FlyBaseID:	FBgn0035842	Length:	1676	Species:	Drosophila melanogaster
Sequence 2:	NP_172037.1	Gene:	SDE3 / 837047	AraportID:	AT1G05460	Length:	1002	Species:	Arabidopsis thaliana

Alignment Length:	934	Identity:	212/934 - (22%)
Similarity:	356/934 - (38%)	Gaps:	266/934 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   797 KRKNPTSVPTVQNTNRGGFLTKG-VDGPAPKLAKTDNAKP----------PPKK--PVPKQPPAI 848
            |::.|.|| ||..|:...|..|. :|.|.....|...:.|          ||.|  .:.::....
plant    52 KKEKPQSV-TVGETSFDSFTVKNTMDEPVDLWTKIYASNPEDSFTLSILKPPSKDSDLKERQCFY 115

  Fly   849 ETFS---QQLQAADKAV-----------LHPQPQC----SRPVERKEAELARNQRTCNKVTFAEM 895
            |||:   :.|:..|...           ||.....    |..|||....||.::.:.:..:
plant   116 ETFTLEDRMLEPGDTLTIWVSCKPKDIGLHTTVVTVDWGSDRVERVVFLLAEDKISSSLTS---- 176

  Fly   896 ELYHQKAEDSKKLQKKLRKVHFNDDVKVHCIERVKGA-SSKVQGRKECIKLRLSSY---RERREW 956
               ::....|::..||        |..|.  :.|||: .|||..|.  .:.||..|   :|.||.
plant   177 ---NRPYSRSRRAPKK--------DFAVD--DYVKGSRPSKVVERS--FRNRLPLYEIPKEIREM 226

  Fly   957 IRRENKPVNDIRQHSRSILKWANQWLKHGSVDAVAEQDVLMPIPPEFDSFKNYREIFVPLMKLEL 1021
            |  |||...|.          .|:.|                      :.:||...:..|:.:|.
plant   227 I--ENKEFPDD----------LNEGL----------------------TARNYANYYKTLLIMEE 257

  Fly  1022 LSTIERDYKINNKNTFSVS----LINVETQDMCYRLVTRVNSKPFGKFVL------------YTL 1070
            |. :|.|.:..:....|:.    .:::|...:..|..:.|:    |.|:.            |.
plant   258 LQ-LEEDMRAYDMENVSMKRRGIYLSLEVPGLAERRPSLVH----GDFIFVRHAYDDGTDHAYQ- 316

  Fly  1071 YCCGMLKETFANLLELKFVS--------GNVFDLTFEILKQDISEEKLKNIKQLTARPVVDSLRV 1127
               |.:....|:.:.:||.|        |:|:::.|...:  |:..:|  .:.:.|..::|...:
plant   317 ---GFVHRVEADEVHMKFASEFHQRHTAGSVYNVRFTYNR--INTRRL--YQAVDAAEMLDPNFL 374

  Fly  1128 ELGALSAVHQLRSSPLCRRILKPTQTVNEVSLPKQPFTFKGCHKLNEHQENIVLHTYQRIIDDLQ 1192
            .....|....:::.|.               :|..|       .||..|    :.:.:.::....
plant   375 FPSLHSGKRMIKTKPF---------------VPISP-------ALNAEQ----ICSIEMVLGCKG 413

  Fly  1193 PSLTLIQGPPGTGKSRVISELCLQ--TLYGNAAKTLDRKILICAHSNTAVDHIVGLLGSVLRVMN 1255
            ....:|.|||||||:..:.|..:|  |...||      ::|:||.||:|.|||:
plant   414 APPYVIHGPPGTGKTMTLVEAIVQLYTTQRNA------RVLVCAPSNSAADHIL----------- 461

  Fly  1256 RDQFHLLRFGMHEKMSHYSRPFSLEAHFNKAKEQKLQRVSKENAEILKKQHNDLKDEIQQLKEKT 1320
                        ||:      ..||.  .:.|:.::.|::...     :.:.::|.||.:.
plant   462 ------------EKL------LCLEG--VRIKDNEIFRLNAAT-----RSYEEIKPEIIRF---- 497

  Fly  1321 NLTSTYLLQQLQQKEKKLQLISNQLSPPLTQREEFEISHMCVTRANIICTTLSSCVKLANYVD-- 1383
                 ....:|..|           .|||.....:::         ::.|.:|:.:..|..|:
plant   498 -----CFFDELIFK-----------CPPLKALTRYKL---------VVSTYMSASLLNAEGVNRG 537

  Fly  1384 FFDICIVDEATQCTEPWTLLPM-RFGLTH--MVLVGDMQQLPAVVLSKKAIDFGLSNSMFDRIQR 1445
            .|...::|||.|.:||..::.: ...||.  :||.||.:||..|:.|:.|...||..|..:|:
plant   538 HFTHILLDEAGQASEPENMIAVSNLCLTETVVVLAGDPRQLGPVIYSRDAESLGLGKSYLERL-- 600

  Fly  1446 SLQTQLDKPGSYHLMHTKLFKLSTQYRMHPEICRWPNQYFYEDQLI--NAECTARFAS------- 1501
             .:......|..:.: |||.|   .||.||||...|::.||:.:|:  ..:..:..||
plant   601 -FECDYYCEGDENYV-TKLVK---NYRCHPEILDLPSKLFYDGELVASKEDTDSVLASLNFLPNK 660

  Fly  1502 --PLIPYCVINLKYTCDSNGAQNKSISNNEEARFVAKLLTEMDKHMPSKRFSYGLISPYQNQCYA 1564
              |::.|.:    ..||.....|.|..|..|...|.:.:..:..:...:....|:|:||:.|...
plant   661 EFPMVFYGI----QGCDEREGNNPSWFNRIEISKVIETIKRLTANDCVQEEDIGVITPYRQQVMK 721

  Fly  1565 LSQVIPSHMNITP---QTVDSYQGLEKDVIIISNART---------RGC-GFLTNYQRLNVALTR 1616
            :.:|: ..:::|.   .:|:.:||.||.|||||..|:         ..| |||:|.:|.|||:||
plant   722 IKEVL-DRLDMTEVKVGSVEQFQGQEKQVIIISTVRSTIKHNEFDRAYCLGFLSNPRRFNVAITR 785

  Fly  1617 PRRCLVICGNFEDLKSVEMWRNLL 1640
            ....|||.||...:.....|..||
plant   786 AISLLVIIGNPHIICKDMNWNKLL 809

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7504	NP_001137907.1	FHA	4..96	CDD:238017
		FHA	<10..101	CDD:224630
		AAA_11	1171..1428	CDD:289831	59/263 (22%)
		AAA_19	1194..1251	CDD:289986	22/58 (38%)
		YtxH	<1293..1347	CDD:295162	6/53 (11%)
		AAA_12	1435..1626	CDD:289832	61/214 (29%)
SDE3	NP_172037.1	DEXXQc_Helz-like	396..622	CDD:350796	70/307 (23%)
		AAA_12	592..796	CDD:372468	62/215 (29%)
		Ago_hook	830..957	CDD:371044
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1112
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000219
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810