DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7504 and AT5G37140

DIOPT Version :9

Sequence 1:	NP_001137907.1	Gene:	CG7504 / 38904	FlyBaseID:	FBgn0035842	Length:	1676	Species:	Drosophila melanogaster
Sequence 2:	NP_198530.1	Gene:	AT5G37140 / 833686	AraportID:	AT5G37140	Length:	692	Species:	Arabidopsis thaliana

Alignment Length:	696	Identity:	175/696 - (25%)
Similarity:	277/696 - (39%)	Gaps:	224/696 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly  1133 SAVH-QLRSSPLCRRILKPTQTVNEVSLPKQPFTFKGCH------------KLNEHQENIVLHTY 1184
            :|:| :..:|.|.:.:|:......|     |.....|.|            |||..||..:|...
plant    27 NALHNEAANSTLIKSVLQENTLTTE-----QCVCESGAHGSDRVTNIIRSAKLNSSQEAAILSCL 86

  Fly  1185 QRIIDDLQPSLTLIQGPPGTGKSRVISEL--CLQTLYGNAAKTLDRKILICAHSNTAVDHIVGLL 1247
            :....:.:.|:.||.|||||||::.::.|  ||..|   :.||     ::||.:|||:..:...|
plant    87 KIRNCNHKHSVKLIWGPPGTGKTKTVATLLFCLLKL---SCKT-----VVCAPTNTAIVEVTSRL 143

  Fly  1248 GSVLR--------------VMNRDQFHLLRFGMHE------------------------------ 1268
            .|:.:              |::.:|   .|.|:.|
plant   144 LSLFKTSSSEHSTYGLGNIVLSGNQ---ARMGIKENDVLLDVFLDERIGILTSLFSPTSGWKQRL 205

  Fly  1269 ------------KMSHYSRPFSLEAHFNKAKEQKLQRVSKEN---------------AEILKKQH 1306
                        |..||       .|..|..|:..:...|:.               .|.:||..
plant   206 ESLIDFLENTEAKYEHY-------VHLLKEVERMSEEAEKKKKGADKKPKAIKILTFGEFVKKTF 263

  Fly  1307 NDLKDEIQQ----------------LKEKTNLTSTYLLQQLQQ--KE-------KK--------- 1337
            :...:|:::                ...|:.:|:...||:::.  ||       ||
plant   264 DGFSEELEKGMVDLWTHLPKSFITSENVKSMVTARKALQRVRYFLKENFSRDDFKKGSLKFDCFN 328

  Fly  1338 ------LQLISNQLSPPLTQREEFEISHM---------CVTRANIICTTLSSCVKLANYV--DFF 1385
                  ||::  :|.|     |.||:|.|         |:..|:||..|.|....: |.:  ...
plant   329 GVSAYCLQIL--RLLP-----ERFEVSDMLENNDTKTFCLQNADIIFCTASGAADM-NPIRTGSV 385

  Fly  1386 DICIVDEATQCTEPWTLLPMRF-GLTHMVLVGDMQQLPAVVLSKKAIDFGLSNSMFDRIQRSLQT 1449
            |:.:||||.|..|..::..::. ||.|.||:||..||||:|.::  ..||  .|:|:|:
plant   386 DLLVVDEAAQLKECESVAALQLSGLRHAVLIGDELQLPAMVHNE--AKFG--RSLFERL------ 440

  Fly  1450 QLDKPGSYHLMHTKLFKLSTQYRMHPEICRWPNQYFYEDQLINAECTAR------------FASP 1502
                   ..|.|.| ..|:.||||||.|.|:||:.||..::.:|.....            |.|
plant   441 -------VLLGHNK-HLLNVQYRMHPSISRFPNKEFYGGRIKDAANVQESIYQKRFLQGNMFGS- 496

  Fly  1503 LIPYCVINLKYTCDSNGAQNKSISNNEEARFVAKLLTEMDKHMPSKR--FSYGLISPYQNQCYAL 1565
               :..||:....:..| ...|..|..|...::::::.:.|....:|  .|.|::|||:.|..|:
plant   497 ---FSFINVGRGEEEFG-DGHSPKNMVEVAVISEIISNLFKVSSERRIKMSVGVVSPYKGQVRAI 557

  Fly  1566 SQ-------VIPSHMNITPQTVDSYQGLEKDVIIISNARTRG---CGFLTNYQRLNVALTRPRRC 1620
            .:       .:.....:..::||.:||.|:|:||||..|:.|   .|||.|.||.||||||.|.|
plant   558 QERTTNKYSSLSGLFTLNVRSVDGFQGGEEDIIIISTVRSNGNGKVGFLNNRQRANVALTRARHC 622

  Fly  1621 LVICGNFEDLK-SVEMWRNLLDDARKRKVYF------NLDRDDVND 1659
            |.:.||...|. |...|..|:.::|....::      || ||.:|:
plant   623 LWVIGNETTLALSGSSWAKLISESRTLGCFYDAADEKNL-RDAMNE 667

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7504	NP_001137907.1	FHA	4..96	CDD:238017
		FHA	<10..101	CDD:224630
		AAA_11	1171..1428	CDD:289831	88/381 (23%)
		AAA_19	1194..1251	CDD:289986	23/58 (40%)
		YtxH	<1293..1347	CDD:295162	16/108 (15%)
		AAA_12	1435..1626	CDD:289832	64/214 (30%)
AT5G37140	NP_198530.1	AAA_11	73..429	CDD:289831	88/381 (23%)
		AAA_19	95..155	CDD:289986	23/67 (34%)
		DNA2	<364..632	CDD:224037	93/291 (32%)
		AAA_12	432..628	CDD:289832	66/216 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	91	1.000	Domainoid score	I2617
eggNOG	1	0.900	-	-		E1_COG1112
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10887
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	5	4.870