Protein Alignment CG7504 and hrr1

DIOPT Version :9

• Sequence 1: NP_001137907.1
• Gene: CG7504 / 38904
• FlyBaseID: FBgn0035842
• Length: 1676
• Species: Drosophila melanogaster
• Sequence 2: NP_588411.2
• Gene: hrr1 / 2539248
• PomBaseID: SPCC1739.03
• Length: 999
• Species: Schizosaccharomyces pombe
• Alignment Length: 1268
• Identity: 269/1268 - (21%)
• Similarity: 444/1268 - (35%)
• Gaps: 494/1268 - (38%)

  Fly   621 RDEIRSL-TAEAEE--NKKISPAKQTNEEIPIP-TKSPLKRNARLLN-----RSKSCYMDRLVIS 676
            :|||..| |.:|.|  ||.   .:...:|||.| |.|.:||:....|     .:.:.:.:::..|
pombe     5 QDEIWKLSTLDAWEMVNKN---TEVVFDEIPEPETLSEMKRHPLYSNIFNADNNTTSFTEQIETS 66

  Fly   677 ETEDPAKKVIKDISPTKSDTTDNVLNFVDVRQTRGPSVIEAPSLPKNRGKLRGVSAEVKVKDKVL 741
            ||               |.|.|:..|.||            .:|.:|               |.:
pombe    67 ET---------------SKTQDSEGNKVD------------KNLKEN---------------KSI 89

  Fly   742 DRQRFIDYQAEMNAKWKQKPKDKKKEDEKLKECRREALKKLSEKPKENSHR--STTNKRKNPTSV 804
            .|:|.||                  .|.:|...:|..:.....:..||.|.  |.|:..:...|:
pombe    90 RRKRSID------------------NDYELSNVKRNDITSGKNREFENEHHPASDTSSWRELPSI 136

  Fly   805 PTVQNTNRGGFLTKGVDGPAPKLAKTDNAKPPPKKPVPKQPPAIETFSQQLQAADKAVLHPQPQC 869
            ||::.     ..:|.|:.|:..:.                 ...::|...|.      :|.:...
pombe   137 PTLEE-----LTSKSVELPSNNIY-----------------GGYKSFEDYLS------IHYRLLR 173

  Fly   870 SRPVERKEAELARNQRTCNKVTFAEMELYHQKAEDSKKLQKKLRKVHFNDDVKVHCIERVKG--A 932
            ...|......:.|.:...|.:|.:.:.:|                    |.|      |:.|  .
pombe   174 EDAVSPLRESVLRYKVNPNYITGSSLAVY--------------------DHV------RIDGYTI 212

  Fly   933 SSKVQGRKECIKLRLS-SYRERREWIRRENKPVNDIRQHSRSILKWA-NQWLKHGSVDAVAEQDV 995
            ||.|      |..:|| |.|.:::                   :||| ::.|..||:..::..|
pombe   213 SSSV------IAAKLSFSVRAKKK-------------------IKWATSRRLISGSLVLLSNDD- 251

  Fly   996 LMPIPPEFDSFKNYREIFVPLMKLELLSTIERDYKINNKNTFSVSLINVETQDMCYRLVTRVNSK 1060
                   |.:|:.......||..|             ||:...   |:|:.:|:      .::..
pombe   252 -------FQTFRIGTVCARPLSGL-------------NKHPHE---IDVKFEDI------SISLD 287

  Fly  1061 PFGKFVLYTLYCCGMLKETFANLL-ELKFVSGNVFDLTFEILKQDISEEKLKNIK--QLTARPVV 1122
            |..::|:  :.......|.:.::| .|:.:|.:.|.:          ::.|.:.|  |.||:.:.
pombe   288 PREEYVM--IEATSGYWEAYKHVLRSLQRLSASTFPM----------KDYLVHCKSNQETAKHIQ 340

  Fly  1123 DSLRVELGALSAVHQLRSSPLCRRILK--PTQTVNEVSLPKQPFTFKGCHKLNEHQENIVLHTYQ 1185
            ::.|:.:.:               |||  ..:.||.:    :||. .|.:.|:..|    |..||
pombe   341 NNPRIRINS---------------ILKNNSQKIVNAL----EPFG-PGEYILDSSQ----LKAYQ 381

  Fly  1186 RIIDDLQPSLTLIQGPPGTGKSRVISELCLQTLYGNAAKTLDRKILICAHSNTAVDHI-VGLL-- 1247
            .:   |...|::||||||||||.|..: .::||..|....: ..||:...:|.|||.| :.||
pombe   382 SM---LTKRLSIIQGPPGTGKSFVTLK-AIETLLENTHSHV-LPILVACQTNHAVDQILIRLLHQ 441

  Fly  1248 -GSVLRVMNRDQF-HLLRFGMHEKMSHYSRPFSLEAHFNKAKEQKLQRVSKENAEILKKQHN-DL 1309
             .||:|:.:|.:. .:....:.:|..|....|  :|.:|:.:.:| ||:.|:...|:   || :|
pombe   442 GASVMRLGSRTKDPEIAAVTIFQKAKHTKHSF--KAAYNEIRHKK-QRLIKQITNIM---HNFNL 500

  Fly  1310 K---------------DEIQQLK-------------EKT--NLTSTYL----------------- 1327
            :               .:::.|:             |||  .|.|.:|
pombe   501 EFVTLSYLHSKGIITTSQLESLRNNTEWISSVAENGEKTEEELISIWLGDAKVELITPSEITDGF 565

  Fly  1328 LQQLQQKEKKLQLISNQ-----------------------LSPPLTQREEFEISHMCV------- 1362
            .::||...:||:.|..:                       |...||...|.||..:..
pombe   566 EEELQIDPEKLEEIQKEAEDSGALMEEELRGKFINLRCKYLFSKLTTLHEKEIDTLLTIPNIWDI 630

  Fly  1363 ---TRANIICTTLSSCVKLA--------------------------------------------N 1380
               :|..|.|..|.|....|                                            .
pombe   631 PEYSRGIIYCRWLESAYAAAEKELNRLYRFYLKVDRERIGFSNKRAAILLRGANVIGMTTTGLNK 695

  Fly  1381 YVDFFD-----ICIVDEATQCTEPWTLLPMRF-GLTHMVLVGDMQQL-PAV-VLSKKAIDFGLSN 1437
            |.|..:     ||.::||....| ..::|..| .|..:||:||.:|| |.. ..:.:...|.||.
pombe   696 YRDILERINPKICFIEEAADVLE-GPIIPAVFPSLEQLVLIGDHKQLRPGCSTYALRQDPFNLSI 759

  Fly  1438 SMFDRIQRSLQTQLDKPGSYHLMHTKLFKLSTQYRMHPEICR-----------------WPN--- 1482
            |||:|:..:           .:.:|   :|:.|.||||:|.|                 ||:
pombe   760 SMFERLVEN-----------DMEYT---RLTMQRRMHPQIRRLVSSVYEDLSDYEITKYWPSIPG 810

  Fly  1483 -----QYF-----YED--------QLINAECTARFASPLIPYCVINLKYTCDSNGAQNKSISNNE 1529
                 ::|     .||        .|..|:...:||..||...|...|.||.:..|..|.:
pombe   811 MGEIRRFFLTHSRIEDNDGFASKINLFEAQMLVQFAVYLINNGVEPQKITCLTFYAAQKDL---- 871

  Fly  1530 EARFVAKLLTE---MDKHMPSKRFSYGLISPYQNQCYALSQVIPSHMNITPQTVDSYQGLEKDVI 1591
                :.:||:|   .:||.                             |...|||.|||.|.||:
pombe   872 ----IERLLSESLNREKHF-----------------------------IKVATVDGYQGEENDVV 903

  Fly  1592 IIS----NARTRGCGFLTNYQRLNVALTRPRRCLVICGNFEDL-KSVEMW----RNLLDD----- 1642
            ::|    |.||. .|||::..|:.|:|:|.||.|.|.||.:.: :|..:|    ..|::|
pombe   904 LLSLVRNNDRTE-VGFLSSPHRVCVSLSRARRGLFIFGNAQLVAESNPLWWDAINTLMNDETIQG 967

  Fly  1643 --------ARKRKVYFNLDRDDVNDLDRSLIKK 1667
                    .:...:|.| |..::.|::..|.:|
pombe   968 LGDHLPLFTKDGTIYVN-DPVELLDVNMRLTRK 999

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7504	NP_001137907.1	FHA	4..96	CDD:238017
		FHA	<10..101	CDD:224630
		AAA_11	1171..1428	CDD:289831	88/394 (22%)
		AAA_19	1194..1251	CDD:289986	25/60 (42%)
		YtxH	<1293..1347	CDD:295162	19/124 (15%)
		AAA_12	1435..1626	CDD:289832	62/235 (26%)
hrr1	NP_588411.2	DNA2	158..965	CDD:224037	215/993 (22%)
		AAA_19	387..446	CDD:289986	25/60 (42%)
		AAA_12	757..942	CDD:289832	63/236 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1112
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900