Protein Alignment RHOC and RhoL

DIOPT Version :10

• Sequence 1: NP_786886.1
• Gene: RHOC / 389
• HGNCID: 669
• Length: 193
• Species: Homo sapiens
• Sequence 2: NP_001247003.1
• Gene: RhoL / 41136
• FlyBaseID: FBgn0014380
• Length: 214
• Species: Drosophila melanogaster
• Alignment Length: 187
• Identity: 90/187 - (48%)
• Similarity: 125/187 - (66%)
• Gaps: 9/187 - (4%)

Human     7 KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDTAGQEDYDRLRP 71
            |:.|||||..||||:||.:::::|||.|:||||:|:..:|.||.:...|.||||||||||:||||
  Fly    37 KITIVGDGMVGKTCMLITYTRNEFPEEYIPTVFDNHACNIAVDDRDYNLTLWDTAGQEDYERLRP 101

Human    72 LSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRQDEHTRRELAKMKQ 136
            ||||.|:..|:|:||.|..|.||:..||.||::||..:||::|||.|.|||         ....:
  Fly   102 LSYPSTNCFLLCYSISSRTSFENVKSKWWPEIRHFSAHVPVVLVGTKLDLR---------IPNSE 157

Human   137 EPVRSEEGRDMANRISAFGYLECSAKTKEGVREVFEMATRAGLQVRKNKRRRGCPIL 193
            :.|.::||:.|...|.||..:|||||.|:.:::|||.|.||..:..|...::.|.||
  Fly   158 KFVTTQEGKKMRKEIHAFNLVECSAKKKQNLQQVFEEAVRAVERKPKTTSKQSCKIL 214

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RHOC	NP_786886.1	RhoA_like	5..179	CDD:206662	86/171 (50%)
		Effector region. /evidence=ECO:0000255	34..42		5/7 (71%)
RhoL	NP_001247003.1	Rho	36..198	CDD:206641	84/169 (50%)