DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Arp3 and actr2a

DIOPT Version :9

Sequence 1:	NP_001261559.1	Gene:	Arp3 / 38898	FlyBaseID:	FBgn0262716	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	XP_021326108.1	Gene:	actr2a / 406820	ZFINID:	ZDB-GENE-040426-2894	Length:	399	Species:	Danio rerio

Alignment Length:	420	Identity:	139/420 - (33%)
Similarity:	212/420 - (50%)	Gaps:	60/420 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 VIDVGTGYSKLGFAGNKEPQFIIPSAIA---IKESARVGDTNTRRITKGIEDLDFFIGDEAFDAT 70
            |.|.|||:.|.|:||:..|:.|.|:.:.   |:.:|:||:..    .|....:|..:||||.:..
Zfish    10 VCDNGTGFVKCGYAGSNFPEHIFPALVGRPIIRSTAKVGNIE----IKDYRRMDLMVGDEASELR 70

  Fly    71 G-YSIKYPVRHGLVEDWDLMERFLEQCVF--KYLRAEPEDHYFLLTEPPLNTPENREYTAEIMFE 132
            . ..:.||:.:|:|.:||.| :.|....|  :.|..:..:...||||||:|..:|||...|:|||
Zfish    71 SMLEVNYPMENGIVRNWDDM-KHLWDYTFGPEKLNIDSRNCKILLTEPPMNPTKNREKIIEVMFE 134

  Fly   133 TFNVPGLYIAVQAVLALAASWASRSAEERTLTGIVVDSGDGVTHVIPVAEGYVIGSCIKHIPIAG 197
            |:...|:|||:||||.|.|        :..|||:||||||||||:.||.||:.:....:.:.|||
Zfish   135 TYQFSGVYIAIQAVLTLYA--------QGLLTGVVVDSGDGVTHICPVYEGFSLPHLTRRLDIAG 191

  Fly   198 RNITSFIQSLLREREVGIPPEQSLETAKAIKEKHCYICPDIAKE----------FAKYDTEPGKW 252
            |:||.::..||..|..........||.:.:|||.||:..:|.:|          ...|....|:.
Zfish   192 RDITRYLIKLLLLRGYAFNHSADFETVRMMKEKLCYVGYNIEQEQKLALETTVLVESYTLPDGRV 256

  Fly   253 IRNFSGVNTVTKAPFNVDVGYERFLGPEIFFHPEFSNPDFTIPLSEIVDNVIQNCPIDVRRPLYN 317
            |:                ||.|||..||..|.|...|.: .:.::|::.|.||...||.|...|.
Zfish   257 IK----------------VGGERFEAPEALFQPHLINVE-GVGVAELLFNTIQAADIDTRAEFYK 304

  Fly   318 NIVLSGGSTMFKDFGRRLQRDIKRSVDTRLRISENLSEGRI-KPKPIDVQVITHHMQRYAVWFGG 381
            :|||||||||:.....||:|::|:      ...|.:.:|.: |.....:::.....:::.|:.||
Zfish   305 HIVLSGGSTMYPGLPSRLERELKQ------LYLERVLKGDVDKLSKFKIRIEDPPRRKHMVFLGG 363

  Fly   382 SMLA----STPEFYQVCHTKAAYEEYGPSI 407
            ::||    ....|:.   |:..|:|.|..:
Zfish   364 AVLADIMKDKDNFWM---TREEYQEKGTRV 390

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Arp3	NP_001261559.1	PTZ00280	2..417	CDD:240343	139/420 (33%)
actr2a	XP_021326108.1	ACTIN	6..393	CDD:214592	139/420 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5277
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D649708at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820