DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Arp3 and si:ch211-241j12.3

DIOPT Version :9

Sequence 1:	NP_001261559.1	Gene:	Arp3 / 38898	FlyBaseID:	FBgn0262716	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	XP_017207998.2	Gene:	si:ch211-241j12.3 / 566552	ZFINID:	ZDB-GENE-040724-72	Length:	1245	Species:	Danio rerio

Alignment Length:	404	Identity:	140/404 - (34%)
Similarity:	202/404 - (50%)	Gaps:	51/404 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 VIDVGTGYSKLGFAGNKEPQFIIPSAIAIKESARVGDTNTRRITKGIEDLDFFIGDEAFDATG-Y 72
            |:|.|:|..|.|||....|..:.|:.|        |......:.....|.:.::|.:|....| .
Zfish   882 VLDSGSGLMKAGFADQDLPAAVFPTVI--------GRPKYEEVMNSCVDRELYVGHDAQHMRGVL 938

  Fly    73 SIKYPVRHGLVEDWDLMERFLEQCVFKYLRAEPEDHYFLLTEPPLNTPENREYTAEIMFETFNVP 137
            :::||:|||:|.:||.|| .|....|:.|.|.||||..||||..||..:||:...|:|||.|:||
Zfish   939 TLRYPIRHGVVSNWDEME-MLWTHAFQLLSAAPEDHPVLLTEAALNPLQNRQRMVELMFEAFSVP 1002

  Fly   138 GLYIAVQAVLALAASWASRSAEERTLTGIVVDSGDGVTHVIPVAEGYVIGSCIKHIPIAGRNITS 202
            ..::||||||||.||       .|| ||:|:||||||:|.:||.|||.:...::.:.:||.::|.
Zfish  1003 LTFVAVQAVLALYAS-------GRT-TGVVLDSGDGVSHSVPVFEGYCLPHAVQRLDLAGADVTL 1059

  Fly   203 FIQSLLREREVGIPPEQSLETAKAIKEKHCYICPDIAKEFAKYDTEPGKWIRNFSGVNTVTKAPF 267
            .:|.||.|..|.:.....||..:.:||:.|::..|...|....::|          :........
Zfish  1060 QLQKLLLESGVCLRTSAELEIVREMKERCCFVSVDYEAEMKSSESE----------IQYTLPDGH 1114

  Fly   268 NVDVGYERFLGPEIFFHPEFSNPDFTIPLSEIVDNVIQNCPIDVRRPLYNNIVLSGGSTMFKDFG 332
            .|.:..:||..|||.|.||....|. ..|.|.|...|....:|:||....||:||||:|:.....
Zfish  1115 TVPLASQRFRAPEILFRPELIGRDH-YGLHESVFRSILQSDLDLRRSFVGNILLSGGNTLLSGLA 1178

  Fly   333 RRLQRDIKRSVDTRLRISENLSEGRIKPKPID----VQVITHHMQRYAVWFGGSMLASTPEFYQV 393
            .|||.:::..|                  |:|    |:|.:...:.::||.||:.|||.||....
Zfish  1179 ERLQLEVRAMV------------------PLDLSACVRVSSPPDRDFSVWSGGAALASLPEQQSA 1225

  Fly   394 CHTKAAYEEYGPSI 407
            ..:.|.|||:||.|
Zfish  1226 WISAAEYEEFGPQI 1239

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Arp3	NP_001261559.1	PTZ00280	2..417	CDD:240343	140/404 (35%)
si:ch211-241j12.3	XP_017207998.2	Neuromodulin_N	<411..625	CDD:331332
si:ch211-241j12.3	XP_017207998.2	ACTIN	878..1245	CDD:214592	140/404 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D649708at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010