Protein Alignment Arp3 and ACTG2

DIOPT Version :10

• Sequence 1: NP_523968.1
• Gene: Arp3 / 38898
• FlyBaseID: FBgn0262716
• Length: 418
• Species: Drosophila melanogaster
• Sequence 2: NP_001606.1
• Gene: ACTG2 / 72
• HGNCID: 145
• Length: 376
• Species: Homo sapiens
• Alignment Length: 419
• Identity: 154/419 - (36%)
• Similarity: 215/419 - (51%)
• Gaps: 61/419 - (14%)

  Fly     7 ACVIDVGTGYSKLGFAGNKEPQFIIPSAIAIKESARVGDTNTRRITKGIEDLDFFIGDEAFDATG 71
            |.|.|.|:|..|.||||:..|:.:.||.        ||....:.:..|:...|.::||||....|
Human     8 ALVCDNGSGLCKAGFAGDDAPRAVFPSI--------VGRPRHQGVMVGMGQKDSYVGDEAQSKRG 64

  Fly    72 -YSIKYPVRHGLVEDWDLMERFLEQCVFKYLRAEPEDHYFLLTEPPLNTPENREYTAEIMFETFN 135
             .::|||:.||::.:||.||:......:..||..||:|..||||.|||...|||...:|||||||
Human    65 ILTLKYPIEHGIITNWDDMEKIWHHSFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFN 129

  Fly   136 VPGLYIAVQAVLALAASWASRSAEERTLTGIVVDSGDGVTHVIPVAEGYVIGSCIKHIPIAGRNI 200
            ||.:|:|:||||:|.||       .|| ||||:||||||||.:|:.|||.:...|..:.:|||::
Human   130 VPAMYVAIQAVLSLYAS-------GRT-TGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDL 186

  Fly   201 TSFIQSLLREREVGIPPEQSLETAKAIKEKHCYICPDIAKEFA----------KYDTEPGKWIRN 255
            |.::..:|.||..........|..:.||||.||:..|...|.|          .|:...|:.|
Human   187 TDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVI-- 249

  Fly   256 FSGVNTVTKAPFNVDVGYERFLGPEIFFHPEFSNPDFTIPLSEIVDNVIQNCPIDVRRPLYNNIV 320
                          .:|.|||..||..|.|.|...: :..:.|...|.|..|.||:|:.||.|.|
Human   250 --------------TIGNERFRCPETLFQPSFIGME-SAGIHETTYNSIMKCDIDIRKDLYANNV 299

  Fly   321 LSGGSTMFKDFGRRLQRDIKRSVDTRLRISENLSEGRIKPKPIDVQVITHHMQRYAVWFGGSMLA 385
            ||||:||:.....|:|::|.                .:.|..:.:::|....::|:||.|||:||
Human   300 LSGGTTMYPGIADRMQKEIT----------------ALAPSTMKIKIIAPPERKYSVWIGGSILA 348

  Fly   386 STPEFYQVCHTKAAYEEYGPSICRHNPVF 414
            |...|.|:..:|..|:|.||||. |...|
Human   349 SLSTFQQMWISKPEYDEAGPSIV-HRKCF 376

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Arp3	NP_523968.1	ASKHA_NBD_Arp3-like	7..410	CDD:466822	152/413 (37%)
ACTG2	NP_001606.1	ASKHA_NBD_actin	7..371	CDD:466823	151/411 (37%)