Protein Alignment Arp3 and ACTL6B

DIOPT Version :9

• Sequence 1: NP_001261559.1
• Gene: Arp3 / 38898
• FlyBaseID: FBgn0262716
• Length: 418
• Species: Drosophila melanogaster
• Sequence 2: NP_057272.1
• Gene: ACTL6B / 51412
• HGNCID: 160
• Length: 426
• Species: Homo sapiens
• Alignment Length: 447
• Identity: 116/447 - (25%)
• Similarity: 195/447 - (43%)
• Gaps: 91/447 - (20%)

  Fly     7 ACVIDVGTGYSKLGFAGNKEPQFIIPSAIAIKESARVG-----------------DTNTRRITKG 54
            |.|.|:|:...:.|:||...|:...|:.:.:..:...|                 |||...:.:
Human    13 ALVFDIGSFSVRAGYAGEDCPKADFPTTVGLLAAEEGGGLELEGDKEKKGKIFHIDTNALHVPR- 76

  Fly    55 IEDLDFFIGDEAFDATGYSIKYPVRHGLVEDWDLMERFLEQCVFKYLRAEPEDHYFLLTEPPLNT 119
                           .|..:..|:::|::|||:.....|:....|::::||..|..|::|.|.||
Human    77 ---------------DGAEVMSPLKNGMIEDWECFRAILDHTYSKHVKSEPNLHPVLMSEAPWNT 126

  Fly   120 PENREYTAEIMFETFNVPGLYIAVQAVLALAASWASRSAEERTLTGIVVDSGDGVTHVIPVAEGY 184
            ...||...|:|||.:|:|..::...|||...|:..|        ||:|:|||...|..|||.:||
Human   127 RAKREKLTELMFEQYNIPAFFLCKTAVLTAFANGRS--------TGLVLDSGATHTTAIPVHDGY 183

  Fly   185 VIGSCIKHIPIAGRNITSFIQSLLREREVGIPPEQSLETAKAI----------KEK--------H 231
            |:...|...|:||..|:...:.|.:|..:.|.|...:...:.:          |||        |
Human   184 VLQQGIVKSPLAGDFISMQCRELFQEMAIDIIPPYMIAAKEPVREGAPPNWKKKEKLPQVSKSWH 248

  Fly   232 CYICPDIAKEF---------AKYDTEPGKWIRNFSGVNTVTKAPFNVDVGYERFLGPEIFFHPEF 287
            .|:|.::.::|         :.||.:..   .....|:......:|.|.|.||...||..|.|
Human   249 NYMCNEVIQDFQASVLQVSDSPYDEQVA---AQMPTVHYEMPNGYNTDYGAERLRIPEGLFDP-- 308

  Fly   288 SN-----PDFTIPLSEIVDNVIQNCPIDVRRPLYNNIVLSGGSTMFKDFGRRLQRDIKRSVDTRL 347
            ||     .:..:.:..:|...|..|.||:|..||.:::::||:|:.:.|..||.|::.:.....:
Human   309 SNVKGLSGNTMLGVGHVVTTSIGMCDIDIRPGLYGSVIVTGGNTLLQGFTDRLNRELSQKTPPSM 373

  Fly   348 RISENLSEGRIKPKPIDVQVITHHMQRYAVWFGGSMLASTPEFYQVCHTKAAYEEYG 404
            |:....|...::             ::::.|.|||:|||...|.|:..:|..|||.|
Human   374 RLKLIASNSTME-------------RKFSPWIGGSILASLGTFQQMWISKQEYEEGG 417

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Arp3	NP_001261559.1	PTZ00280	2..417	CDD:240343	116/447 (26%)
ACTL6B	NP_057272.1	Actin	11..426	CDD:394979	116/447 (26%)
		Essential for mediating its function in dendritic development, may contribute to neuronal-specific targeting. /evidence=ECO:0000250|UniProtKB:Q99MR0	39..82		5/58 (9%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5277
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D649708at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910