DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7504 and 4933416I08Rik

DIOPT Version :9

Sequence 1:	NP_001137907.1	Gene:	CG7504 / 38904	FlyBaseID:	FBgn0035842	Length:	1676	Species:	Drosophila melanogaster
Sequence 2:	NP_081976.1	Gene:	4933416I08Rik / 71159	MGIID:	1918409	Length:	280	Species:	Mus musculus

Alignment Length:	246	Identity:	52/246 - (21%)
Similarity:	88/246 - (35%)	Gaps:	60/246 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   260 PSAER-EVDDEEEYDESFAMSQAVIREMKAEMHVSDGE-----EDFLLTNG---MGNLP------ 309
            ||.|| ::..|.|.:....|...          .|.|.     ||.:..:.   :|::|
Mouse    40 PSVERGQIHQEGELNTKIVMGTV----------TSFGNDYGWIEDCIFFSSDAIIGSIPLRTGDK 94

  Fly   310 -----EGSP-SNQAYDDIVYVSDSD--DDELYDKVADWSKLLSQKVVPDVIEMSQTY-------- 358
                 |..| |::.....|.||..:  ..:...||.|.|..:|| |..:.|.:...|
Mouse    95 VLAFVEEDPLSHELKATEVCVSSEEGVSKDADSKVKDLSVCVSQ-VKKNFIYIGDEYYFYLDSIS 158

  Fly   359 -------PLENEHKDSDSDLDIGAKKPKRTLRISSSSDEDSADEVIVHQT-KQKGRRSKSKSPND 415
                   |.|.:..|.:..::.|:  ||.|:....::.....:||.|... |:||..      |.
Mouse   159 KAILGFTPREGDWLDIEYSVEQGS--PKITVHSVKATQRRQLEEVCVTSIHKRKGML------NH 215

  Fly   416 HVVRQADSTTPDLPAVRKLSVSSIDSVYENKQTKLNSKLKSCLKSPTKTSV 466
            .:....||.  :||......:..:.:|...:.|:.|.|.::...:|...:|
Mouse   216 TIFFTLDSL--NLPLGYTPILGHMVNVVIIQSTQQNYKWRAISMTPISPTV 264

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7504	NP_001137907.1	FHA	4..96	CDD:238017
		FHA	<10..101	CDD:224630
		AAA_11	1171..1428	CDD:289831
		AAA_19	1194..1251	CDD:289986
		YtxH	<1293..1347	CDD:295162
		AAA_12	1435..1626	CDD:289832
4933416I08Rik	NP_081976.1	S1-like	60..>103	CDD:291136	7/52 (13%)
4933416I08Rik	NP_081976.1	S1-like	203..254	CDD:291136	13/58 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1112
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900