DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7504 and R03D7.2

DIOPT Version :9

Sequence 1:	NP_001137907.1	Gene:	CG7504 / 38904	FlyBaseID:	FBgn0035842	Length:	1676	Species:	Drosophila melanogaster
Sequence 2:	NP_001364577.1	Gene:	R03D7.2 / 174682	WormBaseID:	WBGene00010989	Length:	390	Species:	Caenorhabditis elegans

Alignment Length:	349	Identity:	93/349 - (26%)
Similarity:	145/349 - (41%)	Gaps:	83/349 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly  1373 SSCVKLA-------NYVDFFDICIVDEATQCT-----EPWTLLPMRFGLTHMVLVGDMQQLPAVV 1425
            ::.:|||       ...|.|||..:|||:|..     ...|:||.    :.|:|||||.|||..:
Worm    45 AAAIKLAFSQAPFLEIKDRFDITFIDEASQLALYVLGSLATMLPK----SRMILVGDMHQLPPYM 105

  Fly  1426 -------LSKKAIDFGLSNSMFDRIQRSLQTQLDKPGSYHLMHTKLFKLSTQYRMHPEICRWPNQ 1483
                   |.:.||...|:.::             |...:..||     |:..:|....|......
Worm   106 EEALPAELKRAAIGEPLTLAV-------------KGRRWPSMH-----LTRVHRCPKMITEVLGD 152

  Fly  1484 YFYEDQLINAECTARFASPL----IP--YCVINLKYTCDSNGAQNKSISNNEEARFVAKLLTEMD 1542
            .||.:.|.:::........|    :|  :.::.:.||.... |..||.||..|||:..:|:..:.
Worm   153 LFYGNTLTSSKPGVTDIPVLKAMGLPSRHPMVFVNYTSPQT-AVGKSFSNEGEARYALQLVEALT 216

  Fly  1543 KH--MPSKRFSYGLISPYQNQ-CYALSQVIPSHMNITPQTVDSYQGLEKDVIIISNART---RGC 1601
            ::  ..:|:.:..:::.|..| .|..|.   :...:|..|:|..||.|.||.|:...|:   ...
Worm   217 RYASTANKKITAAILNFYGAQYSYVYSM---AEDEVTVNTIDGCQGQEYDVTIVLLTRSDPYERS 278

  Fly  1602 GFLTNYQRLNVALTRPRRCLVI------CGNFEDLKS--------VEMWRNLLD--------DAR 1644
            .||.|..|:||||:||:...||      .||..|.:.        |..|..|::        ||
Worm   279 KFLVNANRINVALSRPKIATVIIGQRHLTGNQPDPRQPKRGRHQRVCNWARLIEKLPKECFVDA- 342

  Fly  1645 KRKVYFNLDRDDVN---DLDRSLI 1665
            |.:|....||.:|:   |..|||:
Worm   343 KDQVIAQEDRSEVSHALDPTRSLL 366

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7504	NP_001137907.1	FHA	4..96	CDD:238017
		FHA	<10..101	CDD:224630
		AAA_11	1171..1428	CDD:289831	24/73 (33%)
		AAA_19	1194..1251	CDD:289986
		YtxH	<1293..1347	CDD:295162
		AAA_12	1435..1626	CDD:289832	50/208 (24%)
R03D7.2	NP_001364577.1	DNA2	<19..302	CDD:224037	76/282 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1112
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810