Protein Alignment Arp3 and ACTR10

DIOPT Version :9

• Sequence 1: NP_001261559.1
• Gene: Arp3 / 38898
• FlyBaseID: FBgn0262716
• Length: 418
• Species: Drosophila melanogaster
• Sequence 2: XP_011535262.1
• Gene: ACTR10 / 55860
• HGNCID: 17372
• Length: 424
• Species: Homo sapiens
• Alignment Length: 455
• Identity: 111/455 - (24%)
• Similarity: 189/455 - (41%)
• Gaps: 110/455 - (24%)

  Fly     3 GRLPACVIDVGTGYSKLGFAGNKEPQFIIPSAIAIKESARVGDTNTRRITKGIEDLDFFIGDEAF 67
            |...|.|||:|..::|.||||...|:.||||.|     .|.|      :.|.:..:.:.|..|
Human    11 GEKTAVVIDLGEAFTKCGFAGETGPRCIIPSVI-----KRAG------MPKPVRVVQYNINTE-- 62

  Fly    68 DATGYSIKYPVRHGLVEDWDLMERFLEQCVFKYLRAEPEDHYFLLTEPPLNTPENREYTAEIMFE 132
                            |.:..::.|:....|::|...|.|...::.|..|.....||....::|:
Human    63 ----------------ELYSYLKEFIHILYFRHLLVNPRDRRVVIIESVLCPSHFRETLTRVLFK 111

  Fly   133 TFNVPGLYIAVQAVLALAASWASRSAEERTL---TGIVVDSGDGVTHVIPVAEGYVIGSCIKHIP 194
            .|.||.:.:|...::||.           ||   :.:|:|.|...:.|:|:.||..:.:|...:|
Human   112 YFEVPSVLLAPSHLMALL-----------TLGINSAMVLDCGYRESLVLPIYEGIPVLNCWGALP 165

  Fly   195 IAGRNITSFIQSLLRE---------REVGIP------PEQSLETAKA----IKEKHCYICPDIAK 240
            :.|:.:...:::.|.|         :|..:|      ||..||..|.    :|.:.|:: .|:.:
Human   166 LGGKALHKELETQLLEQCTVDTSVAKEQSLPSVMGSVPEGVLEDIKGLLFFLKARTCFV-SDLKR 229

  Fly   241 ----EFAKYDTEPGKWIRNFSGVNTVTKAPFNVDVGYE-----RFLGP------EIFFHPEFSNP 290
                :.||:         |..|.|.....|.|||...:     ..||.      ||.|  |..|.
Human   230 GLKIQAAKF---------NIDGNNERPSPPPNVDYPLDGEKILHILGSIRDSVVEILF--EQDNE 283

  Fly   291 DFTIPLSEIVDNVIQNCPIDVRRPLYNNIVLSGGSTMFKDFGRRLQRDIKRSVD-TRLRISENLS 354
            :.:: .:.|:|::|| ||||.|:.|..|:|:.||::|...|..||..:|:..|: .:.:.:....
Human   284 EQSV-ATLILDSLIQ-CPIDTRKQLAENLVVIGGTSMLPGFLHRLLAEIRYLVEKPKYKKALGTK 346

  Fly   355 EGRIKPKPIDVQVITHHMQRYAVWFGGSMLASTPEFYQVCHTKAAYEEYG------PSICR-HNP 412
            ..||...|.....:        .|.||::..:..:   :..:::..:||.      |..|. :||
Human   347 TFRIHTPPAKANCV--------AWLGGAIFGALQD---ILGSRSVSKEYYNQTGRIPDWCSLNNP 400

  Fly   413  412
            Human   401  400

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Arp3	NP_001261559.1	PTZ00280	2..417	CDD:240343	111/455 (24%)
ACTR10	XP_011535262.1	NBD_sugar-kinase_HSP70_actin	12..389	CDD:302596	106/441 (24%)
		Actin	14..395	CDD:278451	107/445 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5277
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810