DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7504 and helz2c

DIOPT Version :9

Sequence 1:	NP_001137907.1	Gene:	CG7504 / 38904	FlyBaseID:	FBgn0035842	Length:	1676	Species:	Drosophila melanogaster
Sequence 2:	NP_001018332.1	Gene:	helz2c / 552926	ZFINID:	ZDB-GENE-050508-3	Length:	231	Species:	Danio rerio

Alignment Length:	166	Identity:	43/166 - (25%)
Similarity:	67/166 - (40%)	Gaps:	44/166 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly  1534 VAKLLTEMDKHMPSKRFSYGLISPYQNQCYALSQVIPSH--MNITPQTVDSYQGLEKDVIIISNA 1596
            ||.||.:.....|.   ...:::||..|...:...:...  .|:|..||...||.|...:|:|..
Zfish    60 VADLLIKQSGVSPE---HIAILTPYNAQVSEIKMTLEKKNVRNVTVCTVMKSQGSEWPYVIVSTV 121

  Fly  1597 RT-------------------RGCGFLTNYQRLNVALTRPRRCLVICGNFEDLKSVEMWRNLLD- 1641
            |:                   :..||:|:..::|||:||.:..|.|.||.:.|:..|:|..|||
Zfish   122 RSCSTSDIQAYRVRPHKAWLGKRLGFVTDANQVNVAITRAQDGLCILGNSDLLRCCELWDRLLDH 186

  Fly  1642 ------------DAR-KRK------VYFNLDRDDVN 1658
                        |.| |.|      :|....::|:|
Zfish   187 YYRKSCVVNPASDIRVKAKASEGLAIYTGNQKEDIN 222

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7504	NP_001137907.1	FHA	4..96	CDD:238017
		FHA	<10..101	CDD:224630
		AAA_11	1171..1428	CDD:289831
		AAA_19	1194..1251	CDD:289986
		YtxH	<1293..1347	CDD:295162
		AAA_12	1435..1626	CDD:289832	28/112 (25%)
helz2c	NP_001018332.1	UvrD_C_2	<58..172	CDD:304668	30/114 (26%)
helz2c	NP_001018332.1	DNA2	<60..194	CDD:224037	36/136 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170581696
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840