Protein Alignment Arp3 and ACTL8

DIOPT Version :9

• Sequence 1: NP_001261559.1
• Gene: Arp3 / 38898
• FlyBaseID: FBgn0262716
• Length: 418
• Species: Drosophila melanogaster
• Sequence 2: NP_110439.2
• Gene: ACTL8 / 81569
• HGNCID: 24018
• Length: 366
• Species: Homo sapiens
• Alignment Length: 426
• Identity: 111/426 - (26%)
• Similarity: 195/426 - (45%)
• Gaps: 87/426 - (20%)

  Fly     1 MAGRLPACVIDVGTGYSKLGFAGNKEPQFIIPSAI---AIKES-----ARVGDTNTRRITKGIED 57
            ||.|  ..:||.|:|:.|.|.||..|||.:.|:.:   ..||:     ||      ||::.||
Human     1 MAAR--TVIIDHGSGFLKAGTAGWNEPQMVFPNIVNYLPCKENPGPSYAR------RRVSLGI-- 55

  Fly    58 LDFFIGDEAFDATGYSIKYPVRHGLVEDWDLMERFLEQCVFKYLRAEPEDHYFLLTEPPLNTPEN 122
             |....|        :..||:..|.:.:|:.:: :|...|.:..|.|.|....::||.||..|.:
Human    56 -DICHPD--------TFSYPIERGRILNWEGVQ-YLWSFVLENHRREQEVPPVIITETPLREPAD 110

  Fly   123 REYTAEIMFETFNVPGLYIAVQAVLALAASWASRSAEERTLTGIVVDSGDGVTHVIPVAEGYVIG 187
            |:...||:||..:||.:.:|.|..::|.||        ..|||:|||||.|:|.|.|..:|..:.
Human   111 RKKMLEILFELLHVPSVLLADQLQMSLYAS--------GLLTGVVVDSGYGLTRVQPFHQGRPLP 167

  Fly   188 SCIKHIPIAGRNITSFIQSLLREREVGIPPEQSLETAKAIKEKHCYICPDIAK------------ 240
            :..|.:..||:::::::...|.:.:........|||....:...||:..::.:
Human   168 ASGKTLEFAGQDLSAYLLKSLFKEDCDRRCLFQLETVAVTQMNKCYVPQNLGEALDFRERQQSAL 232

  Fly   241 -EFAKYDTEPGKWIRNFSGVNTVTKAPFNVDVGYERFLGPEIFFHPE-FSNPDFTIPLSEIVDNV 303
             |...|....|.                .|::...:.:.||:||.|: |..|..:||.: ||::|
Human   233 DESNTYQLPDGS----------------RVELTPMQRVAPEMFFSPQVFEQPGPSIPRA-IVESV 280

  Fly   304 IQNCPIDVRRPLYNNIVLSGGSTMFKDFGRRLQRDIKRSVDTRLRISENLSEGRIKPKPIDVQVI 368
             ::|.|.:|..|.::::..||:|::..|.:||.|::         :.:::|..:       ..|.
Human   281 -ESCEISLRPLLVSHVMACGGNTLYPGFTKRLFREL---------MGDHVSSTK-------ATVW 328

  Fly   369 THHMQRYAVWFGGSMLASTPEFYQVCHTKAAYEEYG 404
            ....:.::||.|.|::|....:.....::   ||||
Human   329 EGSNRNFSVWLGASVVAHLSTYQSEWMSR---EEYG 361

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Arp3	NP_001261559.1	PTZ00280	2..417	CDD:240343	110/425 (26%)
ACTL8	NP_110439.2	ACTIN	4..363	CDD:214592	109/423 (26%)
		NBD_sugar-kinase_HSP70_actin	7..362	CDD:302596	108/418 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5277
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D649708at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910