DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7504 and LBA1

DIOPT Version :9

Sequence 1:	NP_001137907.1	Gene:	CG7504 / 38904	FlyBaseID:	FBgn0035842	Length:	1676	Species:	Drosophila melanogaster
Sequence 2:	NP_199512.2	Gene:	LBA1 / 834747	AraportID:	AT5G47010	Length:	1254	Species:	Arabidopsis thaliana

Alignment Length:	808	Identity:	217/808 - (26%)
Similarity:	344/808 - (42%)	Gaps:	214/808 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   935 KVQGRKECIKLRLSSYRERREWIRRENKPVNDIRQHSRSILKWANQWLKHGSVDAVAE------- 992
            ||...:|.::.|..|.::           :|.|.:      .|..      :.||..|
plant   263 KVPSEQEQLRARQISAQQ-----------INKIEE------LWKT------NPDATLEDLEKPGV 304

  Fly   993 QDVLMPIPPEFDSFKNYREIFVPLMKLELLSTIERDYKINNKNTFSVSLINVETQDMCYRLVTRV 1057
            .|...|:.|:::....|:.:|.||:||      |.||....|.:.|       .:::..|....:
plant   305 DDEPQPVQPKYEDAYQYQNVFAPLIKL------EADYDKMMKESQS-------KENLTVRWDIGL 356

  Fly  1058 NSKPFGKFVLYTLYCCGMLKETFANLLELKFVSGNVFDLTF-------------EILKQDISEEK 1109
            |.|....||        ..||.    .||:.|.|:...|.:             .::|....||.
plant   357 NKKRVAYFV--------FPKEE----NELRLVPGDELRLRYSGDAVHPSWQSVGHVIKLTAQEEV 409

  Fly  1110 LKNIKQLTARPV-------VDSL-------RVELGALS--AV----------HQLRSSPLCRRIL 1148
            ...::.....|:       ||.:       |:: ||:.  ||          |||....:..:::
plant   410 ALELRANQGVPIDVNHGFSVDFVWKSTSFDRMQ-GAMKNFAVDETSVSGYIYHQLLGHEVEAQMV 473

  Fly  1149 KPTQTVNEVSLPKQPFTFKGCHKLNEHQENIVLHTYQRIIDDLQPSLTLIQGPPGTGKSRVISEL 1213
            :.|       ||:: |...|..:||..|.|.|...       ||..::||||||||||:...:.:
plant   474 RNT-------LPRR-FGVPGLPELNASQVNAVKSV-------LQKPISLIQGPPGTGKTVTSAAI 523

  Fly  1214 CLQTLYGNAAKTLDRKILICAHSNTAVDHIVGLLGSVLRVMNRDQFHLLRFGMHEKMSHYSRPFS 1278
                :| :.||....::|:||.||.|||.:.                       ||:|
plant   524 ----VY-HMAKQGQGQVLVCAPSNVAVDQLA-----------------------EKIS------- 553

  Fly  1279 LEAHFNKAKEQKLQRVSKENAEILKK--QHNDLKDEIQQL--KEKTNLTSTYLLQQLQQKEKKLQ 1339
                   |...|:.|:..::.|.:..  ::..|..:::.|  .||:.|   :.||||:.::.:|.
plant   554 -------ATGLKVVRLCAKSREAVSSPVEYLTLHYQVRHLDTSEKSEL---HKLQQLKDEQGELS 608

  Fly  1340 LISNQLSPPLTQREEFEISHMCVTRANIICTTLSSCV-----KLANYVDFFDICIVDEATQCTEP 1399
            ....:....|.:..|.||:.    .|::||.|   ||     :|:|:  .|...::||:||.|||
plant   609 SSDEKKYKNLKRATEREITQ----SADVICCT---CVGAADLRLSNF--RFRQVLIDESTQATEP 664

  Fly  1400 WTLLPMRFGLTHMVLVGDMQQLPAVVLSKKAIDFGLSNSMFDRIQRSLQTQLDKPGSYHLMHTKL 1464
            ..|:|:..|:..:|||||..||..|::.|||...||:.|:|:|    |.|...||
plant   665 ECLIPLVLGVKQVVLVGDHCQLGPVIMCKKAARAGLAQSLFER----LVTLGIKP---------- 715

  Fly  1465 FKLSTQYRMHPEICRWPNQYFYEDQLINAECTARFASPLI--PYCVIN------LKYTCDSNGAQ 1521
            .:|..||||||.:..:|:..|||..|.|........:..|  |:.|.|      ::...:...|.
plant   716 IRLQVQYRMHPALSEFPSNSFYEGTLQNGVTIIERQTTGIDFPWPVPNRPMFFYVQLGQEEISAS 780

  Fly  1522 NKSISNNEEARFVAKLLTEMDKH--MPSKRFSYGLISPYQNQ-CYALSQVIPS-------HMNIT 1576
            ..|..|..||..|.||:|...|.  :||:   .|:|:||:.| .|.::.:..:       :..|.
plant   781 GTSYLNRTEAANVEKLVTAFLKSGVVPSQ---IGVITPYEGQRAYIVNYMARNGSLRQQLYKEIE 842

  Fly  1577 PQTVDSYQGLEKDVIIISNART---RGCGFLTNYQRLNVALTRPRRCLVICGNFEDLKSVEMWRN 1638
            ..:|||:||.|||.||:|..|:   :|.|||.:.:||||||||.|..:||.||.:.|....:|..
plant   843 VASVDSFQGREKDYIILSCVRSNEHQGIGFLNDPRRLNVALTRARYGIVILGNPKVLSKQPLWNG 907

  Fly  1639 LLDDARKRKVYFNLDRDDVNDLDRSLIK 1666
            ||...::.:.   |....:|:|.:|:::
plant   908 LLTHYKEHEC---LVEGPLNNLKQSMVQ 932

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7504	NP_001137907.1	FHA	4..96	CDD:238017
		FHA	<10..101	CDD:224630
		AAA_11	1171..1428	CDD:289831	76/265 (29%)
		AAA_19	1194..1251	CDD:289986	21/56 (38%)
		YtxH	<1293..1347	CDD:295162	12/57 (21%)
		AAA_12	1435..1626	CDD:289832	71/211 (34%)
LBA1	NP_199512.2	DNA2	164..929	CDD:224037	216/803 (27%)
		DEXXQc_UPF1	488..723	CDD:350797	90/309 (29%)
		Med15	<983..>1202	CDD:312941
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1112
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D62494at2759
OrthoFinder	1	1.000	-	-		FOG0000219
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.820