DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7504 and ush1g

DIOPT Version :9

Sequence 1:	NP_001137907.1	Gene:	CG7504 / 38904	FlyBaseID:	FBgn0035842	Length:	1676	Species:	Drosophila melanogaster
Sequence 2:	XP_004918532.1	Gene:	ush1g / 100494764	XenbaseID:	XB-GENE-1013607	Length:	465	Species:	Xenopus tropicalis

Alignment Length:	305	Identity:	63/305 - (20%)
Similarity:	102/305 - (33%)	Gaps:	70/305 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   501 IETNKTSTRKRFVSTTSRDELSTTSKEIKDAPKNNVEPPKKMLRSRSKSCYIDRPVELDEHITKN 565
            |...:|....:.||...........|.|:|..|...:..::|.| |.:....||...:.  .:..
Frog   120 IAAKQTGLNPKLVSKLKERAFREAEKRIRDCAKLQRKHHERMER-RYRRDMSDRSDTMS--FSSY 181

  Fly   566 EVPLKKKYESVDNSKEELIVTLEAPAMLTTP-------TKSKTQCVKK--KATQTRGRRKTIH-S 620
            ...:.::|.|             |....|.|       ||.||:..||  |..||.|..|... .
Frog   182 SSSVSQRYPS-------------ATMFPTMPYSHAAGTTKGKTKIQKKLEKRKQTDGMFKIYEDG 233

  Fly   621 RDEIRSLTAEAEENKKISPAKQTNEEIPIPTKSPLKRNARLLNRSKSCYMDRLVISETEDPAKKV 685
            |..:|||:.....|..:...:.|       ..||.:|..:.|         |.:....||...:.
Frog   234 RKSVRSLSGLQLGNDVMFVKQGT-------YASPRERGRQHL---------RDMFLPEEDSLSRA 282

  Fly   686 IKDISPTKSD------TTDNVLNFVDVRQTRGPSVIEAPSL---------PKNRGKLRGVSAEVK 735
            |.|......|      :||:..:.:..|...|..|.....|         .:..|...|:..|||
Frog   283 ISDPGLHGGDSAHSEVSTDSGHDSLFTRPGLGTMVFRRNYLSSGLFGMGRDEGNGLQPGLGEEVK 347

  Fly   736 VKDKVLDRQRFID----------YQAEMNAKWKQKPKDKKKEDEK 770
            ::.: |.|...:|          .:.|....|::  :|.:.:|::
Frog   348 LRSR-LKRSPSLDDSIGSAGSLAVRNEQELPWEE--EDLRLDDDE 389

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID
CG7504	NP_001137907.1	FHA	4..96	CDD:238017
		FHA	<10..101	CDD:224630
		AAA_11	1171..1428	CDD:289831
		AAA_19	1194..1251	CDD:289986
		YtxH	<1293..1347	CDD:295162
		AAA_12	1435..1626	CDD:289832
ush1g	XP_004918532.1	Ank_4	5..49	CDD:372654
		ANK repeat	31..62	CDD:293786
		Ank_2	38..117	CDD:372319
		ANK repeat	64..95	CDD:293786
		SAM_USH1G	392..457	CDD:188985
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1112
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900