Protein Alignment Arp3 and ACTL6A

DIOPT Version :9

• Sequence 1: NP_001261559.1
• Gene: Arp3 / 38898
• FlyBaseID: FBgn0262716
• Length: 418
• Species: Drosophila melanogaster
• Sequence 2: NP_004292.1
• Gene: ACTL6A / 86
• HGNCID: 24124
• Length: 429
• Species: Homo sapiens
• Alignment Length: 462
• Identity: 123/462 - (26%)
• Similarity: 200/462 - (43%)
• Gaps: 118/462 - (25%)

  Fly     7 ACVIDVGTGYSKLGFAGNKEPQFIIPSAIAI--------------KESARVG------DTNTRRI 51
            |.|.|:|:...:.|:||...|:...|:||.:              .:..:.|      |||..|:
Human    13 ALVFDIGSYTVRAGYAGEDCPKVDFPTAIGMVVERDDGSTLMEIDGDKGKQGGPTYYIDTNALRV 77

  Fly    52 TKGIEDLDFFIGDEAFDATGYSIKYPVRHGLVEDWDLMERFLEQCVFKYLRAEPEDHYFLLTEPP 116
            .:           |..:|..     |:::|:|||||..:..|:.....::::|...|..|::|.|
Human    78 PR-----------ENMEAIS-----PLKNGMVEDWDSFQAILDHTYKMHVKSEASLHPVLMSEAP 126

  Fly   117 LNTPENREYTAEIMFETFNVPGLYIAVQAVLALAASWASRSAEERTLTGIVVDSGDGVTHVIPVA 181
            .||...||...|:|||.:|:|..::...|||...|:..|        ||:::|||...|..|||.
Human   127 WNTRAKREKLTELMFEHYNIPAFFLCKTAVLTAFANGRS--------TGLILDSGATHTTAIPVH 183

  Fly   182 EGYVIGSCIKHIPIAGRNITSFIQSLLREREVGIPPEQSLETAKAI----------KEK------ 230
            :|||:...|...|:||..||...:.|.:|..:.:.|...:.:.:|:          |||
Human   184 DGYVLQQGIVKSPLAGDFITMQCRELFQEMNIELVPPYMIASKEAVREGSPANWKRKEKLPQVTR 248

  Fly   231 --HCYICPDIAKEF---------AKYDTEPGKWIRNFSGVNTVTKAP---------FNVDVGYER 275
              |.|:|..:.::|         :.||.:            ...:.|         :|.|.|.||
Human   249 SWHNYMCNCVIQDFQASVLQVSDSTYDEQ------------VAAQMPTVHYEFPNGYNCDFGAER 301

  Fly   276 FLGPEIFFHPEFSN-----PDFTIPLSEIVDNVIQNCPIDVRRPLYNNIVLSGGSTMFKDFGRRL 335
            ...||..|.|  ||     .:..:.:|.:|...:..|.||:|..||.:::::||:|:.:.|..||
Human   302 LKIPEGLFDP--SNVKGLSGNTMLGVSHVVTTSVGMCDIDIRPGLYGSVIVAGGNTLIQSFTDRL 364

  Fly   336 QRDIKRSVDTRLR---ISENLSEGRIKPKPIDVQVITHHMQRYAVWFGGSMLASTPEFYQVCHTK 397
            .|::.:.....:|   |:.|.:..|                |::.|.|||:|||...|.|:..:|
Human   365 NRELSQKTPPSMRLKLIANNTTVER----------------RFSSWIGGSILASLGTFQQMWISK 413

  Fly   398 AAYEEYG 404
            ..|||.|
Human   414 QEYEEGG 420

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Arp3	NP_001261559.1	PTZ00280	2..417	CDD:240343	123/462 (27%)
ACTL6A	NP_004292.1	Actin	11..429	CDD:394979	123/462 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5277
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D649708at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910