Protein Alignment RHOC and Rac2

DIOPT Version :10

• Sequence 1: NP_786886.1
• Gene: RHOC / 389
• HGNCID: 669
• Length: 193
• Species: Homo sapiens
• Sequence 2: NP_648121.1
• Gene: Rac2 / 38831
• FlyBaseID: FBgn0014011
• Length: 192
• Species: Drosophila melanogaster
• Alignment Length: 194
• Identity: 107/194 - (55%)
• Similarity: 136/194 - (70%)
• Gaps: 3/194 - (1%)

Human     1 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDTAGQED 65
            |.||  |.|:|||||.|||||||.::.:.||..|:||||:||.|::.||.|.:.|.|||||||||
  Fly     1 MQAI--KCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDAKPINLGLWDTAGQED 63

Human    66 YDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRQDEHTRRE 130
            ||||||||||.|||.|:|||:.:|.|.||:..||.|||:|.||:|||||||.|.|||.|:.|..:
  Fly    64 YDRLRPLSYPQTDVFLICFSLVNPASFENVRAKWFPEVRHHCPSVPIILVGTKLDLRDDKQTIEK 128

Human   131 LAKMKQEPVRSEEGRDMANRISAFGYLECSAKTKEGVREVFEMATRAGL-QVRKNKRRRGCPIL 193
            |...|..|:...:|..||..|:|..||||||.|::|::.||:.|.|:.| .|.:..:|..|.:|
  Fly   129 LKDKKLTPITYPQGLAMAKEIAAVKYLECSALTQKGLKTVFDEAIRSVLCPVVRGPKRHKCALL 192

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RHOC	NP_786886.1	RhoA_like	5..179	CDD:206662	99/173 (57%)
		Effector region. /evidence=ECO:0000255	34..42		5/7 (71%)
Rac2	NP_648121.1	Rac1_like	3..176	CDD:206663	101/174 (58%)