DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7504 and AT5G37030

DIOPT Version :9

Sequence 1:	NP_001137907.1	Gene:	CG7504 / 38904	FlyBaseID:	FBgn0035842	Length:	1676	Species:	Drosophila melanogaster
Sequence 2:	NP_198519.1	Gene:	AT5G37030 / 833673	AraportID:	AT5G37030	Length:	638	Species:	Arabidopsis thaliana

Alignment Length:	753	Identity:	179/753 - (23%)
Similarity:	299/753 - (39%)	Gaps:	193/753 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   968 RQHSRSILKWANQWLKHGSVDAVAEQDV----LMPIPPEFDSFKNYREIFVP------------- 1015
            |....|:|.....|    |::.:..:|:    :..||.:|.|...|.:.|||
plant     3 RNEKTSLLDRIFSW----SMEDILNKDLYKQKIKTIPDKFSSVNEYLKCFVPHLLEETRTELSTS 63

  Fly  1016 --------LMKLELLSTI--ERDYKINNKNTFSVSL-----INVETQDMCYRLVTRVNSKPFGKF 1065
                    |.::..|.|:  |....::||..:.:|:     |..:.|..|..|:.....:|.|
plant    64 FKSLSKAHLFEISSLETMTKESSGSLSNKLFYDMSINDALSIREKYQPKCGDLIALTKERPRG-- 126

  Fly  1066 VLYTLYCCGMLKETFANLLELKFVSGNVFDLTFEILKQDISEEKLKNIKQLTARPVVDSLRVELG 1130
                                       |.||. .:|...||.:...||..:.:|.:....:..||
plant   127 ---------------------------VDDLN-PLLLGSISVDTYPNISVILSRLIFHDEKKSLG 163

  Fly  1131 ALSAVHQLRSSPLCRRILKPTQT-----VNEVSLPKQPFTFKGCHKLNEHQENIVLHTYQRIIDD 1190
            ...      :..|.:.:|:|...     |:..:..:.........|||..||..:|...:....:
plant   164 FAP------NFDLIQSVLQPNTAGMEPIVSSRTWGQNVLDIIRSSKLNSSQEAAILSCLETRDSN 222

  Fly  1191 LQPSLTLIQGPPGTGKSRVISELCLQTLYGNAAKTLDRKILICAHSNTAVDHIVGLLGSVLRVMN 1255
            .:.|:.||.||.   |::.::.|.|..|      .|..|.::||.:|||   ||.:...:|.:.|
plant   223 HKNSVKLIWGPL---KTKTVATLLLVLL------KLRCKTVVCAPTNTA---IVEVTSRLLALSN 275

  Fly  1256 RDQFHLLRFGMHEKMSHYSRPFSLEAHFNKAKEQKLQRVSKENAEILKKQHNDLKDEIQQLKEKT 1320
            :...| ..:|:              .:...|..||..|:  ::.:.|:...  |...|.:|: |.
plant   276 KYSEH-ATYGL--------------GNIFLAGNQKRMRI--KDTDYLRNVF--LDHRISKLR-KL 320

  Fly  1321 NLTSTYLLQQLQQKEKKLQLISNQLSPPLTQREEFEISHMCVTRANIICTTLSSCVKLANYVDFF 1385
            .|::....|.|   |..:.|:.|      |:                        .|..|    .
plant   321 FLSTCGWKQSL---ESIIDLLEN------TE------------------------TKTGN----I 348

  Fly  1386 DICIVDEATQCTEPWTLLPMRF-GLTHMVLVGDMQQLPAVVLSKKAIDFGLSNSMFDRIQRSLQT 1449
            ::.:||||.|..|..::..::. ||.|.:|:||..||||:|.:.:........|:|:|:.
plant   349 EVLVVDEAAQLKECESVAALQLPGLRHAILIGDEFQLPAMVHNDQCEKAKFGRSLFERLV----- 408

  Fly  1450 QLDKPGSYHLMHTKLFKLSTQYRMHPEICRWPNQYFYEDQLINAECTAR------------FASP 1502
                     |:..|...|..||||||.|.|:|.:.||..::.:|.....            |.|
plant   409 ---------LLGHKKHLLDVQYRMHPSISRFPYKEFYGGRIKDAANVQESIYQKRFLQGNMFGS- 463

  Fly  1503 LIPYCVINLKYTCDSNGAQNKSISNNEEARFVAKLLTEMDKHMPSK--RFSYGLISPYQNQCYAL 1565
               :..||:....:..| ...|..|..|...|:::::.:.|....:  :.|.|:|:||:.|..|:
plant   464 ---FSFINVGRGKEEFG-DGDSPKNMVEVAVVSEIISNLFKVSRERKMKMSVGVITPYKGQVRAI 524

  Fly  1566 SQVIPSH--------MNITPQTVDSYQGLEKDVIIISNARTRG---CGFLTNYQRLNVALTRPRR 1619
            .:.|...        ..:..::||.:||.|:|:||||..|:..   .|||:|.||.||||||.|.
plant   525 QERIRDKYSSLSGELFTVNVRSVDGFQGGEEDIIIISTVRSNSNGKVGFLSNRQRANVALTRARH 589

  Fly  1620 CLVICGNFEDL-KSVEMWRNLLDDARKRKVYFNLDRDD 1656
            ||.:.||...| :|..:|.||:.|:::||.:::. :||
plant   590 CLWVIGNESTLARSGSIWANLISDSKRRKCFYDA-KDD 626

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7504	NP_001137907.1	FHA	4..96	CDD:238017
		FHA	<10..101	CDD:224630
		AAA_11	1171..1428	CDD:289831	63/257 (25%)
		AAA_19	1194..1251	CDD:289986	18/56 (32%)
		YtxH	<1293..1347	CDD:295162	12/53 (23%)
		AAA_12	1435..1626	CDD:289832	62/215 (29%)
AT5G37030	NP_198519.1	AAA_11	203..390	CDD:289831	62/255 (24%)
		DNA2	<344..622	CDD:224037	91/300 (30%)
		AAA_12	399..596	CDD:289832	62/215 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1112
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D62494at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10887
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	5	4.880