Protein Alignment RHOC and Cdc42

DIOPT Version :10

• Sequence 1: NP_786886.1
• Gene: RHOC / 389
• HGNCID: 669
• Length: 193
• Species: Homo sapiens
• Sequence 2: NP_523414.1
• Gene: Cdc42 / 32981
• FlyBaseID: FBgn0010341
• Length: 191
• Species: Drosophila melanogaster
• Alignment Length: 187
• Identity: 96/187 - (51%)
• Similarity: 129/187 - (68%)
• Gaps: 0/187 - (0%)

Human     7 KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDTAGQEDYDRLRP 71
            |.|:|||||.|||||||.::.::||..||||||:||...:.:.|:...|.|:|||||||||||||
  Fly     5 KCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQEDYDRLRP 69

Human    72 LSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRQDEHTRRELAKMKQ 136
            ||||.|||.|:|||:.||.|.||:.|||.||:.|.|...|.:|||.:.|||.:..|..:|||.||
  Fly    70 LSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCQKTPFLLVGTQIDLRDENSTLEKLAKNKQ 134

Human   137 EPVRSEEGRDMANRISAFGYLECSAKTKEGVREVFEMATRAGLQVRKNKRRRGCPIL 193
            :|:..|:|..:|..:.|..|:||||.|::|::.||:.|..|.|:..:..::|.|..|
  Fly   135 KPITMEQGEKLAKELKAVKYVECSALTQKGLKNVFDEAILAALEPPEPTKKRKCKFL 191

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RHOC	NP_786886.1	RhoA_like	5..179	CDD:206662	92/171 (54%)
		Effector region. /evidence=ECO:0000255	34..42		6/7 (86%)
Cdc42	NP_523414.1	Cdc42	3..177	CDD:206664	92/171 (54%)