DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7504 and AT4G30100

DIOPT Version :9

Sequence 1:	NP_001137907.1	Gene:	CG7504 / 38904	FlyBaseID:	FBgn0035842	Length:	1676	Species:	Drosophila melanogaster
Sequence 2:	NP_001320087.1	Gene:	AT4G30100 / 829133	AraportID:	AT4G30100	Length:	1311	Species:	Arabidopsis thaliana

Alignment Length:	1342	Identity:	313/1342 - (23%)
Similarity:	506/1342 - (37%)	Gaps:	396/1342 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   565 NEVPLKKKYESVD--NSKEELIVTL-----EAPAMLTTPTKSKTQC----VKKKATQTRGRRKTI 618
            ||:|.:.. :.:|  |..::..||:     .:.|:|.||:.|:...    |...|:...|.:..:
plant    12 NELPTEDD-DGIDNVNFNQQPQVTIPSSNPSSSALLATPSSSQDNVNNNRVFSHASTVSGFQPFV 75

  Fly   619 HSRDEIRSLTAEAEENK----KISPAKQTNEEIPIPTKSPLKRNARLLNRSKSCYMDRLVISETE 679
              |......|..|.|.|    .:..||.|:.::|....:|.:.....              :|:|
plant    76 --RPVAAQHTDVAVERKVDEGSLEEAKVTSLKVPNDVGAPEREEGEW--------------TESE 124

  Fly   680 DPAKKVIKDISP----TKSD--------TTDNVLNFVDVRQTRGPSVIEAPSL--PKNRG----- 725
            .||...:...|.    |:.|        .:|:.|...:|......|..::.|:  |:.:|
plant   125 VPANDNVHSSSDYSTVTEKDNGTLGLDINSDSALQKKNVNHISESSGKDSGSIDSPQEQGLTVRP 189

  Fly   726 -KLRGVSAEVKVKDKVLDRQRFIDYQAEMNAKWKQKPKDKKKEDEKLKECRREALKKLSEKPKEN 789
             :.:||.|...:|......:|.:|:|       |:....||:.       |:.....|.:..:..
plant   190 RETKGVEASHAIKCANTTVKRKMDHQ-------KETMLGKKRH-------RQTMFLNLDDVRQAG 240

  Fly   790 SHRSTTNKRKN---PTSVPTVQNTNRGGFLTKGVDGPAPKLAKTDNAKP--------PPKKPVPK 843
            ..::||.:|:|   |....||:. :|.|..|....|..|......:.||        .|:...||
plant   241 PIKTTTPRRQNFPQPVVTRTVRE-SRAGPPTAEQAGGVPGHVVYRDQKPIDIPNGGIHPETSEPK 304

  Fly   844 ---------------------QPPAIETFSQQL--QAADKAVLHPQPQCSRPVERKEAELARNQR 885
                                 ..|:.|..|..:  |.:.|     ||..||  :.|....:..|.
plant   305 LESNGESQSGSAGKTRRMNGEAGPSAEATSTSVSRQGSWK-----QPINSR--QLKSGHSSNRQV 362

  Fly   886 TCNKVTFAEMELYHQKAEDSKK------------LQKKLRKV------HFNDDVKVHCI-ERVKG 931
            .....|.|:.:..::|....||            :::.||:|      |..:|..:..: ||.:.
plant   363 PLCSQTSADSKFGNKKFTSFKKQATNSTQYQDTSVERLLREVTNEKFWHHPEDTDLQSVPERFES 427

  Fly   932 ASSKVQG-----RKECIKLRLSSYRE----------RREWIRRENKPVNDIRQHSRSILKWANQW 981
            ....|:.     .:||.....|::.|          |.::|.|..:...|:..:|.:..|||
plant   428 MDEYVRVFEPLLFEECRAQLYSTWEELAEANSYMKVRIKFIERRERGWYDVILNSVNECKWA--- 489

  Fly   982 LKHGSVDAVAEQDVLMPIPPEFDSFKNYREIFVPLMKLELLSTIERDYKINNKNTFSVSLINVET 1046
            .|.|.|..::.     |:|   :|...:.::.      .:..|:.|             .|.|:|
plant   490 FKEGDVAVLSN-----PVP---ESEGEHDDVG------RVAGTVRR-------------YIPVDT 527

  Fly  1047 QDMCYRLVTRVNSKPFGKFVLYTLYCCGMLKETFANLLELKFVSGNVFDLTFEILKQDISEE-KL 1110
            :|            |.|..                    |.|..|:.:|...:|....|..: |.
plant   528 RD------------PHGAI--------------------LHFYVGDAYDSGSKIDDNHILRKLKP 560

  Fly  1111 KNIKQLTARPVVDSLRVELGALSAVHQLRSSPLCRRILKP-----------TQTVNEVSLPKQPF 1164
            |.|..||....:.:.:.|..||.|..|| :..:...||||           |.||.:...|
plant   561 KEIWHLTVLGSIATTQREYVALHAFSQL-NPQMQNAILKPSPEQFPNYGEQTPTVPDCFTP---- 620

  Fly  1165 TFKG-CHK-LNEHQENIV----LHT-------YQRIIDDLQPSLTLIQGPPGTGKSRV------- 1209
            :|.| .|: .|..|...:    :||       .:|  .|..| .||:||||||||:..
plant   621 SFAGHLHRSFNAPQLAAIHWAAMHTAAGTSSGVKR--QDPWP-FTLVQGPPGTGKTHTVWGMLNV 682

  Fly  1210 -------------------------------------ISELCLQTLYGNAAKTLDR-----KILI 1232
                                                 |.|: ||.:..|..:||.:     ::|:
plant   683 IHLVQYQQYYTSLLKKLAPESYKQVNESSSDNIVSGSIDEV-LQNMDQNLFRTLPKLCAKPRMLV 746

  Fly  1233 CAHSNTAVDHIV------GLLGSVLRVMNRDQFHLLRFGMHEKMSHYSRPFSLEAHFNKAKEQKL 1291
            ||.||.|.|.::      |.:...:||...|   :.|.|: :..:..::..|:|...:..
plant   747 CAPSNAATDELLSRVLDRGFIDGEMRVYRPD---VARVGV-DTQTKAAQAVSVERRSDLL----- 802

  Fly  1292 QRVSKENAEILKKQHN------DLKDEIQQLKEKTNLTST---------------YLLQQLQQKE 1335
              ::|...|||...||      .|..:|..||.:  ||:.               .|:.:.|.::
plant   803 --LAKSREEILGHIHNLRVRDAQLSQDIAGLKRE--LTAAAFANRSQGSVGVDPDVLMVRDQTRD 863

  Fly  1336 KKLQLISNQLSPPLTQREE--FEISHMCV-------------------------TRANIICTTLS 1373
            ..||    :||..:..|::  .|:|.:.:                         ..|.|:.||:|
plant   864 AMLQ----RLSAVVEARDKDLVEMSRLLIVEGKFRAGTSFNLEEARASLEASFANEAEIVFTTVS 924

  Fly  1374 SCVK--LANYVDFFDICIVDEATQCTEPWTLLPMRFGLTHMVLVGDMQQLPAVVLSKKAIDFGLS 1436
            |..:  .:.....||:.::|||.|.:|...|.|:..|....|||||.|||||.|:||.|.....|
plant   925 SSGRKLFSRLTHGFDMVVIDEAAQASEVGVLPPLALGAARCVLVGDPQQLPATVISKAAGTLLYS 989

  Fly  1437 NSMFDRIQRSLQTQLDKPGSYHLMHTKLFKLSTQYRMHPEICRWPNQYFYEDQLINAECTARFA- 1500
            .|:|:|.|              |.......|:.||||||:|..:|::|||:.:|.::|..:...
plant   990 RSLFERFQ--------------LAGCPTLLLTVQYRMHPQIRDFPSRYFYQGRLTDSESVSTAPD 1040

  Fly  1501 ------SPLIPYCVINLKYTCDSNGAQNKSISNNEEARFVAKLLTEMDKHMPS---KRFSYGLIS 1556
                  |.|.||...::.:..:|:...:.|..|.:||||...:...:.:.:.|   .:.|.|:|:
plant  1041 EIYYKDSVLKPYLFFDISHGRESHRGGSVSYENIDEARFCVGVYLHLQRTLKSLGGGKVSVGVIT 1105

  Fly  1557 PY--QNQCY------ALSQVIPSHMNITPQTVDSYQGLEKDVIIIS--NARTRGCGFLTNYQRLN 1611
            ||  |.:|.      ||||  .....|...|||::||.|:||||:|  .|...|.||:.:.:|:|
plant  1106 PYKLQLKCLKIEFGNALSQ--DELQEIYINTVDAFQGQERDVIIMSCVRASNHGVGFVADIRRMN 1168

  Fly  1612 VALTRPRRCLVICGNFEDLKSVEMWRNLLDDARKRKVYFNLD 1653
            |||||.:|.|.:.||...|...|.|..|:.||:.|..:..::
plant  1169 VALTRAKRALWVMGNASALMKCEDWAALITDAKARNCFMEME 1210

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7504	NP_001137907.1	FHA	4..96	CDD:238017
		FHA	<10..101	CDD:224630
		AAA_11	1171..1428	CDD:289831	87/373 (23%)
		AAA_19	1194..1251	CDD:289986	25/111 (23%)
		YtxH	<1293..1347	CDD:295162	17/74 (23%)
		AAA_12	1435..1626	CDD:289832	68/210 (32%)
AT4G30100	NP_001320087.1	DEXXQc_SETX	630..1011	CDD:350800	98/415 (24%)
AT4G30100	NP_001320087.1	AAA_12	988..1185	CDD:404073	70/212 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1112
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D62494at2759
OrthoFinder	1	1.000	-	-		FOG0000219
OrthoInspector	1	1.000	-	-		otm3309
orthoMCL	1	0.900	-	-		OOG6_101455
Panther	1	1.100	-	-	O	PTHR10887
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	8	7.780