DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Arp3 and Actl9

DIOPT Version :9

Sequence 1:	NP_001261559.1	Gene:	Arp3 / 38898	FlyBaseID:	FBgn0262716	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	NP_899105.2	Gene:	Actl9 / 69481	MGIID:	1916731	Length:	415	Species:	Mus musculus

Alignment Length:	417	Identity:	125/417 - (29%)
Similarity:	205/417 - (49%)	Gaps:	56/417 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MAG-RLP----ACVIDVGTGYSKLGFAGNKEPQFIIPSAIAIKESARVGDTNTRRITKGIEDLDF 60
            |.| |||    |.|||:|||..|:||||..:|.:.:.:.:        |....::.||...:|:.
Mouse    39 MVGDRLPPKTGAVVIDMGTGTCKVGFAGQSQPTYTVATIL--------GCQPKKQATKDQSELET 95

  Fly    61 FIGDEAFDATGYSIKYPVRHGLVEDWDLMERFLEQCVFKYLRAEPEDHYFLLTEPPLNTPENREY 125
            |||:.|.......:..|:|:|:|.||:..|......:...|:....:|..|.::||.:...|||.
Mouse    96 FIGEAARSRPELRLVKPIRNGIVVDWEAAELIWRHILEHDLQVATHEHPLLFSDPPFSPATNREK 160

  Fly   126 TAEIMFETFNVPGLYIAVQAVLALAASWASRSAEERTLTGIVVDSGDGVTHVIPVAEGYVIGSCI 190
            ..|:.||:.:.|.||:|.|:||::.|        ...:.|:|||:|.||::.:||.:||.:...|
Mouse   161 LVEVAFESLHSPALYVASQSVLSVYA--------HGRVNGLVVDTGHGVSYTVPVVQGYNLPHAI 217

  Fly   191 KHIPIAGRNITSFIQSLLREREVGIPPEQSLETAKAIKEKHCYICPDIAKEFAKYDTEPGKWIRN 255
            :.:.:||.::|:|:..:|......: .::.|:..:.||..:||:.||..||.|:.|.|..:.::.
Mouse   218 QRLDLAGNHLTAFLAEMLLGSGFSL-QQEDLDLVENIKHHYCYLAPDFQKEQARPDEECKQSLKL 281

  Fly   256 FSGVNTVTKAPFNVDVGYERFLGPEIFFHPEFSNPDF----TIPLSEIVDNVIQNCPIDVRRPLY 316
            ..| .|||       :|.|.|..||:.|||    |:.    .|.|..:.:..:...|.::|..:.
Mouse   282 PDG-RTVT-------LGKELFQCPELLFHP----PEIPGLSPIGLPAMAEQSLLKVPQELRPHVA 334

  Fly   317 NNIVLSGGSTMFKDFGRRLQRDIKRSVDTRLRISENLSEGRIKPKPID-VQVITHHMQRYAVWFG 380
            .|::|.|||::|.....|.:.::..|:                 .|.| |.|:.|..:..:||.|
Mouse   335 RNVILCGGSSLFTGLEGRFRAELLHSL-----------------SPEDHVVVMAHPNRNLSVWIG 382

  Fly   381 GSMLASTPEFYQVCHTKAAYEEYGPSI 407
            ||:|||...|......:..|||.||.:
Mouse   383 GSILASLHAFQSCWVLREQYEERGPQV 409

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Arp3	NP_001261559.1	PTZ00280	2..417	CDD:240343	124/416 (30%)
Actl9	NP_899105.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..22
Actl9	NP_899105.2	ACTIN	48..414	CDD:214592	120/408 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5277
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D649708at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910