Protein Alignment RHOC and Mtl

DIOPT Version :10

• Sequence 1: NP_786886.1
• Gene: RHOC / 389
• HGNCID: 669
• Length: 193
• Species: Homo sapiens
• Sequence 2: NP_524533.1
• Gene: Mtl / 43319
• FlyBaseID: FBgn0039532
• Length: 195
• Species: Drosophila melanogaster
• Alignment Length: 188
• Identity: 108/188 - (57%)
• Similarity: 135/188 - (71%)
• Gaps: 1/188 - (0%)

Human     7 KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDTAGQEDYDRLRP 71
            |.|:||||..||||:||.::.|.||..||||||:||.|.::||..||.|.|||||||||||||||
  Fly     8 KCVVVGDGTVGKTCMLISYTTDCFPGEYVPTVFDNYSAPMQVDTIQVSLGLWDTAGQEDYDRLRP 72

Human    72 LSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRQDEHTRRELAKMKQ 136
            ||||.|||.|:|:|:.||.|.||:..||.||:||.||:.||||||.|.|||:|..|...||:...
  Fly    73 LSYPQTDVFLICYSVASPSSFENVTSKWYPEIKHHCPDAPIILVGTKIDLREDRETLSGLAEQGL 137

Human   137 EPVRSEEGRDMANRISAFGYLECSAKTKEGVREVFEMATRAGLQVRKNKRR-RGCPIL 193
            .|::.|:|:.:||:|.|..|:||||.|:.|::.|||.|.||.|:....||| |.|.|:
  Fly   138 TPLKREQGQKLANKIRAVKYMECSALTQRGLKPVFEEAVRAVLRPEPLKRRQRKCLIM 195

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RHOC	NP_786886.1	RhoA_like	5..179	CDD:206662	101/171 (59%)
		Effector region. /evidence=ECO:0000255	34..42		6/7 (86%)
Mtl	NP_524533.1	RHO	9..182	CDD:197554	101/172 (59%)