DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Arp3 and Actr2

DIOPT Version :9

Sequence 1:	NP_001261559.1	Gene:	Arp3 / 38898	FlyBaseID:	FBgn0262716	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	NP_001349828.1	Gene:	Actr2 / 66713	MGIID:	1913963	Length:	399	Species:	Mus musculus

Alignment Length:	422	Identity:	141/422 - (33%)
Similarity:	213/422 - (50%)	Gaps:	70/422 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 VIDVGTGYSKLGFAGNKEPQFIIPSAIA---IKESARVGDTNTRRITKGIEDLDFFIGDEAFDAT 70
            |.|.|||:.|.|:||:..|:.|.|:.:.   |:.:.:||:...:...|    :|..:||||.:..
Mouse    10 VCDNGTGFVKCGYAGSNFPEHIFPALVGRPIIRSTTKVGNIEIKNNKK----MDLMVGDEASELR 70

  Fly    71 G-YSIKYPVRHGLVEDWDLMERFLEQCVF--KYLRAEPEDHYFLLTEPPLNTPENREYTAEIMFE 132
            . ..:.||:.:|:|.:||.| :.|....|  :.|..:..:...||||||:|..:|||...|:|||
Mouse    71 SMLEVNYPMENGIVRNWDDM-KHLWDYTFGPEKLNIDTRNCKILLTEPPMNPTKNREKIVEVMFE 134

  Fly   133 TFNVPGLYIAVQAVLALAASWASRSAEERTLTGIVVDSGDGVTHVIPVAEGYVIGSCIKHIPIAG 197
            |:...|:|:|:||||.|.|        :..|||:||||||||||:.||.||:.:....:.:.|||
Mouse   135 TYQFSGVYVAIQAVLTLYA--------QGLLTGVVVDSGDGVTHICPVYEGFSLPHLTRRLDIAG 191

  Fly   198 RNITSFIQSLLREREVGIPPEQSLETAKAIKEKHCYICPDIAKE----------FAKYDTEPGKW 252
            |:||.::..||..|..........||.:.||||.||:..:|.:|          ...|....|:.
Mouse   192 RDITRYLIKLLLLRGYAFNHSADFETVRMIKEKLCYVGYNIEQEQKLALETTVLVESYTLPDGRI 256

  Fly   253 IRNFSGVNTVTKAPFNVDVGYERFLGPEIFFHPEFSNPDFTIPLSEIVDNVIQNCPIDVRRPLYN 317
            |:                ||.|||..||..|.|...|.: .:.::|::.|.||...||.|...|.
Mouse   257 IK----------------VGGERFEAPEALFQPHLINVE-GVGVAELLFNTIQAADIDTRSEFYK 304

  Fly   318 NIVLSGGSTMFKDFGRRLQRDIKRSVDTRLRIS--ENLSEGRIK----PKPIDVQVITHHMQRYA 376
            :|||||||||:.....||:|::|:....|:...  |.||:.:|:    |:           :::.
Mouse   305 HIVLSGGSTMYPGLPSRLERELKQLYLERVLKGDVEKLSKFKIRIEDPPR-----------RKHM 358

  Fly   377 VWFGGSMLA----STPEFYQVCHTKAAYEEYG 404
            |:.||::||    ....|:.   |:..|:|.|
Mouse   359 VFLGGAVLADIMKDKDNFWM---TRQEYQEKG 387

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Arp3	NP_001261559.1	PTZ00280	2..417	CDD:240343	141/422 (33%)
Actr2	NP_001349828.1	ACTIN	6..393	CDD:214592	141/422 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5277
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D649708at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820