DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Arp3 and actb1

DIOPT Version :9

Sequence 1:	NP_001261559.1	Gene:	Arp3 / 38898	FlyBaseID:	FBgn0262716	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	NP_571106.2	Gene:	actb1 / 57934	ZFINID:	ZDB-GENE-000329-1	Length:	375	Species:	Danio rerio

Alignment Length:	425	Identity:	153/425 - (36%)
Similarity:	217/425 - (51%)	Gaps:	61/425 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MAGRLPACVIDVGTGYSKLGFAGNKEPQFIIPSAIAIKESARVGDTNTRRITKGIEDLDFFIGDE 65
            |...:.|.|:|.|:|..|.||||:..|:.:.||.        ||....:.:..|:...|.::|||
Zfish     1 MDEEIAALVVDNGSGMCKAGFAGDDAPRAVFPSI--------VGRPRHQGVMVGMGQKDSYVGDE 57

  Fly    66 AFDATG-YSIKYPVRHGLVEDWDLMERFLEQCVFKYLRAEPEDHYFLLTEPPLNTPENREYTAEI 129
            |....| .::|||:.||:|.:||.||:......:..||..||:|..||||.|||...|||...:|
Zfish    58 AQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQI 122

  Fly   130 MFETFNVPGLYIAVQAVLALAASWASRSAEERTLTGIVVDSGDGVTHVIPVAEGYVIGSCIKHIP 194
            ||||||.|.:|:|:||||:|.||       .|| ||||:||||||||.:|:.|||.:...|..:.
Zfish   123 MFETFNTPAMYVAIQAVLSLYAS-------GRT-TGIVMDSGDGVTHTVPIYEGYALPHAILRLD 179

  Fly   195 IAGRNITSFIQSLLREREVGIPPEQSLETAKAIKEKHCYICPDIAKEFA----------KYDTEP 249
            :|||::|.::..:|.||..........|..:.||||.||:..|..:|..          .|:...
Zfish   180 LAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMGTAASSSSLEKSYELPD 244

  Fly   250 GKWIRNFSGVNTVTKAPFNVDVGYERFLGPEIFFHPEFSNPDFTIPLSEIVDNVIQNCPIDVRRP 314
            |:.|                .:|.|||..||..|.|.|...: :..:.|...|.|..|.:|:|:.
Zfish   245 GQVI----------------TIGNERFRCPEALFQPSFLGME-SCGIHETTFNSIMKCDVDIRKD 292

  Fly   315 LYNNIVLSGGSTMFKDFGRRLQRDIKRSVDTRLRISENLSEGRIKPKPIDVQVITHHMQRYAVWF 379
            ||.|.|||||:||:.....|:|::|.                .:.|..:.:::|....::|:||.
Zfish   293 LYANTVLSGGTTMYPGIADRMQKEIT----------------SLAPSTMKIKIIAPPERKYSVWI 341

  Fly   380 GGSMLASTPEFYQVCHTKAAYEEYGPSICRHNPVF 414
            |||:|||...|.|:..:|..|:|.||||. |...|
Zfish   342 GGSILASLSTFQQMWISKQEYDESGPSIV-HRKCF 375

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Arp3	NP_001261559.1	PTZ00280	2..417	CDD:240343	152/424 (36%)
actb1	NP_571106.2	PTZ00281	1..375	CDD:173506	152/423 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5277
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D649708at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820