DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7504 and MAA3

DIOPT Version :9

Sequence 1:	NP_001137907.1	Gene:	CG7504 / 38904	FlyBaseID:	FBgn0035842	Length:	1676	Species:	Drosophila melanogaster
Sequence 2:	NP_001329005.1	Gene:	MAA3 / 827233	AraportID:	AT4G15570	Length:	818	Species:	Arabidopsis thaliana

Alignment Length:	788	Identity:	201/788 - (25%)
Similarity:	310/788 - (39%)	Gaps:	229/788 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly  1008 NYREIFVPLMKLELLSTIERDYKINNKNTFSVSLINVETQDMCYRLVTRVNSKPFGKFVLYTL-- 1070
            :|.|.|.||:..|:.:.|     :.||:....|:..:       |||...|......|:|.|.
plant    59 DYFETFEPLLFEEVKAQI-----LQNKDGEEASVCKM-------RLVMECNEGEGFHFLLVTYEH 111

  Fly  1071 ----YCCGMLKETFANLLELKFVSGNVFDLTFEILKQDISEEKLKNIKQLTARPVVD------SL 1125
                |    |.:....||..:.|.||.|..::.....:..:..|..::...|..:|.      |.
plant   112 EEDEY----LAQNDLLLLSKEEVKGNSFPSSYGFAVVEHRQNNLLRLRMYLAEDIVQITKNTKSS 172

  Fly  1126 RVE--LGALSAVHQL---RSSPLCRR-----------ILKPTQTVNEV-SLPKQPFTFKGCHK-- 1171
            |.:  :.|||.:..|   .:||:.:|           |::....:..| |||.:...|....|
plant   173 RTKSFIQALSNMRSLITSSASPIDKRVFSLKLCGLSTIIREYIALRSVSSLPFKDLIFTAAEKSC 237

  Fly  1172 ------------LNE-HQENIVLHTYQRIIDDL---QPSLTLIQGPPGTGKSRVI---------- 1210
                        ||| ..||  |:..|:...|:   :.|..||||||||||::.|
plant   238 GFGDEAWKISGPLNEFFNEN--LNKSQKEAIDVGLSRKSFVLIQGPPGTGKTQTILSILGAIMHA 300

  Fly  1211 -----------------SELCLQTLYG-------------------------------------- 1220
                             .::.:|..|.
plant   301 TPARVQSKGTDHEVKRGIQMTIQEKYNHWGRASPWILGVNPRDAIMPEDGDDGFFPTSGNELKPE 365

  Fly  1221 --NAAKTLDRKILICAHSNTAVDHIV-GLLGSVLRVMNRDQF--HLLRFGMHEKMSHYSRPFSLE 1280
              ||::....::|:||.||:|:|.|| .||.|.||..|...:  .::|.|             |:
plant   366 VVNASRKYRLRVLVCAPSNSALDEIVLRLLSSGLRDENAQTYTPKIVRIG-------------LK 417

  Fly  1281 AHFNKAKEQKLQRVSKENAEILKKQHNDLKDEIQQLKEKTNLTS--TYLLQQLQQKEKKLQLISN 1343
            ||.:.|.      ||.::  ::.::.....|:.:|....|::.|  |.:|::
plant   418 AHHSVAS------VSLDH--LVAQKRGSAIDKPKQGTTGTDIDSIRTAILEE------------- 461

  Fly  1344 QLSPPLTQREEFEISHMCVTRANIICTTL--SSCVKLANYVDFFDICIVDEATQCTEPWTLLPMR 1406
                                 |.|:..||  |....||.....||:.|:|||.|..||.||:|:.
plant   462 ---------------------AAIVFATLSFSGSALLAKSNRGFDVVIIDEAAQAVEPATLIPLA 505

  Fly  1407 FGLTHMVLVGDMQQLPAVVLSKKAIDFGLSNSMFDRIQRSLQTQLDKPGSYHLMHTKLFKLSTQY 1471
            .....:.||||.:||||.|:|..|.|.|...|||:|:|::         .|.:   |:.|  |||
plant   506 TRCKQVFLVGDPKQLPATVISTVAQDSGYGTSMFERLQKA---------GYPV---KMLK--TQY 556

  Fly  1472 RMHPEICRWPNQYFYEDQL-----INAECTARFASPLI--PYCVINLKYTCDSN--GAQNKSISN 1527
            ||||||..:|::.|||..|     |.|:.|..:.....  |:|..::....:|.  ||....: |
plant   557 RMHPEIRSFPSKQFYEGALEDGSDIEAQTTRDWHKYRCFGPFCFFDIHEGKESQHPGATGSRV-N 620

  Fly  1528 NEEARFVAKLLTEMDKHMPSKRFS--YGLISPYQNQCYALSQVIPSHMN------ITPQTVDSYQ 1584
            .:|..||..:...:....|..:.|  ..:||||..|.............      :...|||.:|
plant   621 LDEVEFVLLIYHRLVTMYPELKSSSQLAIISPYNYQVKTFKDRFKEMFGTEAEKVVDINTVDGFQ 685

  Fly  1585 GLEKDVIIISNARTR---GCGFLTNYQRLNVALTRPRRCLVICGNFEDLKSVEMWRNLLDDARKR 1646
            |.||||.|.|..|..   ..|||:|.:|:||.:||.:..:::.|:...|||..:|:||::.|.:|
plant   686 GREKDVAIFSCVRANENGQIGFLSNSRRMNVGITRAKSSVLVVGSAATLKSDPLWKNLIESAEQR 750

  Fly  1647 KVYFNLDR 1654
            ...|.:.:
plant   751 NRLFKVSK 758

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7504	NP_001137907.1	FHA	4..96	CDD:238017
		FHA	<10..101	CDD:224630
		AAA_11	1171..1428	CDD:289831	82/348 (24%)
		AAA_19	1194..1251	CDD:289986	28/124 (23%)
		YtxH	<1293..1347	CDD:295162	8/55 (15%)
		AAA_12	1435..1626	CDD:289832	62/210 (30%)
MAA3	NP_001329005.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1112
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D62494at2759
OrthoFinder	1	1.000	-	-		FOG0000219
OrthoInspector	1	1.000	-	-		otm3309
orthoMCL	1	0.900	-	-		OOG6_101455
Panther	1	1.100	-	-	LDO	PTHR10887
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	8	7.780