Protein Alignment Arp3 and ACTBL2

DIOPT Version :9

• Sequence 1: NP_001261559.1
• Gene: Arp3 / 38898
• FlyBaseID: FBgn0262716
• Length: 418
• Species: Drosophila melanogaster
• Sequence 2: NP_001017992.1
• Gene: ACTBL2 / 345651
• HGNCID: 17780
• Length: 376
• Species: Homo sapiens
• Alignment Length: 421
• Identity: 149/421 - (35%)
• Similarity: 215/421 - (51%)
• Gaps: 61/421 - (14%)

  Fly     5 LPACVIDVGTGYSKLGFAGNKEPQFIIPSAIAIKESARVGDTNTRRITKGIEDLDFFIGDEAFDA 69
            |.|.|:|.|:|..|.||.|:..|:.:.||.|        |....:.:..|:...|.::||||...
Human     6 LSALVVDNGSGMCKAGFGGDDAPRAVFPSMI--------GRPRHQGVMVGMGQKDCYVGDEAQSK 62

  Fly    70 TG-YSIKYPVRHGLVEDWDLMERFLEQCVFKYLRAEPEDHYFLLTEPPLNTPENREYTAEIMFET 133
            .| .::|||:.||:|.:||.||:......:..||..|::|..||||.|||...|||...:||||.
Human    63 RGVLTLKYPIEHGVVTNWDDMEKIWYHTFYNELRVAPDEHPILLTEAPLNPKINREKMTQIMFEA 127

  Fly   134 FNVPGLYIAVQAVLALAASWASRSAEERTLTGIVVDSGDGVTHVIPVAEGYVIGSCIKHIPIAGR 198
            ||.|.:|:|:||||:|.||       .|| ||||:||||||||::|:.|||.:...|..:.:|||
Human   128 FNTPAMYVAIQAVLSLYAS-------GRT-TGIVMDSGDGVTHIVPIYEGYALPHAILRLDLAGR 184

  Fly   199 NITSFIQSLLREREVGIPPEQSLETAKAIKEKHCYICPDIAKEFAK----------YDTEPGKWI 253
            ::|.::..:|.||..........|..:.:|||.||:..|..:|..:          |:...|:.|
Human   185 DLTDYLMKILTERGYNFTTTAEREIVRDVKEKLCYVALDFEQEMVRAAASSSPERSYELPDGQVI 249

  Fly   254 RNFSGVNTVTKAPFNVDVGYERFLGPEIFFHPEFSNPDFTIPLSEIVDNVIQNCPIDVRRPLYNN 318
                            .:|.|||..||..|.|.|...: :..:.|...|.|..|.:|:|:.||.|
Human   250 ----------------TIGNERFRCPEAIFQPSFLGIE-SSGIHETTFNSIMKCDVDIRKDLYAN 297

  Fly   319 IVLSGGSTMFKDFGRRLQRDIKRSVDTRLRISENLSEGRIKPKPIDVQVITHHMQRYAVWFGGSM 383
            .||||||||:.....|:|::|.                .:.|..:.:::|....::|:||.|||:
Human   298 TVLSGGSTMYPGIADRMQKEII----------------TLAPSTMKIKIIAPPERKYSVWIGGSI 346

  Fly   384 LASTPEFYQVCHTKAAYEEYGPSICRHNPVF 414
            |||...|.|:..:|..|:|.||.|. |...|
Human   347 LASLSTFQQMWISKQEYDEAGPPIV-HRKCF 376

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Arp3	NP_001261559.1	PTZ00280	2..417	CDD:240343	149/421 (35%)
ACTBL2	NP_001017992.1	NBD_sugar-kinase_HSP70_actin	1..376	CDD:327376	148/419 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5277
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D649708at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820